Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kamelia M. Amin"'
Autor:
Kamelia M. Amin, Ossama M. El-Badry, Doaa E. Abdel Rahman, Magda H. Abdellattif, Mohammed A. S. Abourehab, Mahmoud H. El-Maghrabey, Fahmy G. Elsaid, Mohamed A. El Hamd, Ahmed Elkamhawy, Usama M. Ammar
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1954 (2022)
Inhibition of PDE5 results in elevation of cGMP leading to vascular relaxation and reduction in the systemic blood pressure. Therefore, PDE5 inhibitors are used as antihypertensive and antianginal agents in addition to their major use as male erectil
Externí odkaz:
https://doaj.org/article/5f25561b2fb14338b850b5a5cdc235a1
Autor:
Zinab M. Nofal, Kamelia M. Amin, Hanaa S. Mohamed, Ahmed M. El-Kerdawy, Magdy S. Aly, Basma S. Habib, Alaadin E. Sarhan
Publikováno v:
Synthetic Communications. 52:1805-1824
Publikováno v:
ChemistrySelect. 4:8882-8885
Autor:
Yasmin M. Syam, Tamer M. Abdel-Ghani, Manal M. Anwar, Aya M. Serry, Kamelia M. Amin, Hamed I. Ali
Publikováno v:
Bioorganic Chemistry. 76:487-500
This study deals with synthesis of a new set of benzofuran and 5H-furo[3,2-g]chromone linked various heterocyclic functionalities using concise synthetic approaches aiming to gain new antiproliferative candidates against MCF-7 breast cancer cells of
Publikováno v:
Journal of Advanced Pharmacy Research. 1:216-227
Three series of ring-equivalent tricyclic benzo[h]quinazolines, benzo[h]quinolines and naphthaleno[d]thiazoles analogs were designed as bioisosteres and synthesized. The chemical structures of the synthesized agents were elucidated based on their spe
Autor:
Yasmin M. Syam, Manal M. Anwar, Aya M. Serry, Tamer M. Abdel-Ghani, Hamed I. Ali, Kamelia M. Amin
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:2423-2436
Based on the reported high expression of p38α MAP kinase in invasive breast cancers and the activity of different functionalized chromone derivatives as p38α inhibitors, a new set of 4,9-dimethoxy/4-methoxy-7-methyl-5-oxo-5 H -furo[3,2- g ]chromone
Publikováno v:
Future medicinal chemistry. 11(7)
A series of new visnagin and benzofuran scaffold-based molecules was designed and synthesized as anti-inflammatory and analgesic agents. Biological screening of these compounds showed that they exhibit potent anti-inflammatory/analgesic activity with
Publikováno v:
European Journal of Chemistry. 7:19-29
Design and synthesis of some new pyridopyrazinone derivatives as anti-proliferative agents is described. The cytotoxic activities of the synthesized compounds against melanoma cell line (LOXIMVI), ovarian cell line (OVCAR3), thyroid cell lines (CAL62
Publikováno v:
Research on Chemical Intermediates. 41:2537-2555
A new series of derivatives bearing benzothiazol-2-one or benzothiazole ring system conjugated to other different heterocycles were prepared using 5,6-dimethoxy-3-benzothiazol-2(3H)-one (1) as a starting material. The structures of the newly synthesi
Publikováno v:
Research on Chemical Intermediates. 40:847-869
A series of new compounds bearing a 1,3-benzothiazol-2-one nucleus have been synthesized using 5,6-dimethyl-3-(2-oxo-propyl)-1,3-benzothiazol-2-one (1) as a key starting compound. The reaction of 1 with some nucleophilic compounds led to the formatio