Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kamel Lahouel"'
Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer
Autor:
Bahman Afsari, Albert Kuo, YiFan Zhang, Lu Li, Kamel Lahouel, Ludmila Danilova, Alexander Favorov, Thomas A Rosenquist, Arthur P Grollman, Ken W Kinzler, Leslie Cope, Bert Vogelstein, Cristian Tomasetti
Publikováno v:
eLife, Vol 10 (2021)
Determining the etiologic basis of the mutations that are responsible for cancer is one of the fundamental challenges in modern cancer research. Different mutational processes induce different types of DNA mutations, providing ‘mutational signature
Externí odkaz:
https://doaj.org/article/eb75fd97d7114fa0ba902af179400db3
Autor:
Jeanne, Tie, Joshua D, Cohen, Kamel, Lahouel, Serigne N, Lo, Yuxuan, Wang, Suzanne, Kosmider, Rachel, Wong, Jeremy, Shapiro, Margaret, Lee, Sam, Harris, Adnan, Khattak, Matthew, Burge, Marion, Harris, James, Lynam, Louise, Nott, Fiona, Day, Theresa, Hayes, Sue-Anne, McLachlan, Belinda, Lee, Janine, Ptak, Natalie, Silliman, Lisa, Dobbyn, Maria, Popoli, Ralph, Hruban, Anne Marie, Lennon, Nicholas, Papadopoulos, Kenneth W, Kinzler, Bert, Vogelstein, Cristian, Tomasetti, Peter, Gibbs, Susanne, Kosmider
Publikováno v:
New England Journal of Medicine. 386:2261-2272
The role of adjuvant chemotherapy in stage II colon cancer continues to be debated. The presence of circulating tumor DNA (ctDNA) after surgery predicts very poor recurrence-free survival, whereas its absence predicts a low risk of recurrence. The be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a73799f06b69d01e6f302d570bc06b
https://doi.org/10.1056/nejmoa2200075
https://doi.org/10.1056/nejmoa2200075
Autor:
Laurent Younes, Kamel Lahouel, Donald Geman, Bert Vogelstein, Francis M. Giardiello, Ludmila Danilova, John D. Groopman, Kenneth W. Kinzler, Ralph H. Hruban, Cristian Tomasetti
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Recently, investigators have shown that only a few driver gene mutational events appear to be needed for cancer to occur. However, the reason that some mutational events precede others in the same cancer and the explanation for tissue-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec7ccb739ca0d8cf53ec1c98544a7ab
http://europepmc.org/articles/PMC6969520
http://europepmc.org/articles/PMC6969520
Autor:
Samir, LAISSOUF, Kamel, LAHOUEL
Publikováno v:
Journal of Financial, Accounting & Managerial Studies; Dec2022, Vol. 9 Issue 2, p286-301, 16p
Autor:
Jeanne Tie, Joshua Cohen, Kamel Lahouel, Serigne N. Lo, Yuxuan Wang, Rachel Wong, Jeremy David Shapiro, Samuel J. Harris, Muhammad Adnan Khattak, Matthew E. Burge, Marion Harris, James F. Lynam, Louise M. Nott, Fiona Day, Theresa Hayes, Nickolas Papadopoulos, Cristian Tomasetti, Kenneth W. Kinzler, Bert Vogelstein, Peter Gibbs
Publikováno v:
Journal of Clinical Oncology. 40:LBA100-LBA100
LBA100 Background: The role of adjuvant chemotherapy (CT) in stage II colon cancer continues to be debated. The presence of circulating tumor DNA (ctDNA) after surgery predicts very poor recurrence-free survival (RFS), while its absence predicts a lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf39fce6ae23cc05bc94f9783f8a7238
https://doi.org/10.1200/jco.2022.40.17_suppl.lba100
https://doi.org/10.1200/jco.2022.40.17_suppl.lba100
Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer
Autor:
Albert Kuo, Yifan Zhang, Ludmila Danilova, Leslie Cope, Thomas A. Rosenquist, Bert Vogelstein, Alexander V. Favorov, Bahman Afsari, Kenneth W. Kinzler, Kamel Lahouel, Cristian Tomasetti, Lu Li, Arthur P. Grollman
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Determining the etiologic basis of the mutations that are responsible for cancer is one of the fundamental challenges in modern cancer research. Different mutational processes induce different types of DNA mutations, providing ‘mutational signature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e88faf6baadc1e54416c3db66a934f
https://doi.org/10.7554/elife.61082
https://doi.org/10.7554/elife.61082
Autor:
Alexander V. Favorov, Bert Vogelstein, Lu Li, Arthur P. Grollman, Leslie Cope, Thomas A. Rosenquist, Yifan Zhang, Bahman Afsari, Kenneth W. Kinzler, Ludmila Danilova, Albert Kuo, Kamel Lahouel, Cristian Tomasetti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13059fc1778f60cef5398bc7af031467
https://doi.org/10.7554/elife.61082.sa2
https://doi.org/10.7554/elife.61082.sa2
Autor:
Ralph H. Hruban, Kathleen Sheridan, Christoph Lengauer, Andrew Warren, Cristian Tomasetti, Leonardo N. Hagmann, Aalpen A. Patel, Ashley Honushefsky, Christian S. Adonizio, Elliot K. Fishman, Prianka Bhattacharya, Joseph Vadakara, Zachary M. Salvati, Christopher D. Still, Bobbi Urban, Joshua D. Cohen, Anne Marie Lennon, Adam H. Buchanan, Lisa Kann, Chetan Bettegowda, Julie I. Woods, David L. Diehl, Nirav Malani, Rosemary Leeming, David H. Ledbetter, Nickolas Papadopoulos, Hee Jung Hwang, Kamel Lahouel, Isaac Kinde, Fred Sanfilippo, Alison P. Klein, Carroll Walter, Alex Parker, Kenneth W. Kinzler, Shibin Zhou, David D. K. Rolston, Christopher Douville, Dillenia Rosica, Bert Vogelstein, Ariella Cohain
Publikováno v:
Science
A real-time trial of a cancer blood test Cancers diagnosed early are often more responsive to treatment. Blood tests that detect molecular markers of cancer have successfully identified individuals already known to have the disease. Lennon et al. con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817942956ca55b4206be6b73daf9d7f2
https://europepmc.org/articles/PMC7509949/
https://europepmc.org/articles/PMC7509949/
Publikováno v:
Electron. J. Statist. 13, no. 1 (2019), 1292-1328
We analyze control of the familywise error rate (FWER) in a multiple testing scenario with a great many null hypotheses about the distribution of a high-dimensional random variable among which only a very small fraction are false, or "active". In ord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1eb690aba2037660300cae0c2fb2cf
https://doi.org/10.1214/19-ejs1536
https://doi.org/10.1214/19-ejs1536
Publikováno v:
ICASSP
This article introduces and evaluates Sampled Connectionist Temporal Classification (CTC) which connects the CTC criterion to the Cross Entropy (CE) objective through sampling. Instead of computing the logarithm of the sum of the alignment path likel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82e53064794a8122ac2433f604b4c9d8
https://doi.org/10.1109/icassp.2018.8461929
https://doi.org/10.1109/icassp.2018.8461929