Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kamau Pierre"'
Publikováno v:
Critical Reviews in Biomedical Engineering. 44:177-191
In this short review, we discuss evidence supporting the modulation of peripheral circadian systems as a therapeutic strategy for rheumatoid arthritis (RA). We first review the role of proinflammatory cytokines and oxidative stress, two of the primar
Autor:
Clara Hartmanshenn, Kamau Pierre, Seul-A Bae, Ioannis P. Androulakis, Rohit Rao, Megerle L. Scherholz, Alison Acevedo
Breakthroughs in high-throughput technologies have provided vast information related to the genome, transcriptome, proteome, and metabolome that enable human physiology to be described mathematically. The collection of biological data at various orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9b93e4c64f803c90602cb04708a0e6f
https://doi.org/10.1016/b978-0-444-63964-6.00001-5
https://doi.org/10.1016/b978-0-444-63964-6.00001-5
Publikováno v:
Endocrinology. 159(4)
Synchronization of biological functions to environmental signals enables organisms to anticipate and appropriately respond to daily external fluctuations and is critical to the maintenance of homeostasis. Misalignment of circadian rhythms with enviro
Publikováno v:
Journal of biological rhythms. 32(5)
Cortisol dynamics are governed by the integration of influences from the suprachiasmatic nucleus (SCN), the hypothalamic-pituitary-adrenal (HPA) axis, and metabolic enzymes, such as the 11β–hydroxysteroid dehydrogenase (HSD) family, which are high
Autor:
Lore Gruenbaum, Timothy R. Wagenaar, Kamau Pierre, Carissa L. Young, Lin Lin, Joshua F. Apgar, Spyros K. Stamatelos, Christian Hotz
Publikováno v:
Cancer Research. 79:685-685
Despite the success of checkpoint blockade immunotherapy, most patients do not respond adequately to treatment and tumors effectively evade T lymphocyte and Natural Killer (NK) cell immune surveillance. Within the tumor microenvironment, the activiti
Publikováno v:
Annals of biomedical engineering. 44(11)
We combine optical scatter imaging with principal component analysis (PCA) to classify apoptosis-competent Bax/Bak-expressing, and apoptosis resistant Bax/Bak-null immortalized baby mouse kidney cells. We apply PCA to 100 stacks each containing 236 d
Publikováno v:
Physiological genomics. 48(10)
Seasonal changes in environmental conditions are accompanied by significant adjustment of multiple biological processes. In temperate regions, the day fraction, or photoperiod, is a robust environmental cue that synchronizes seasonal variations in ne
Autor:
Kamau Pierre, Jennifer A. Hostettler, Nada N. Boustany, M. A. Naser, Michelle T. Graham, Heidy Sierra
Publikováno v:
Biomedical Optics 2014.
We investigate the role of Bax/Bak in altering the morphology of iBMK cells under baseline and apoptosis conditions. Bax/Bak-null cells have more predictable structure measured with entropy textural features of time-lapse optical scatter images.