Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kamelia Zerrouki"'
Autor:
A. Clare Sparling, James M. Ward, Kakali Sarkar, Adam Schiffenbauer, Payam Noroozi Farhadi, Michael A. Smith, Saifur Rahman, Kamelia Zerrouki, Frederick W. Miller, Jian-Liang Li, Kerry A. Casey, Lisa G. Rider
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Objectives Serum protein abundance was assessed in adult and juvenile dermatomyositis (DM and JDM) patients to determine differentially regulated proteins, altered pathways, and candidate disease activity biomarkers. Methods Serum protein ex
Externí odkaz:
https://doaj.org/article/5ee387052055449bbf31c595ef8f3253
Autor:
Shu Wang, Jingya Wang, Varsha Kumar, Jodi L. Karnell, Brian Naiman, Phillip S. Gross, Saifur Rahman, Kamelia Zerrouki, Richard Hanna, Christopher Morehouse, Nicholas Holoweckyj, Hao Liu, Autoimmunity Molecular Medicine Team, Zerai Manna, Raphaela Goldbach-Mansky, Sarfaraz Hasni, Richard Siegel, Miguel Sanjuan, Katie Streicher, Michael P. Cancro, Roland Kolbeck, Rachel Ettinger
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Systemic lupus erythematosus (SLE) is associated with altered B cell responses but the underlying aetiology is still unclear. Here the authors show that a CD11chiT-bet+ B cell subset with a unique phenotype and transcriptome is increased in patients
Externí odkaz:
https://doaj.org/article/b12a066bb82147b99f7c7c8fcb7739ef
Autor:
James Ward, Mythri Ambatipudi, Terrance P O'Hanlon, Michael A. Smith, Melissa de Los Reyes, Adam Schiffenbauer, Saifur Rahman, Kamelia Zerrouki, Frederick W. Miller, Miguel A. Sanjuan, Jian‐Liang Li, Kerry A. Casey, Lisa G. Rider
Publikováno v:
Arthritis & Rheumatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18074110a18b25e1e85b244a8f4940c0
https://doi.org/10.1002/art.42615
https://doi.org/10.1002/art.42615
Autor:
Richard M. Siegel, Zerai Manna, William Rees, Adam Schiffenbauer, Wendy I. White, Michael A Smith, Sarfaraz Hasni, Chia-Chien Chiang, Katie Streicher, Kerry A. Casey, Frederick W. Miller, Dominic Sinibaldi, Kamelia Zerrouki, Saifur Rahman, Miguel A. Sanjuan, Mariana J. Kaplan, Lisa G. Rider
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Type I interferon (IFN) drives pathology in systemic lupus erythematosus (SLE) and can be tracked via IFN-inducible transcripts in blood. Here, we examined whether measurement of circulating proteins, which enter the bloodstream from inflamed tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff841eda5f664f6f6eed2e315aa72ea
http://link.springer.com/article/10.1038/s41598-020-60563-9
http://link.springer.com/article/10.1038/s41598-020-60563-9
Autor:
Jingya Wang, Karma Dacosta, Jennifer Cann, Todd Davidson, Georgia Cresswell, Jane Connor, Kamelia Zerrouki, Daphne Macapagal
Multiple sclerosis is a chronic debilitating disease of the CNS. The relapsing remitting form of the disease is driven by CNS directed inflammation. However, in the progressive forms of the disease, inflammation has abated and the underlying patholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4218b4de23b96de942db5e497a98668a
https://doi.org/10.1101/2021.07.06.451298
https://doi.org/10.1101/2021.07.06.451298
Autor:
Jennifer Kearley, Jingya Wang, Kamelia Zerrouki, M.Y. Yang, L. Eldridge, Aaron A Berlin, Jane Connor, R. Dagher, Varsha Kumar, R.N. Hanna, Mahboobe Ghaedi, E. Gubbins, P. Sanders, Annik Migneault, D. Finch, Ximing Xiong, A. Gonzalez, T. Cottage
Publikováno v:
B65. COPD PATHOGENESIS: CELL AND ANIMAL MODELS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b91d7d3b0a72b4c6493a86a3bb0e84ed
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4062
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4062
Autor:
Weiguang Zhao, Ximing Xiong, Roland Kolbeck, G.J. Criner, Kamelia Zerrouki, Charles Brown, Aaron A Berlin, Christopher T. Cottage, Jane Connor, Jennifer Kearley, Raphael Lemaire, Norman C. Peterson, Annik Migneault, Anna Huntley
Publikováno v:
Communications Biology
Communications Biology, Vol 2, Iss 1, Pp 1-11 (2019)
Communications Biology, Vol 2, Iss 1, Pp 1-11 (2019)
Senescence is a mechanism associated with aging that alters tissue regeneration by depleting the stem cell pool. Chronic obstructive pulmonary disease (COPD) displays hallmarks of senescence, including a diminished stem cell population. DNA damage fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e41ac28b4e63c0793ede82c72a7e143
https://doi.org/10.1038/s42003-019-0532-1
https://doi.org/10.1038/s42003-019-0532-1
Autor:
Christopher Morehouse, Sarfaraz Hasni, Jodi L. Karnell, Michael P. Cancro, Kamelia Zerrouki, Miguel Sanjuan, Brian Naiman, Richard N. Hanna, Zerai Manna, Katie Streicher, Rachel Ettinger, Shu Wang, Saifur Rahman, Phillip S. Gross, Roland Kolbeck, Richard M. Siegel, Nicholas Holoweckyj, Varsha Kumar, Raphaela Goldbach-Mansky, Jingya Wang, Hao Liu
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Although the aetiology of systemic lupus erythematosus (SLE) is unclear, dysregulated B cell responses have been implicated. Here we show that an unusual CD11chiT-bet+ B cell subset, with a unique expression profile including chemokine receptors cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a595dc7c3fefba751a7afb0abfca668
https://doi.org/10.1038/s41467-018-03750-7
https://doi.org/10.1038/s41467-018-03750-7
Autor:
Erika Farmer, Kamelia Zerrouki, Inna Vainshtein, Meina Liang, Jeffrey M. Riggs, Bhargavi Rajan, Chris Morehouse, Kevin Schifferli, Kimberly Rosenthal, Richard N. Hanna, Divya Sagar, Melissa de los Reyes, Roland Kolbeck, Miguel A. Sanjuan, Gary P. Sims, Jodi L. Karnell
Publikováno v:
Lupus Science & Medicine
Objective We investigated the mechanistic and pharmacological properties of anifrolumab, a fully human, effector-null, anti-type I interferon (IFN) alpha receptor 1 (IFNAR1) monoclonal antibody in development for SLE. Methods IFNAR1 surface expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fa428a324c906d6d44a467974ace77
https://doi.org/10.1136/lupus-2018-000261
https://doi.org/10.1136/lupus-2018-000261
Autor:
Michael Alexander Smith, Chia-Chien Chiang, Dominic Sinibaldi, Kamelia Zerrouki, Zerai Manna, Wendy I. White, Mariana J. Kaplan, Sarfaraz Hasni, Richard M. Siegel, Miguel A. Sanjuan, Kerry A. Casey
Publikováno v:
The Journal of Immunology. 198:210.1-210.1
Type I interferon (IFN) signaling drives pathology in systemic lupus erythematosus (SLE) and can be tracked via IFN-inducible transcripts present in whole blood as described by several IFN gene signatures. As SLE is a complex disease affecting divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1100d257d5f5e7b48fe235af983b1a24
https://doi.org/10.4049/jimmunol.198.supp.210.1
https://doi.org/10.4049/jimmunol.198.supp.210.1