Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kamel A Al-Ghareeb"'
Publikováno v:
Suez Canal University Medical Journal. 19:17-28
Background: Treatment of Klebsiella pneumoniae (K. pneumoniae) infections has become very difficult especially in the last decades as the levels of antibiotic resistance are becoming increasingly a serious problem throughout the world. Aim: The growi
Autor:
Augusto C. Ochoa, Jeffrey Wang, Moselhy S Mansy, Kamel A Al-Ghareeb, Kusma Pyakurel, Amir A. Al-Khami, A. Hamid Boulares, Amarjit S. Naura, Salome V. Ibba, Paulo C. Rodriguez, Hamada F. Rady, Ali H. El-Bahrawy, Matthew R. Lammi, Alistair J. Ramsay, Mohamed A. Ghonim
Publikováno v:
Journal of Translational Medicine
Background An important portion of asthmatics do not respond to current therapies. Thus, the need for new therapeutic drugs is urgent. We have demonstrated a critical role for PARP in experimental asthma. Olaparib, a PARP inhibitor, was recently intr
Autor:
Augusto C. Ochoa, Amarjit S. Naura, Moselhy S Mansy, Dorota Wyczechowska, Mohamed A. Ghonim, Samuel C. Okpechi, Matthew R. Lammi, A. Hamid Boulares, Kusma Pyakurel, Salome V. Ibba, Jeffrey Wang, Hogyoung Kim, Paulo C. Rodriguez, Arnold H. Zea, Amir A. Al-Khami, Kamel A Al-Ghareeb, Christian Davis
Publikováno v:
Clinical Science (London, England : 1979)
The present study establishes poly(ADP-ribose)polymerase's (PARP's) role in chronic asthma, demonstrates that it is activated in human asthma, increases the clinical relevance of targeting PARP for blocking or preventing chronic asthma in humans and