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pro vyhledávání: '"Kambiz Amdjadi"'
Publikováno v:
Virology. 297(2):281-288
Herpesvirus saimiri (HVS) of subgroup C efficiently induces leukemia in New World primates and transforms human lymphocytes. The viral tyrosine kinase interacting protein (Tip) binds to the tyrosine protein kinase Lck and is essential for transformat
Autor:
Peter G. Medveczky, Bartholomew M. Sefton, David A. Hartley, Kambiz Amdjadi, Tamara R. Hurley, Troy C. Lund
Publikováno v:
Virology. 276(2):339-348
The Tip protein of Herpesvirus saimiri strain 484C binds to and activates the Lck tyrosine protein kinase. Two sequences in the Tip protein were previously shown to be involved in binding to Lck. A proline-rich region, residues 132–141, binds to th