Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kamalaveni R. Prabakar"'
Autor:
Kamalaveni R. Prabakar, Juan Domínguez-Bendala, R. Damaris Molano, Antonello Pileggi, Susana Villate, Camillo Ricordi M.D., Luca Inverardi
Publikováno v:
Cell Transplantation, Vol 21 (2012)
We sought to assess the potential of human cord blood-derived mesenchymal stem cells (CB-MSCs) to derive insulin-producing, glucose-responsive cells. We show here that differentiation protocols based on stepwise culture conditions initially described
Externí odkaz:
https://doaj.org/article/1ec4eb5742b14cb385b4c2cd1b72e0a5
Autor:
Giacomo Lanzoni, Maria Boulina, Camillo Ricordi, Ricardo L. Pastori, Juan Domínguez-Bendala, Nancy Vargas, Luca Inverardi, Dagmar Klein, Kamalaveni R. Prabakar, Silvia Álvarez-Cubela
Publikováno v:
Diabetes
The exocrine pancreas can give rise to endocrine insulin-producing cells upon ectopic expression of key transcription factors. However, the need for genetic manipulation remains a translational hurdle for diabetes therapy. Here we report the conversi
Autor:
Alberto Pugliese, Roy G. Smith, Jessica M. Schrunk, Carol Vinton, Zoe Loomis, Kamalaveni R. Prabakar, Keith R. Anderson, Michelle L. Doyle, Yuxian Sun, Teresa L. Mastracci, Lori Sussel, Jonathon T. Hill, Angela Minic
Publikováno v:
Regulatory Peptides. 157:51-56
Ghrelin is a peptide hormone that has been implicated in the regulation of food intake and energy homeostasis. Ghrelin is predominantly produced in the stomach, but is also expressed in many other tissues where its functions are not well characterize
Autor:
Ulf Dahl, Juan Diez, Alberto Pugliese, Camillo Ricordi, Douglas Hanahan, Markus Zeller, Eliot Rosenkranz, Armando J. Mendez, Gloria Allende, Carlos A. Garcia, Rajpreet Dogra, Zhu Alexander Cao, Kamalaveni R. Prabakar
Publikováno v:
Scopus-Elsevier
The natural expression of tissue-specific genes in the thymus, e.g., insulin, is critical for self-tolerance. The transcription of tissue-specific genes is ascribed to peripheral Ag-expressing (PAE) cells, which discordant studies identified as thymi
Autor:
Antonello Pileggi, Susana Villate, Luca Inverardi, Camillo Ricordi, R. Damaris Molano, Kamalaveni R. Prabakar, Juan Domínguez-Bendala
Publikováno v:
Cell Transplantation, Vol 21 (2012)
We sought to assess the potential of human cord blood-derived mesenchymal stem cells (CB-MSCs) to derive insulin-producing, glucose-responsive cells. We show here that differentiation protocols based on stepwise culture conditions initially described
Autor:
Alberto Pugliese, P. Vaidyanathan, John C. Hutton, K. E. Marshall, Kamalaveni R. Prabakar, Rajpreet Dogra
Publikováno v:
Diabetologia. 49(5)
Autoimmunity to insulin, glutamic acid decarboxylase and the tyrosine-phosphatase-like protein IA-2 is associated with type 1 diabetes. The production of self-molecules in thymus and secondary lymphoid tissues is critical for self-tolerance; reduced
Publikováno v:
Current diabetes reports. 4(2)
Studies in both humans and rodent models provide new insight into key mechanisms regulating tolerance to self-molecules. There is evidence that tissue-specific molecules are expressed in the thymus and peripheral lymphoid tissues (PLTs) by specialize