Intra-arterial transplantation of stem cells in large animals as a minimally-invasive strategy for the treatment of disseminated neurodegeneration

Autor: Izabela Malysz-Cymborska, Dominika Golubczyk, Lukasz Kalkowski, Joanna Kwiatkowska, Michal Zawadzki, Joanna Głodek, Piotr Holak, Joanna Sanford, Kamila Milewska, Zbigniew Adamiak, Piotr Walczak, Miroslaw Janowski

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract Stem cell transplantation proved promising in animal models of neurological diseases; however, in conditions with disseminated pathology such as ALS, delivery of cells and their broad distribution is challenging. To address this problem, we

Externí odkaz: https://doaj.org/article/7418b613efca429b83753bd9a48ff63c

MRI-guided intracerebral convection-enhanced injection of gliotoxins to induce focal demyelination in swine.

Autor: Lukasz Kalkowski, Izabela Malysz-Cymborska, Dominika Golubczyk, Miroslaw Janowski, Piotr Holak, Kamila Milewska, Dorota Kedziorek, Zbigniew Adamiak, Wojciech Maksymowicz, Piotr Walczak

Publikováno v: PLoS ONE, Vol 13, Iss 10, p e0204650 (2018)

Demyelinating disorders such as multiple sclerosis (MS) or transverse myelitis are devastating neurological conditions with no effective cure. Prevention of myelin loss or restoration of myelin are key for successful therapy. To investigate the disea

Externí odkaz: https://doaj.org/article/fc21baa21fc245429efa0b0d5bbe75f4

Two in one: use of divalent manganese ions as both cross-linking and MRI contrast agent for intrathecal injection of hydrogel-embedded stem cells

Autor: Piotr Walczak, Kamila Milewska, Miroslaw Janowski, Lukasz Kalkowski, Joanna Kwiatkowska, Piotr Holak, Dominika Golubczyk, Izabela Malysz-Cymborska, Joaquim M. Oliveira

Publikováno v: Pharmaceutics
Volume 13
Issue 7
Pharmaceutics, Vol 13, Iss 1076, p 1076 (2021)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Cell therapy is a promising tool for treating central nervous system (CNS) disorders; though, the translational efforts are plagued by ineffective delivery methods. Due to the large contact surface with CNS and relatively easy access, the intrathecal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e91008b6628f015094163fd107ec602
https://hdl.handle.net/1822/74317

Intra-Arterial Transplantation of Stem Cells in Large Animals – A Minimally-Invasive Strategy for the Treatment of Disseminated Neurodegeneration

Autor: Izabela Malysz-Cymborska, Dominika Golubczyk, Lukasz Kalkowski, Joanna Kwiatkowska, Michal Zawadzki, Joanna Glodek, Piotr Holak, Joanna Sanford, Kamila Milewska, Zbigniew Adamiak, Piotr Walczak, Miroslaw Janowski

Stem cell transplantation proved promising in animal models of neurological diseases; however, in conditions with disseminated pathology such as ALS, delivery of cells and their broad distribution is challenging. To address this problem, we explored

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::912dba79a35e2d3f82dbdd52eb75f575
https://doi.org/10.21203/rs.3.rs-114224/v1

Feline hip joint anatomy in magnetic resonance images

Autor: Angelika Tobolska, Joanna Głodek, Isaac Bada, Kamila Milewska, Łukasz Grabarczyk, Wojciech Maksymowicz, Zbigniew Adamiak

Publikováno v: Anatomia, histologia, embryologiaREFERENCES. 48(5)

The aim of this study was to develop an anatomical model of the feline hip joint for low-field magnetic resonance imaging (LF-MRI) based on high-field magnetic resonance imaging (HF-MRI). The study was performed on six adult clinically healthy Europe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8be0ada51869cb97efdc7716bf6ba5
https://pubmed.ncbi.nlm.nih.gov/31348547