Výsledky vyhledávání - "Kamila C. Silva"

Akademický článek

Inactivation of AMPK Mediates High Phosphate-Induced Extracellular Matrix Accumulation via NOX4/TGFß-1 Signaling in Human Mesangial Cells

Autor: Alexandros Papadimitriou, Elisa B.M.I. Peixoto, Kamila C. Silva, Jacqueline M. Lopes de Faria, José B. Lopes de Faria

Publikováno v: Cellular Physiology and Biochemistry, Vol 34, Iss 4, Pp 1260-1272 (2014)

Background/Aims: High phosphate (Pi) levels and extracellular matrix (ECM) accumulation are associated with chronic kidney disease progression. However, how high Pi levels contribute to ECM accumulation in mesangial cells is unknown. The present stud

Externí odkaz: https://doaj.org/article/88db5d9c35aa41fea0dcc580b0300f3d

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Influência dos excipientes nas propriedades de fluxo e dissolução de cápsulas manipuladas de aciclovir

Autor: Kamila C. Silva, Karina L. Romano, Whocely V. Castro, Ana Julia Pereira Santinho Gomes

Publikováno v: Brazilian Journal of Health and Pharmacy. 3:34-50

Acyclovir (ACV) is used to treat infectious diseases caused by the herpes virus. Its high cohesiveness makes encapsulation difficult and compromises the final quality of the compounded product. The aim of this work was to select excipients capable of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a527bb9bbef85eba35681f8e2e75b1ca
https://doi.org/10.29327/226760.3.1-4

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Theobromine increases NAD+/Sirt-1 activity and protects the kidney under diabetic conditions

Autor: Elisa B.M.I. Peixoto, José B. Lopes de Faria, Cynthia M. Borges, Kamila C. Silva, Jacqueline M. Lopes de Faria, Alexandros Papadimitriou

Publikováno v: American Journal of Physiology-Renal Physiology. 308:F209-F225

Reduction in sirtuin 1 (Sirt-1) is associated with extracellular matrix (ECM) accumulation in the diabetic kidney. Theobromine may reduce kidney ECM accumulation in diabetic rats. In the current study, we aimed to unravel, under diabetic conditions,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ec4b587ebdcb29e54f1d8d213d11c3
https://doi.org/10.1152/ajprenal.00252.2014

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Inactivation of AMPK Mediates High Phosphate-Induced Extracellular Matrix Accumulation via NOX4/TGFß-1 Signaling in Human Mesangial Cells

Autor: Kamila C. Silva, Jacqueline M. Lopes de Faria, José B. Lopes de Faria, Elisa B.M.I. Peixoto, Alexandros Papadimitriou

Publikováno v: Cellular Physiology and Biochemistry, Vol 34, Iss 4, Pp 1260-1272 (2014)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c34d06bfdb86b34e1b725f9da99f48
http://www.karger.com/Article/FullText/366336

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Uncoupling Endothelial Nitric Oxide Synthase Is Ameliorated by Green Tea in Experimental Diabetes by Re-establishing Tetrahydrobiopterin Levels

Autor: Jacqueline M. Lopes de Faria, José B. Lopes de Faria, Alexandros Papadimitriou, Kamila C. Silva, Aline M. Faria

Publikováno v: Diabetes

The current study investigated the potential of green tea (GT) to improve uncoupling of endothelial nitric oxide synthase (eNOS) in diabetic conditions. In rats with streptozotocin-induced diabetes, nitric oxide (NO) bioavailability was reduced by un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f938319512207888885f798469c4b30a
https://doi.org/10.2337/db11-1241

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Diabetic Retinal Neurodegeneration Is Associated With Mitochondrial Oxidative Stress and Is Improved by an Angiotensin Receptor Blocker in a Model Combining Hypertension and Diabetes

Autor: Jacqueline M. Lopes de Faria, Subrata K. Biswas, Kamila C. Silva, Mariana Aparecida Brunini Rosales, José B. Lopes de Faria

Publikováno v: Diabetes

OBJECTIVE Diabetic retinopathy displays the features of a neurodegenerative disease. Oxidative stress is involved in the pathogenesis of diabetic retinopathy. This investigation sought to determine whether hypertension exacerbates the oxidative stres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9254c300a7c1e9de7bd03a4059acb248
https://doi.org/10.2337/db09-0166

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Polyphenol-enriched cocoa protects the diabetic retina from glial reaction through the sirtuin pathway

Autor: José B. Lopes de Faria, Mariana Ap.B. Rosales, Kamila C. Silva, Jacqueline M. Lopes de Faria, Alexandros Papadimitriou, Diego Andreazzi Duarte, Jacqueline Nakau Mendonça, Norberto Peporine Lopes, Vitor Hugo O. Amancio

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
ResearcherID

Cocoa is rich in flavonoids, which are potent antioxidants with established benefits for cardiovascular health but unproven effects on neurodegeneration. Sirtuins (SIRTs), which make up a family of deacetylases, are thought to be sensitive to oxidati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42ae40de289c5e0a6936a73a8cea5d7

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Endocytosis of tight junctions caveolin nitrosylation dependent is improved by cocoa via opioid receptor on RPE cells in diabetic conditions

Autor: Mariana Aparecida Brunini Rosales, Diego Andreazzi Duarte, Franco Aparecido Rossato, José B. Lopes de Faria, Jacqueline M. Lopes de Faria, Kamila C. Silva

Publikováno v: Investigative ophthalmologyvisual science. 55(9)

PURPOSE Retinal pigment epithelium cells, along with tight junction (TJ) proteins, constitute the outer blood retinal barrier (BRB). Contradictory findings suggest a role for the outer BRB in the pathogenesis of diabetic retinopathy (DR). The aim of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd9f053d1c8750e52998f9cbdd4a654
https://pubmed.ncbi.nlm.nih.gov/25190662

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Reduced LRP6 expression and increase in the interaction of GSK3β with p53 contribute to podocyte apoptosis in diabetes mellitus and are prevented by green tea

Autor: Chiara Montemurro, P.P. Joazeiro, Kamila C. Silva, Daniel Teixeira, E. B. M. I. Peixoto, Diego Andreazzi Duarte, J. Lopes de Faria, Alexandros Papadimitriou, J. B. Lopes de Faria

Publikováno v: The Journal of nutritional biochemistry. 26(4)

In diabetes mellitus (DM), podocyte apoptosis leads to albuminuria and nephropathy progression. Low-density lipoprotein receptor-related protein 6 (LRP6) is WNT pathway receptor that is involved in podocyte death, adhesion and motility. Glycogen synt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f593460abe7efeefe2778acbea988a7
https://pubmed.ncbi.nlm.nih.gov/25655048

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Spatial distribution of theobromine--a low MW drug--in tissues via matrix-free NALDI-MS imaging

Autor: Alessandra, Tata, Chiara, Montemurro, Andreia M, Porcari, Kamila C, Silva, José B, Lopes de Faria, Marcos N, Eberlin

Publikováno v: Drug testing and analysis. 6(9)

The ability of nano-assisted laser desorption-ionization mass spectrometry imaging (NALDI-IMS) to provide selective chemical monitoring with appropriate spatial distribution of a low molecular drug in a biological tissue was investigated. NALDI-IMS i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4cbb534a30f1f3bbe9972d4b4e98e797
https://pubmed.ncbi.nlm.nih.gov/25066957

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