Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kamalalayam Raghavan Rajalekshmy"'
Autor:
Natarajan Sudhakar, Nirmala Karunakaran Nancy, Thangarajan Rajkumar, Kamalalayam Raghavan Rajalekshmy
Publikováno v:
Blood research
Background This study characterized clonal IG heavy V-D-J (IGH) gene rearrangements in South Indian patients with precursor B-cell acute lymphoblastic leukemia (precursor B-ALL) and identified age-related predominance in VDJ rearrangements. Methods I
Autor:
S. Uma, Thangarajan Rajkumar, Kamalalayam Raghavan Rajalekshmy, T. Parija, S. Shirley, S. Ayyappan
Publikováno v:
Journal of Biosciences. 30:371-376
The Ewing's sarcoma family can present diagnostic difficulties. In the past the basis of diagnosis has been a exclusion. Identification of a specific translocation especially t(11;22) (EWS-FLI 1 fusion gene), which is seen in nearly 85 percent of Ewi
Autor:
Arcot Radhakrishnan Abitha, Viswanathan Shanta, Kamalalayam Raghavan Rajalekshmy, Radhakrishnan Pramila, Tenali Gnanasagar
Publikováno v:
Leukemia Research. 21:119-124
Immunophenotypic analysis of 285 newly diagnosed previously untreated, unselected, acute lymphoblastic leukaemia cases carried out at the Cancer Institute (W.I.A) in Madras reveals that 126 (44.2%) cases showed T-immunophenotype. The study was conduc
Autor:
Natarajan Sudhakar, Karunakaran Nirmala Nancy, Thangarajan Rajkumar, Kamalalayam Raghavan Rajalekshmy
Publikováno v:
Journal of genetics. 90(2)
Chromosomal translocation is the hallmark of leukaemias and acute lymphoblastic leukaemia (ALL) in particular. DNA damage arises from endogenous and exogenous genotoxic factors and lack of complete fidelity in DNA-repair leads to chromosomal transloc
Autor:
Natarajan, Sudhakar, Nirmala Karunakaran, Nancy, Kamalalayam Raghavan, Rajalekshmy, Thangarajan, Rajkumar
Publikováno v:
Iranian journal of immunology : IJI. 6(3)
Precursor B-Acute Lymphoblastic Leukemia (precursor B-ALL) occurs due to the uncontrolled proliferation of B-lymphoid precursors arrested at a particular stage of B-cell development. Precursor-B-ALL is classified mainly into pro-B-ALL, common-ALL and
Autor:
Kamalalayam Raghavan Rajalekshmy, Thangarajan Rajkumar, Nirmala Karunakaran Nancy, Natarajan Sudhakar, Ganapathi Ramanan
Publikováno v:
American journal of hematology. 82(3)
Clonal T-cell receptor (TCR) gamma and delta gene rearrangements were studied in 40 T-ALL cases (pediatrics, 29; adults, 11) using PCR with homo-heteroduplex analysis. At least one clonal TCRG or TCRD rearrangement was detected in 34 (85%) cases. TCR
Autor:
Kamalalayam Raghavan Rajalekshmy, Radhakrishnan Pramila, Tenali Gnanasagar, Vasudevan Maitreyan, Viswanathan Shanta, Arcot Radhakrishnan Abitha
Publikováno v:
Leukemia research. 18(3)
At the Cancer Institute, Madras, India, we have performed immunophenotyping in 125 untreated cases of acute lymphoblastic leukaemia using a panel of 16 monoclonal antibodies and the avidine-biotin immunoperoxidase technique in a haematology autoanaly