Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Kamel Benlagha"'
Autor:
Zhennan Han, Kamel Benlagha, Pamela Lee, Chan-Sik Park, Alexander Filatov, Maria G. Byazrova, Heather Miller, Lu Yang, Chaohong Liu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The serine/threonine-specific protein kinases (STKs) are important for cell survival, proliferation, differentiation, and apoptosis. In B cells, these kinases play indispensable roles in regulating important cellular functions. Multiple studies on hu
Externí odkaz:
https://doaj.org/article/5faf3fefb9a346199c6743c862329b93
Autor:
Jia‐Chen Liu, Ke Zhang, Xu Zhang, Fei Guan, Hu Zeng, Masato Kubo, Pamela Lee, Fabio Candotti, Louisa Katherine James, Niels Olsen Saraiva Camara, Kamel Benlagha, Jia‐Hui Lei, Huamei Forsman, Lu Yang, Wei Xiao, Zheng Liu, Chao‐Hong Liu
Publikováno v:
MedComm, Vol 5, Iss 8, Pp n/a-n/a (2024)
Abstract Maturation of the secondary antibody repertoire requires class‐switch recombination (CSR), which switches IgM to other immunoglobulins (Igs), and somatic hypermutation, which promotes the production of high‐affinity antibodies. Following
Externí odkaz:
https://doaj.org/article/b12782f9506642e8a5b259d22218e319
Autor:
Yuanting Yang, Heather Miller, Maria G. Byazrova, Fabio Cndotti, Kamel Benlagha, Niels Olsen Saraiva Camara, Junming Shi, Huamei Forsman, Pamela Lee, Lu Yang, Alexander Filatov, Zhimin Zhai, Chaohong Liu
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTThis review gives an overview of the protective role of CD8+ T cells in SARS-CoV-2 infection. The cross-reactive responses intermediated by CD8+ T cells in unexposed cohorts are described. Additionally, the relevance of resident CD8+ T cells
Externí odkaz:
https://doaj.org/article/6274ace888614234bc4e5f1246f1a414
Autor:
Ludivine Amable, Luis Antonio Ferreira Martins, Remi Pierre, Marcio Do Cruseiro, Ghita Chabab, Arnauld Sergé, Camille Kergaravat, Marc Delord, Christophe Viret, Jean Jaubert, Chaohong Liu, Saoussen Karray, Julien C. Marie, Magali Irla, Hristo Georgiev, Emmanuel Clave, Antoine Toubert, Bruno Lucas, Jihene Klibi, Kamel Benlagha
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Invariant natural killer T (NKT) cell subsets are defined based on their cytokine-production profiles and transcription factors. Their distribution is different in C57BL/6 (B6) and BALB/c mice, with a bias for NKT1 and NKT2/NKT17 subsets, re
Externí odkaz:
https://doaj.org/article/ba78e7ec48c04cffbaafd46f86a85388
Autor:
Kamel Benlagha
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/7d0d10adf0bb4fbfb3e25986058cbcdc
Autor:
Xuying Wang, Fei Guan, Heather Miller, Maria G Byazrova, Fabio Candotti, Kamel Benlagha, Niels Olsen Saraiva Camara, Jiahui Lei, Alexander Filatov, Chaohong Liu
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTThe persistent pandemic of coronavirus disease in 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently poses a major infectious threat to public health around the world. COVID-19 is an infectious di
Externí odkaz:
https://doaj.org/article/579bbf1ae07a4c12ad89ac9e8ac86347
Autor:
Nengqi Lin, Wei Yin, Heather Miller, Maria G. Byazrova, Andrés A. Herrada, Kamel Benlagha, Pamela Lee, Fei Guan, Jiahui Lei, Quan Gong, Youqing Yan, Alexander Filatov, Chaohong Liu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Hepatitis B has become one of the major global health threats, especially in developing countries and regions. Hepatitis B virus infection greatly increases the risk for liver diseases such as cirrhosis and cancer. However, treatment for hepatitis B
Externí odkaz:
https://doaj.org/article/b5022a593b834d1cb9108999e7f763b9
Autor:
Jianing Tang, Lu Yang, Fei Guan, Heather Miller, Niels Olsen Saraiva Camara, Louisa K. James, Kamel Benlagha, Masato Kubo, Steffen Heegaard, Pamela Lee, Jiahui Lei, Hu Zeng, Chengwei He, Zhimin Zhai, Chaohong Liu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Raptor, a key component of mTORC1, is required for recruiting substrates to mTORC1 and contributing to its subcellular localization. Raptor has a highly conserved N-terminus domain and seven WD40 repeats, which interact with mTOR and other mTORC1-rel
Externí odkaz:
https://doaj.org/article/0d328c9cd93a4c8391cd74c645fd80f7
Autor:
Diaoyi Tan, Wei Yin, Fei Guan, Wanjiang Zeng, Pamela Lee, Fabio Candotti, Louisa K James, Niels Olsen Saraiva Camara, S.M. Mansour Haeryfar, Yan Chen, Kamel Benlagha, Lewis Zhichang Shi, Jiahui Lei, Quan Gong, Zheng Liu, Chaohong Liu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
B cells are the core components of humoral immunity. A mature B cell can serve in multiple capacities, including antibody production, antigen presentation, and regulatory functions. Forkhead box P3 (FoxP3)-expressing regulatory T cells (Tregs) are ke
Externí odkaz:
https://doaj.org/article/caf5913442b44c6e8bfedb051d28009b
Autor:
Shiru Chen, Fei Guan, Fabio Candotti, Kamel Benlagha, Niels Olsen Saraiva Camara, Andres A. Herrada, Louisa K. James, Jiahui Lei, Heather Miller, Masato Kubo, Qin Ning, Chaohong Liu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
B cells secrete antibodies and mediate the humoral immune response, making them extremely important in protective immunity against SARS-CoV-2, which caused the coronavirus disease 2019 (COVID-19) pandemic. In this review, we summarize the positive fu
Externí odkaz:
https://doaj.org/article/2e91db76813647e8b8fa138b1dc2533b