Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kamila, Stranska"'
Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes
Autor:
Helena Olbertova, Karla Plevova, Sarka Pavlova, Jitka Malcikova, Jana Kotaskova, Kamila Stranska, Michaela Spunarova, Martin Trbusek, Veronika Navrkalova, Barbara Dvorackova, Nikola Tom, Karol Pal, Marie Jarosova, Yvona Brychtova, Anna Panovska, Michael Doubek, Sarka Pospisilova
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Telomeres are protective structures at chromosome ends which shorten gradually with increasing age. In chronic lymphocytic leukemia (CLL), short telomeres have been associated with unfavorable disease outcome, but the link between
Externí odkaz:
https://doaj.org/article/62c7fe3bce37456bb78f5e4434870ef7
Autor:
Kamila Stranska, Karla Plevova, Hana Skuhrova Francova, Hana Skabrahova, Magdalena von Jagwitz-Biegnitz, Lenka Radova, Anna Panovska, Stanislava Hrobkova, Yvona Brychtova, Renata Urbanova, Lukas Smolej, Martin Simkovic, Jana Zuchnicka, Lekaa Mohammadova, Martin Spacek, Jiri Mayer, Sarka Pospisilova, Michael Doubek
Publikováno v:
Biomedical Papers, Vol 164, Iss 4, Pp 425-434 (2020)
Aims: This is a nation-wide survey of chronic lymphocytic leukemia (CLL) patients at six large hematology centers in the Czech Republic. The aim was to identify specific populations, social, and health characteristics of CLL subgroups divided accordi
Externí odkaz:
https://doaj.org/article/98abe80f90664881b5133fa1d14a42e8
Publikováno v:
Biomedical Papers, Vol 163, Iss 1, Pp 1-7 (2019)
Telomeres are repetitive DNA sequences protecting physical ends of linear chromosomes against degradation and end-to-end chromosomal fusion. Telomeres shorten with each cell division, which regulates the cellular lifespan in somatic cells and limits
Externí odkaz:
https://doaj.org/article/9fbc4b49a50b4c7f99290c7f5ef371fb
Autor:
Veronika, Navrkalova, Karla, Plevova, Jakub, Hynst, Karol, Pal, Andrea, Mareckova, Tomas, Reigl, Hana, Jelinkova, Zuzana, Vrzalova, Kamila, Stranska, Sarka, Pavlova, Anna, Panovska, Andrea, Janikova, Michael, Doubek, Jana, Kotaskova, Sarka, Pospisilova
Publikováno v:
The Journal of molecular diagnostics : JMD. 23(8)
B-cell neoplasms represent a clinically heterogeneous group of hematologic malignancies with considerably diverse genomic architecture recently endorsed by next-generation sequencing (NGS) studies. Because multiple genetic defects have a potential or