Feasibility of comparing medical management and surgery (with neurosurgery or stereotactic radiosurgery) with medical management alone in people with symptomatic brain cavernoma – protocol for the Cavernomas: A Randomised Effectiveness (CARE) pilot trial

Autor: Khalid Hamandi, Julie Woodfield, Smriti Agarwal, Richard Edwards, John Williamson, Ravindran Visagan, Rustam Al-Shahi Salman, Howard Brydon, Diederik Bulters, Dawn Hennigan, Paul Leach, Conor Mallucci, Nitin Mukerji, Marios Papadopoulos, Nicholas Ross, Martin Tisdall, Carole Turner, Shungu Ushewokunze, Raghu Vindlacheruvu, Paul Brennan, Phil White, Sophie Hunter, Karen Coy, Julia Wade, James Stewart, Tom Hughes, Laura Forsyth, Kirsty Harkness, David White, Rupal Shah, Sanjay Bhate, Neil Kitchen, Peter J Hutchinson, Emanuel Cirstea, Ramesh Nair, Rebecca Hall, Varduhi Cahill, Tom Hayton, Silvia Tarantino, Christin Eltze, Jack Lee, Arlo Whitehouse, Daniel Walsh, Jacqueline Stephen, Nicola Phillips, Steff Lewis, Susan Davies, Mathew Guilfoyle, Peter S Hall, Andrew Stoddart, Francesca Colombo, Emma Richards, Greg James, Sarah Illingworth, William B Lo, Andrew Bacon, Vijeya Ganesan, Sabina Patel, Aileen R Neilson, Felicia Jennings, Saba Raza-Knight, Andrew Brodbelt, Aswin Chari, Hasan Asif, Ian Kamaly-Asl, Milan Makwana, Zubair Tahir, Allan MacRaild, Grace Vassallo, Ian Anderson, Daniel Holsgrove, Carole Chambers, Sandra Williams, Francesca Spickett-Jones, Marios C Papadopoulos, John Preston, Edward White, Adel Helmy, Sarah Ali, John Reid, Daniel Brown, Louis Taylor, Christopher Uff, Patrick Grover, Azra Banaras, Linetty Makawa, Anil Israni, Richard J Edwards, William Muirhead, Daniel Brooks, Debbie Brown, Ciaran Scott Hill, Kerry Smith, Beth Atkinson, Michelle Fawcett, Sifelani Tshuma, Oliver Kennion, Jo Howe, James J M Loan, Philip Clatworthy, Claire Hudson, Rebecca Hodnett, Madalina Roman, Mary Sikaonga, Elaine Kinsella, Mario Teo, Venetia Giannakaki, James Loan, Lauren Harris, Jack Wildman, Emmanuel Chavredakis, Nihal Gurusinghe, Alex Rossdeutsch, Anthony Wiggins, Giannis Sokratous, Lucie Ferguson, Shakeelah Patel, Sonia Raj, Oishik Raha, Janneke van Beijnum, Pragnesh Bhatt, Anna Bjornson, Nicole Broomes, Alistair Bullen, Julian Cahill, Mihai Danciut, Ronneil Digpal, Ioannis Fouyas, Lauren S Harris, Sohail Majeed, Matthias Radatz, Oliver Wroe Wright, Jessica Teasdale, Michelle Coakley, Drahoslav Sokol, Chandru Kaliaperumal, Mairi MacDonald, Sarah Risbridger, Siobhan Kearney, Ellaine Bosetta, Thomas Doke, Sonny Coskuner, Christine Kamara, Jonathan Gardner, Imron Hamina, Kishor Chaudhari, Liliana Chapas, Karen Caldwell, Sarah Holland, Tamara Tajsic, Rachael Dore, Taya Anderson, Shelley Mayor, Laura O'Malley, Samantha Glover, Janice Irvine, Annika Walch, Farah Muir, Eng Tah Goh, Andrew McDarby, Michelle Bates, Rebecca Hancox, Claudia Kate Auyeung, Elizabeth Goff, Deanna Stephens, Borislava Borislavova, Ruth Worner, Sandeep Buddha, Lisa Tucker, Sandra Dymond, Andrew Mallick, Dymona McAleer, Belinda Gunning, Emma Clarkson, Cathy Stoneley, Jibril Osman Farah, Niamh Bohnacker, Rosette Marimon, Lydia Parker, Puneet Sharma, Dan Holsgrove, Danielle McLaughlan, Tracey Marsden, Kathryn Cawley, Hellen Raffalli, Imedla Mayor, Dipek Ram, Rebecca Keeping, Katie Hennessy, Ammar Kadhim, Md Moidul Islam, Manjunath Prasad, Cheryl Webster, Vicky Slater, Saffnan Mohamed, Saba Raza Knight, Terri-Louise Cromie, Allan Brown, Ruth Pennington, Charlene Campbell, Anthony Ghosh, Teresa Fitzpatrick, Mohammed Patel, Winnington Ruiz, Mirriam Taylor, Divina Anyog, Katarzyna Tluchowska, Jackson Nolasco, Kleopatra Angelopoulou, Bethany Welch, Ida Ponce, Lucy Bailey, Mia Marsden, Angelene Cope, Deepthy Blesson, Rachel Sutton, Mary Kambafwile, Jade McAndrew

