Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Kambhampati V. B. Rao"'
1
Synthesis of the Pyrido[4,3-D]pyrimidine Congeners of Inosine and of Adenosine - A New Class of 6:6 Bicyclic C-Ribofuranosides
Autor: Mallela S. P. Sarma, Kambhampati V. B. Rao, Robyn S. Klein, Brian A. Otter
Publikováno v: Nucleosides and Nucleotides. 11:61-83
The synthesis of the pyrido[4,3-d]pyrimidine congeners (7 and 8) of inosine and adenosine from the known precursor 3-dimethylamino-2-(2,3-0-isopropylidene-5–0-trityl-D-ribofuranosyl)acrylonitrile (10) is described. The synthetic sequence involves a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b1d8e867bcf7d0e90116fabbdee76fb
https://doi.org/10.1080/07328319208021153
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2
A new synthesis of 3-(β-D-ribofuranosyl)uracil (isouridine)via the intermediacy of an O6,5′-cyclotetrahydropyrimidinone nucleoside
Autor: James A. Kelley, Kambhampati V. B. Rao, Mary T. Corcoran, Victor E. Marquez
Publikováno v: J. Chem. Soc., Perkin Trans. 1. :127-130
A specific and efficient synthesis for 3-(β-D-ribofuranosyl)uracil, isouridine (1), has been devised. Starting with the easily accessible 1-(β-D-ribofuranosyl)-1,2-dihydropyrimidin-2-one (3b) the C-6 carbonyl function of isouridine was built via fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f83deb254a507c8dd8654080b8bb855d
https://doi.org/10.1039/p19830000127
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3
Nucleosides 137. Synthetic Modifications at the 2′Position of Pyrrolo[3,2-D]Pyrimidine and Thieno[3,2-D]Pyrimidine C-Nucleosides, Synthesis of '2′-Deoxy-9-Deazzadenosine' and of '9-Deaza ARA-A'
Autor: Robyn S. Klein, Joseph H. Burchenal, Wa-Yun Ren, Kambhampati V. B. Rao
Publikováno v: Nucleosides and Nucleotides. 5:539-569
The syntheses and preliminary biological evaluation of several novel pyrrolo[3,2-d]pyrimidine and thieno[3,2-d]pyrimidine C-nucleosides incorporating the arabinofuranosyl or 2′-deoxyribofuranosyl sugar moiety are described. The 2′-deoxy thieno[3,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82559a43d8b9e765b1dbe6d30f92eed0
https://doi.org/10.1080/07328318608068696
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5
C-glycosylation of substituted heterocycles under Friedel-Crafts conditions (I): a two-step synthesis of the thieno[3,4-]pyrimidine c-nucleoside analog of inosine
Autor: Kambhampati V. B. Rao, Robert S. Klein, Sunkada P Rao, Brian A. Otter, Wu-Yun Ran
Publikováno v: Tetrahedron Letters. 29:3537-3540
Direct stannic chloride catalyzed C-glycosylation of N-formyl-4-amino-3-carboalkoxy thiophenes with 1- O -acetyl-tri- O -benzoyl-β- D -ribofuranose, followed by annelation of a fused pyrimidone ring upon treatment with ammonia, constitutes a short a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::472db2f241b6b35c2b7a9138e9dd2804
https://doi.org/10.1016/0040-4039(88)85286-9
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6
Convenient synthesis of substituted 3-aminothiophene-2-carbonitriles from α-acetylenic nitriles and their conversion to thieno[3,2-d]pyrimidines
Autor: Robert S. Klein, Kambhampati V. B. Rao, Wu-Yun Ren
Publikováno v: Journal of Heterocyclic Chemistry. 23:1757-1763
Several novel 2,4,6-trisubstituted thieno[3,2-d]pyrimidines were synthesized from the hitherto unknown 3-amino-5-methyl-(or 5-phenyl)thiophene-2-carbonitriles 7 and 8. o-Aminonitriles 7 and 8 were obtained in a single step by conjugate addition of me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6fcefc7c0b4f30f8404106c7a635fd57
https://doi.org/10.1002/jhet.5570230631
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