Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kamau Fahie"'
Autor:
Fiddia Zahra, Gerald W. Hart, Russell A. Reeves, Steve M. Fernandes, Natasha E. Zachara, Kamau Fahie, Bhargavi Narayanan
Publikováno v:
Curr Protoc
O-GlcNAc is a common post-translational modification of nuclear, mitochondrial, and cytoplasmic proteins that regulates normal physiology and the cell stress response. Dysregulation of O-GlcNAc cycling is implicated in the etiology of type II diabete
Publikováno v:
Comprehensive Glycoscience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::951307033db77b55817dc0d169f1def2
https://doi.org/10.1016/b978-0-12-819475-1.00091-2
https://doi.org/10.1016/b978-0-12-819475-1.00091-2
Autor:
Kamau Fahie, Natasha E. Zachara
Publikováno v:
Journal of Molecular Biology. 428:3305-3324
Glycoconjugates, glycans, carbohydrates, and sugars: these terms encompass a class of biomolecules that are diverse in both form and function ranging from free oligosaccharides, glycoproteins and proteoglycans, to glycolipids that make up a complex g
Autor:
Chenxu Guo, Kamau Fahie, Robert N. O'Meally, Natasha E. Zachara, Cathrine McKen, Jennifer Groves, Robert N. Cole, Austin Maduka, Marissa Martinez
Publikováno v:
The FASEB Journal. 32
Autor:
Kamau Fahie, Isabelle Beau, Audrey Esclatine, Magali Chaumorcel, Yolaine Cavignac, Lina Mouna, Jacqueline Cotte-Laffitte, Adam P. Geballe, Patrice Codogno, Wolfram Brune, Marion Lussignol
Publikováno v:
Journal of Virology. 86:2571-2584
Human cytomegalovirus modulates macroautophagy in two opposite directions. First, HCMV stimulates autophagy during the early stages of infection, as evident by an increase in the number of autophagosomes and a rise in the autophagic flux. This stimul
Publikováno v:
FEBS Journal. 276:7159-7176
Endogenous mono-ADP-ribosylation in eukaryotes is involved in regulating protein synthesis, signal transduction, cytoskeletal integrity, and cell proliferation, although few cellular ADP-ribosyltransferases have been identified. The sirtuins constitu
Publikováno v:
The FASEB Journal. 29
Ischemic heart disease causes global morbidity and mortality. Therapies for treating myocardial infarction and ischemia reperfusion injury (IR/I) have remained elusive. Current research demonstrate...
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 19:821-837
The helix-loop-helix (i.e., EF-hand) Ca(2+) ion binding motif is characteristic of a large family of high-affinity calcium ion binding proteins, including the parvalbumins, oncomodulins and calmodulins. In this work we describe a set of molecular dyn
Publikováno v:
The FASEB Journal. 28
The modification of intracellular proteins by monosaccharides of O-linked β-N-acetylglucosamine (O-GlcNAc) has emerged as a regulator of cytoprotection. In response to cellular stress and injury, O...
Autor:
Kevin M. Haigis, David M. Valenzuela, Margaret Karow, Leonard Guarente, Cynthia Wolberger, Kamau Fahie, Gil Blander, Danos C. Christodoulou, Richard Weindruch, Frederick W. Alt, Tomas A. Prolla, Marcia C. Haigis, Andrew J. Murphy, George D. Yancopoulos, Raul Mostoslavsky
Publikováno v:
Cell. 126(5)
SummarySir2 is an NAD-dependent deacetylase that connects metabolism with longevity in yeast, flies, and worms. Mammals have seven Sir2 homologs (SIRT1–7). We show that SIRT4 is a mitochondrial enzyme that uses NAD to ADP-ribosylate and downregulat