Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kamiko R. Bressler"'
Autor:
Joseph A. Ross, Kamiko R. Bressler, Keiran Vanden Dungen, Mikayla Fredriksen, Nirujah Balasingam, Nehal Thakor, Divya Khandige Sharma
Publikováno v:
Cell Death and Disease, Vol 10, Iss 2, Pp 1-15 (2019)
Cell Death & Disease
Cell Death & Disease
Physiological stress conditions attenuate global mRNA translation via modifications of key eukaryotic initiation factors. However, non-canonical translation initiation mechanisms allow cap-independent translation of certain mRNAs. We have previously
Autor:
Keiran Vanden Dungen, Slava Ilnytskyy, Athanasios Zovoilis, Igor Kovalchuk, Nehal Thakor, Kush Patel, Kamiko R. Bressler, Katrina Taylor, Joseph A. Ross
Publikováno v:
Cell Stress Chaperones
During the integrated stress response (ISR), global translation initiation is attenuated; however, noncanonical mechanisms allow for the continued translation of specific transcripts. Eukaryotic initiation factor 5B (eIF5B) has been shown to play a c
Autor:
Kamiko R. Bressler, Donna L. Senger, Bo Young Ahn, Nehal Thakor, Jennifer King, Joseph A. Ross
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 98(6)
Glioblastoma multiforme (GBM) is among the deadliest cancers, owing in part to complex inter- and intra-tumor heterogeneity and the presence of a population of stem-like cells called brain tumour stem cells (BTSCs/BTICs). These cancer stem cells surv
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 12
International Journal of Molecular Sciences, Vol 19, Iss 12, p 4032 (2018)
Volume 19
Issue 12
International Journal of Molecular Sciences, Vol 19, Iss 12, p 4032 (2018)
A variety of cellular stresses lead to global translation attenuation due to phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF2), which decreases the availability of the eIF2-GTP-Met-tRNAi ternary complex. However, a subset
Publikováno v:
Journal of Nucleic Acids
Journal of Nucleic Acids, Vol 2016 (2016)
Journal of Nucleic Acids, Vol 2016 (2016)
Protein synthesis can be segmented into distinct phases comprising mRNA translation initiation, elongation, and termination. Translation initiation is a highly regulated and rate-limiting step of protein synthesis that requires more than 12 eukaryoti