The Arabidopsis mTERF‐repeat MDA1 protein plays a dual function in transcription and stabilization of specific chloroplast transcripts within the psbE and ndhH operons

Autor: Rabea Ghandour, Aude Zimmerman, Louis Valentin Méteignier, Jörg Meurer, Abdelmalek Alioua, Karin Meierhoff, Johana Chicher, Reimo Zoschke, Nicolas Baumberger, Kamel Hammani

Publikováno v: New Phytologist
New Phytologist, Wiley, 2020, ⟨10.1111/nph.16625⟩
The New Phytologist

Summary The mTERF gene family encodes for nucleic acid binding proteins that are predicted to regulate organellar gene expression in eukaryotes. Despite the implication of this gene family in plant development and response to abiotic stresses, a prec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2082e9d073039891400150abe5ca898c
https://doi.org/10.1111/nph.16625

In vivo stabilization of endogenous chloroplast RNAs by customized artificial pentatricopeptide repeat proteins

Autor: Alice Barkan, Kamel Hammani, Nikolay Manavski, Sébastien Mathieu, Louis-Valentin Meteignier, Margarita Rojas, Andreas Brachmann

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2020, ⟨10.1093/nar/gkab390⟩
Nucleic Acids Research, Oxford University Press, 2021, 49 (10), pp.5985-5997. ⟨10.1093/nar/gkab390⟩

Pentatricopeptide repeat (PPR) proteins are helical repeat-proteins that bind RNA in a modular fashion with a sequence-specificity that can be manipulated by the use of an amino acid code. As such, PPR repeats are promising scaffolds for the design o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1186e84d57957e0d4489f8d87df2e2
https://hal.archives-ouvertes.fr/hal-03327172/file/islandora_107392.pdf

A PPR protein in the PLS subfamily stabilizes the 5′-end of processedrpl16mRNAs in maize chloroplasts

Autor: Kamel Hammani, Rafael G. Miranda, Mizuki Takenaka, Alice Barkan

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2016, 44 (9), pp.4278-4288

Pentatricopeptide repeat (PPR) proteins are a large family of helical-repeat proteins that bind RNA in mitochondria and chloroplasts. Precise RNA targets and functions have been assigned to only a small fraction of the >400 members of the PPR family

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5151999bf7457c2fa907aa517fa03f1c
https://doi.org/10.1093/nar/gkw270

PPR proteins shed a new light on RNase P biology

Autor: Géraldine Bonnard, Franziska Pinker, Bernard Gutmann, Philippe Giegé, Peter Gegenheimer, Claude Sauter, Kamel Hammani, Anthony Gobert

Publikováno v: RNA Biology

A fast growing number of studies identify pentatricopeptide repeat (PPR) proteins as major players in gene expression processes. Among them, a subset of PPR proteins called PRORP possesses RNase P activity in several eukaryotes, both in nuclei and or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8910f5f27ee7b55909a48d261eff281
https://doi.org/10.4161/rna.25273

An Arabidopsis Dual-Localized Pentatricopeptide Repeat Protein Interacts with Nuclear Proteins Involved in Gene Expression Regulation

Autor: Ian Small, Anthony Gobert, Kamal Hleibieh, Philippe Giegé, Kamel Hammani, Laurence Choulier

Publikováno v: The Plant Cell. 23:730-740

Following the endosymbiotic acquisition of mitochondria by eukaryotic cells, most of the genes in this organelle were transferred to the nucleus. To maintain mitochondrial biogenesis and function, nuclear and mitochondrial genomes require regulated a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c259b91c8e7d0229eb45fab82746496
https://doi.org/10.1105/tpc.110.081638