Publikováno v: BMJ Open, Vol 13, Iss 8 (2023)

Introduction The top research priority for cavernoma, identified by a James Lind Alliance Priority setting partnership was ‘Does treatment (with neurosurgery or stereotactic radiosurgery) or no treatment improve outcome for people diagnosed with a

Externí odkaz: https://doaj.org/article/df389aa5a29f4557ac19c817e505e753

A retrospective regional study of aqueduct stenosis and fourth ventricle outflow obstruction in the paediatric complex neurofibromatosis type 1 population; Aetiology, clinical presentation and management

Autor: Murphy, Christopher ^*, Vassallo, Grace, Burkitt-Wright, Emma, Hupton, Eileen, Eelloo, Judith, Lewis, Lauren, Huson, Susan, Stivaros, Stavros, Kamaly-Asl, Ian

Publikováno v: In Clinical Neurology and Neurosurgery June 2020 193

Evaluating the role of practical skills assessments in the UK neurosurgical national selection process

Autor: T. Grundy, T. Fallows, P. Whitfield, I. Kamaly-Asl

Publikováno v: Brain and Spine, Vol 2, Iss , Pp 101386- (2022)

Externí odkaz: https://doaj.org/article/fea3f6166884487ea2fc6d200779aad0

UK Chiari 1 Study: protocol for a prospective, observational, multicentre study

Autor: Joseph Merola, Julie Woodfield, Linda D’Antona, Richard Edwards, Jothy Kandasamy, Paul Leach, Mano Shanmuganathan, Saurabh Sinha, Dominic Thompson, Lewis Thorne, Ahmed Toma, Shungu Ushewokunze, Laurence Watkins, James Stewart, Angelos G Kolias, Jayaratnam Jayamohan, Pasquale Gallo, Navneet Singh, Ashwin Kumaria, Rhannon Lobo, Marianne Hare, Louise Young, Ardalan Zolnourian, Rory J Piper, Daniel Thompson, Greg James, Georgios Tsermoulas, Rosa Sun, William B Lo, Wai Cheong Soon, Babar Vaqas, Muhammad Kamal, Fardad T Afshari, Edward W Dyson, Rodney Laing, Aabir Chakraborty, Adrian Casey, Adriana Baritchii, Alexandros Vyziotis, Ali Nader-Sephai, Alistair Jenkins, Amin Andalib, Anan Shtaya, Andrew Alalade, Andrew Brodbelt, Arup Ray, Asfand Baig Mirza, Aswin Chari, Barrie White, Benedetta Pettorini, Chandrasekaran Kaliaperumal, Danyal Khan, Dardis Ronan, David Choi, David Rowland, Edward Jerome St George, Eleni Maratos, Grainne McKenna, Hani Marcus, Hasan Asif, Hugo Layard Horsfall, Ian Kamaly-Asl, Ibrahim Jalloh, Jawad Naushahi, Joe M Das, John Duddy, Jonathan Funnell, Justyna Ekert, Kevin Tsang, Lizkerry Odeh, Makinah Haq, Mansoor Foroughi, Mark Nowell, Matthew Boissaud-Cooke, Melissa Gough, Menaka Paranathala, Micaela Uberti, Michael Cearns, Milan Makwana, Milo Hollingworth, Ming Yao Chong, Musa China, Nadia Salloum, Nicholas Haden, Nikolaos Tzerakis, Oscar MacCormac, Peter McGarrity, Rudrajit Kanjilal, Ryan Waters, Saeed Kayhanian, Samuel Jeffery, Setthasorn Zhi Yang Ooi, Shabin Joshi, Shady Elsayed, Shafqat Bukhari, Shailendra Magdum, Siddharth Sinha, Simon Lammy, Stana Bojanic, Stewart Griffiths, Teresa Scott, Thomas Carroll, Vasileios Raptopoulos, Vivek Josan, Yasir Chowdhury, Zubair Tahir

Publikováno v: BMJ Open, Vol 11, Iss 4 (2021)

Introduction Chiari 1 malformation (CM1) is a structural abnormality of the hindbrain characterised by the descent of the cerebellar tonsils through the foramen magnum. The management of patients with CM1 remains contentious since there are currently

Externí odkaz: https://doaj.org/article/c333412a84964f27b1b683d8d73f4b44

Cutaneous vascular structure and perfusion in patients with chronic plaque psoriasis

Autor: Andrea Luengas-Martinez, Anna Kamaly-Asl, Iskander H Chaudhry, Paul E C Brenchley, Helen S Young

Publikováno v: Clinical and Experimental Dermatology. 48:181-187

BackgroundVascular dysfunction is a significant contributor to the pathophysiology of psoriasis. Some individuals have variation within the gene for vascular endothelial growth factor-A (VEGF-A), which confers an increased risk of developing psoriasi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c5afaf5b524622a6889d02cbcb5b27fe
https://doi.org/10.1093/ced/llac047