Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kamil Pérez-Capote"'
Autor:
Sergio González, David Moreno-Delgado, Estefanía Moreno, Kamil Pérez-Capote, Rafael Franco, Josefa Mallol, Antoni Cortés, Vicent Casadó, Carme Lluís, Jordi Ortiz, Sergi Ferré, Enric Canela, Peter J McCormick
Publikováno v:
PLoS Biology, Vol 10, Iss 6, p e1001347 (2012)
The role of the pineal gland is to translate the rhythmic cycles of night and day encoded by the retina into hormonal signals that are transmitted to the rest of the neuronal system in the form of serotonin and melatonin synthesis and release. Here w
Externí odkaz:
https://doaj.org/article/8bed974b365c4c47beb867828b5fe724
Autor:
Gemma Navarro, Carmen Lluis, Joaquim A. Ribeiro, Sandra H. Vaz, Fiorenzo Conti, Ana M. Sebastião, Sofia Cristóvão-Ferreira, Marc Brugarolas, Kamil Pérez-Capote, Rafael Franco, Vicent Casadó, Giorgia Fattorini, Peter J. McCormick
Publikováno v:
The Journal of Neuroscience. 31:15629-15639
Astrocytes play a key role in modulating synaptic transmission by controlling the available extracellular GABA via the GAT-1 and GAT-3 GABA transporters (GATs). Using primary cultures of rat astrocytes, we show here that an additional level of regula
Autor:
Antoni Cortés, Josefa Mallol, Enric I. Canela, Rafael Franco, Carmen Lluis, Kamil Pérez-Capote, Sergi Ferré, Vicent Casadó
Publikováno v:
Pharmacol Ther
G protein-coupled receptors (GPCR) are targeted by many therapeutic drugs marketed to fight against a variety of diseases. Selection of novel lead compounds are based on pharmacological parameters obtained assuming that GPCR are monomers. However, ma
Autor:
Rafael Franco, Enric I. Canela, Carme Lluís, Kamil Pérez-Capote, Antonio Cortés, Josefa Mallol, Vicent Casadó, Sergi Ferré
Publikováno v:
Brain Research Reviews. 58:475-482
Studies performed in the last 10 years have provided solid evidence indicating that G-protein-coupled receptors are expressed on the plasma membrane as homo and heterodimers. The first consequence of this fact is that homo and heterodimers are the tr
Publikováno v:
Glia. 45:258-268
We studied the influence of glial cells on the neuronal response to glutamate toxicity in cerebellar granule cell cultures. We compared the effect of glutamate on neuronal viability in neuronal vs. neuronal-glial cultures and determined this effect a
Autor:
Sergio González, David Moreno-Delgado, Estefanía Moreno, Kamil Pérez-Capote, Rafael Franco, Josefa Mallol, Antoni Cortés, Vicent Casadó, Carme Lluís, Jordi Ortiz, Sergi Ferré, Enric Canela, Peter J McCormick
Publikováno v:
PLoS Biology
PLoS Biology, Vol 10, Iss 6, p e1001347 (2012)
PLoS Biology, Vol 10, Iss 6, p e1001347 (2012)
The role of the pineal gland is to translate the rhythmic cycles of night and day encoded by the retina into hormonal signals that are transmitted to the rest of the neuronal system in the form of serotonin and melatonin synthesis and release. Here w
Autor:
Antoni Cortés, Enric I. Canela, Carme Lluís, Vicent Casadó, Rafael Franco, Kamil Pérez-Capote, Josefa Mallol, Jana Barkešová, Estefanía Moreno, Eduard Gracia
Publikováno v:
The Biochemical journal. 435(3)
A2ARs (adenosine A2A receptors) are highly enriched in the striatum, which is the main motor control CNS (central nervous system) area. BRET (bioluminescence resonance energy transfer) assays showed that A2AR homomers may act as cell-surface ADA (ade
Autor:
Anabel Molero, Antoni Cortés, Miriam Royo, Sergio González, Fernando Albericio, Vicent Casadó, Kamil Pérez-Capote, Peter J. McCormick, Rafael Franco, Marc Vendrell, Carme Lluís
Publikováno v:
Journal of medicinal chemistry. 54(4)
The incorporation of chemical modifications into the structure of bioactive compounds is often difficult because the biological properties of the new molecules must be retained with respect to the native ligand. Ergopeptides, with their high affiniti
Publikováno v:
Neuroscience letters. 410(1)
We studied the involvement of two members of the CCAAT/enhancer binding proteins (C/EBPs) family of transcription factors, C/EBPalpha and C/EBPbeta, in glial activation induced by different stimuli in rat cerebellar neuronal-glial cultures. Glial act
Publikováno v:
Journal of neurochemistry. 94(1)
We have studied glial activation in rat cerebellar neuronal-glial cultures after inducing neuronal death using various stimuli. Cultures were exposed to 100 microm glutamate for 20 min, which induces excitotoxic neuronal death, or to potassium/serum