Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kamil, Mika"'
Autor:
Visarut Buranasudja, Kittipong Sanookpan, Sornkanok Vimolmangkang, Asma Binalee, Kamil Mika, Sucheewin Krobthong, Kittikhun Kerdsomboon, Supeecha Kumkate, Toemthip Poolpak, Siraprapa Kidhakarn, Kwang Mo Yang, Tossapol Limcharoensuk, Choowong Auesukaree
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37424- (2024)
Cadmium (Cd) is a highly harmful pollutant that poses a serious threat to human health. The liver is the primary organ for Cd accumulation, and Cd-induced hepatotoxicity has been shown to be strongly correlated with an oxidative imbalance in hepatocy
Externí odkaz:
https://doaj.org/article/54ec00a8c0074ca987c606fe71de687a
Autor:
Magdalena Kotańska, Monika Zadrożna, Monika Kubacka, Kamil Mika, Katarzyna Szczepańska, Barbara Nowak, Alessio Alesci, Anthea Miller, Eugenia Rita Lauriano, Katarzyna Kieć-Kononowicz
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 858 (2024)
Background: Numerous studies highlight the critical role that neural histamine plays in feeding behavior, which is controlled by central histamine H3 and H1 receptors. This is the fundamental motivation for the increased interest in creating histamin
Externí odkaz:
https://doaj.org/article/a89f1fff18ba46f69f8f2291d9821f40
Autor:
Kamil Mika, Małgorzata Szafarz, Marek Bednarski, Agata Siwek, Katarzyna Szczepańska, Katarzyna Kieć-Kononowicz, Magdalena Kotańska
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7499 (2023)
Many studies have shown the high efficacy of histamine H3 receptor ligands in preventing weight gain. In addition to evaluating the efficacy of future drug candidates, it is very important to assess their safety profile, which is established through
Externí odkaz:
https://doaj.org/article/bafbc4a9dbc64b9083a1b98e2335fd3a
Autor:
Kamil Mika, Małgorzata Szafarz, Marek Bednarski, Kamil Kuder, Katarzyna Szczepańska, Krzysztof Pociecha, Bartosz Pomierny, Katarzyna Kieć-Kononowicz, Jacek Sapa, Magdalena Kotańska
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 142, Iss , Pp 111952- (2021)
Aims: One of the therapeutic approaches in the treatment of obesity is the use of histamine H3 receptor ligands. Histamine plays a significant role in eating behavior because it causes a loss of appetite and is considered to be a satiety signal relea
Externí odkaz:
https://doaj.org/article/6a3c5ca87e4d48f58209fd85d18e7a2d
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss , Pp 111892- (2021)
It is important to search for a promising therapeutic target or small molecules that can control excessive eating since limiting the intake of foods, especially tasty ones, could be effective in the treatment or prevention of obesity. Some studies in
Externí odkaz:
https://doaj.org/article/8cc6876e60c24acfb9d510e8af751feb
Autor:
Magdalena Kotańska, Anna Dziubina, Małgorzata Szafarz, Kamil Mika, Marek Bednarski, Noemi Nicosia, Ahmed Temirak, Christa E. Müller, Katarzyna Kieć-Kononowicz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13439 (2022)
The adenosine A2A and A2B receptors are promising therapeutic targets in the treatment of obesity and diabetes since the agonists and antagonists of these receptors have the potential to positively affect metabolic disorders. The present study invest
Externí odkaz:
https://doaj.org/article/316b3b0d0d284abda8a9a68a54de9b3e
Autor:
Kamil Mika, Małgorzata Szafarz, Monika Zadrożna, Barbara Nowak, Marek Bednarski, Katarzyna Szczepańska, Krzysztof Pociecha, Monika Kubacka, Noemi Nicosia, Izabela Juda, Katarzyna Kieć-Kononowicz, Magdalena Kotańska
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7011 (2022)
Many studies involving compounds that enhance histamine release, such as histamine H3 receptor (H3R) antagonists, have shown efficacy in inhibiting weight gain, but none have passed clinical trials. As part of the search for H3 receptor ligands that
Externí odkaz:
https://doaj.org/article/2477dbd66c254c70b28533686dafbd71
Autor:
Magdalena Kotańska, Małgorzata Szafarz, Kamil Mika, Anna Dziubina, Marek Bednarski, Christa E. Müller, Jacek Sapa, Katarzyna Kieć-Kononowicz
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 135, Iss , Pp 111164- (2021)
A2B adenosine receptors are present in a wide spectrum of tissues, especially on cells of the immune system. Since these particular receptors have the lowest, of all adenosine receptor subtypes, affinity for adenosine they are believed to play a spec
Externí odkaz:
https://doaj.org/article/42bf36b944a54b8c90fcc8bf52c4c0e7
Autor:
Magdalena Kotańska, Anna Dziubina, Małgorzata Szafarz, Kamil Mika, Karolina Reguła, Marek Bednarski, Małgorzata Zygmunt, Anna Drabczyńska, Jacek Sapa, Katarzyna Kieć-Kononowicz
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0229806 (2020)
The A2 adenosine receptors play an important role, among others, in the regulation of inflammatory process and glucose homeostasis in diabetes and obesity. Thus, the presented project evaluated of influence of the selective antagonist of A2A adenosin
Externí odkaz:
https://doaj.org/article/2d0c6a2ccf8848c79ffcb34e1aaa30e1
Autor:
Kamil Mika, Małgorzata Szafarz, Marek Bednarski, Gniewomir Latacz, Sylwia Sudoł, Jadwiga Handzlik, Krzysztof Pociecha, Joanna Knutelska, Noemi Nicosia, Katarzyna Szczepańska, Kamil J. Kuder, Katarzyna Kieć-Kononowicz, Magdalena Kotańska
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1080 (2021)
Noting the worldwide rapid increase in the prevalence of overweight and obesity new effective drugs are now being sought to combat these diseases. Histamine H3 receptor antagonists may represent an effective therapy as they have been shown to modulat
Externí odkaz:
https://doaj.org/article/4a2cda7eb07b4e9996441514b99f7a6c