Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Kamel Mabrouk"'
Autor:
Magali Casanova, Marc Maresca, Isabelle Poncin, Vanessa Point, Hamza Olleik, Céline Boidin-Wichlacz, Aurélie Tasiemski, Kamel Mabrouk, Jean-François Cavalier, Stéphane Canaan
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-16 (2024)
Abstract Background Mycobacterium abscessus, a fast-growing non-tuberculous mycobacterium, is an emerging opportunistic pathogen responsible for chronic bronchopulmonary infections in people with respiratory diseases such as cystic fibrosis (CF). Due
Externí odkaz:
https://doaj.org/article/4c8949af99094165b508fb3ee240a892
Autor:
Yasmine Boughanmi, Caroline Berenguer-Daizé, Marielle Balzano, Hend Mosrati, Maxime Moulard, Pascal Mansuelle, Patrick Fourquet, Franck Torre, Harold de Pomyers, Didier Gigmes, Lhoucine Ouafik, Kamel Mabrouk
Publikováno v:
Toxins, Vol 16, Iss 10, p 433 (2024)
This study explores the potential of natural bioactive peptides from animal venoms as targeted anti-cancer agents with reduced toxicity. Initially, we screened a broad collection of animal venoms for their antiproliferative activity against cancer ce
Externí odkaz:
https://doaj.org/article/e18b7988f5034890a7a459ffdb0ade88
Autor:
Yasmine Boughanmi, Soioulata Aboudou, Kayané Boyadjian, Acil Charouandi, Sarra Bouzid, Thelma Barnetche, Pascal Mansuelle, Régine Lebrun, Didier Gigmes, Harold de Pomyers, Kamel Mabrouk
Publikováno v:
Separations, Vol 11, Iss 6, p 179 (2024)
Animal venoms are intricate and teem with potential for groundbreaking medical advancements. Although traditional methods for purifying venom proteins are effective, they usually require complicated, multi-step processes that lead to lower yields. Ou
Externí odkaz:
https://doaj.org/article/012948c5f72b4a3e92df2eddc0d089fe
Autor:
Romain Sigaud, Nadège Dussault, Caroline Berenguer-Daizé, Christine Vellutini, Zohra Benyahia, Mylène Cayol, Fabrice Parat, Kamel Mabrouk, Ramiro Vázquez, Maria E. Riveiro, Philippe Metellus, L’Houcine Ouafik
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
VE-cadherin is an essential adhesion molecule in endothelial adherens junctions, and the integrity of these complexes is thought to be regulated by VE-cadherin tyrosine phosphorylation. We have previously shown that adrenomedullin (AM) blockade corre
Externí odkaz:
https://doaj.org/article/213926a4514e458da5ff6110a8a97da0
Autor:
María Cecilia González García, Caroline Radix, Claude Villard, Gilles Breuzard, Pascal Mansuelle, Pascale Barbier, Philipp O. Tsvetkov, Harold De Pomyers, Didier Gigmes, François Devred, Hervé Kovacic, Kamel Mabrouk, José Luis
Publikováno v:
Molecules, Vol 27, Iss 23, p 8241 (2022)
Microtubule targeting agents (MTA) are anti-cancer molecules that bind tubulin and interfere with the microtubule functions, eventually leading to cell death. In the present study, we used an in vitro microtubule polymerization assay to screen severa
Externí odkaz:
https://doaj.org/article/5bea319f2fbc48778fcfb4e4890aebd3
Autor:
Quentin Coquerel, Claire Legendre, Jacinthe Frangieh, Stephan De Waard, Jérôme Montnach, Leos Cmarko, Joseph Khoury, Charifat Said Hassane, Dimitri Bréard, Benjamin Siegler, Ziad Fajloun, Harold De Pomyers, Kamel Mabrouk, Norbert Weiss, Daniel Henrion, Pascal Richomme, César Mattei, Michel De Waard, Anne-Marie Le Ray, Christian Legros
Publikováno v:
Molecules, Vol 27, Iss 13, p 4133 (2022)
Voltage-gated Na+ (NaV) channels are significant therapeutic targets for the treatment of cardiac and neurological disorders, thus promoting the search for novel NaV channel ligands. With the objective of discovering new blockers of NaV channel ligan
Externí odkaz:
https://doaj.org/article/3c3824003c5c472796fb3122b1c94452
Autor:
Léa Réthoré, Joohee Park, Jérôme Montnach, Sébastien Nicolas, Joseph Khoury, Elodie Le Seac’h, Kamel Mabrouk, Harold De Pomyers, Hélène Tricoire-Leignel, César Mattei, Daniel Henrion, Ziad Fajloun, Michel De Waard, Claire Legendre, Christian Legros
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 827 (2022)
Thanks to the crosstalk between Na+ and Ca2+ channels, Na+ and Ca2+ homeostasis interplay in so-called excitable cells enables the generation of action potential in response to electrical stimulation. Here, we investigated the impact of persistent ac
Externí odkaz:
https://doaj.org/article/57ada7469988481e8614e44ef136cdde
Autor:
Wassim Moslah, Dorra Aissaoui-Zid, Soioulata Aboudou, Zaineb Abdelkafi-Koubaa, Marie Potier-Cartereau, Aude Lemettre, Ines ELBini-Dhouib, Naziha Marrakchi, Didier Gigmes, Christophe Vandier, José Luis, Kamel Mabrouk, Najet Srairi-Abid
Publikováno v:
Molecules, Vol 27, Iss 3, p 806 (2022)
Glioblastoma is the most aggressive and invasive form of central nervous system tumors due to the complexity of the intracellular mechanisms and molecular alterations involved in its progression. Unfortunately, current therapies are unable to stop it
Externí odkaz:
https://doaj.org/article/5da1136e16384cfcb358fe30f370beab
Autor:
Florence Chalier, Laura Mugnier, Marion Tarbe, Soioulata Aboudou, Claude Villard, Hervé Kovacic, Didier Gigmes, Pascal Mansuelle, Harold de Pomyers, José Luis, Kamel Mabrouk
Publikováno v:
Toxins, Vol 12, Iss 2, p 102 (2020)
In the soft treatment of cancer tumours, consequent downregulation of the malignant tissue angiogenesis constitutes an efficient way to stifle tumour development and metastasis spreading. As angiogenesis requires integrin−promoting endothelial cell
Externí odkaz:
https://doaj.org/article/bbc0695cbc1b42cfbbdd47f12f32a5dc
Autor:
Awatef Ouertani, Ines Chaabouni, Amor Mosbah, Justine Long, Mohamed Barakat, Pascal Mansuelle, Olfa Mghirbi, Afef Najjari, Hadda-Imene Ouzari, Ahmed S. Masmoudi, Marc Maresca, Philippe Ortet, Didier Gigmes, Kamel Mabrouk, Ameur Cherif
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Milk and dairy products harbor a wide variety of bacterial species that compete for both limited resources and space. Under these competitive conditions, bacteria develop specialized mechanisms to protect themselves during niche colonization and nutr
Externí odkaz:
https://doaj.org/article/078c703caf0d45efa042b8165b4b405c