Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Kamala K. Vasu"'
Autor:
A. Abiramasundari, Rahul P. Joshi, Hitesh B. Jalani, Jayesh A. Sharma, Dhaivat H. Pandya, Amit N. Pandya, Vasudevan Sudarsanam, Kamala K. Vasu
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 4, Iss 6, Pp 374-383 (2014)
The stability of the drug actarit was studied under different stress conditions like hydrolysis (acid, alkaline and neutral), oxidation, photolysis and thermal degradation as recommended by International Conference on Harmonization (ICH) guidelines.
Externí odkaz:
https://doaj.org/article/96993f62a6cb48e28fce96931c9f7fa2
Publikováno v:
The Chemistry and Bioactive Components of Turmeric ISBN: 9781788015554
Turmeric (Curcuma longa), from the Zingiberaceae family, is an important herb. Its rhizomes are widely used throughout the world as a principal spice and drug. Turmeric is taken as a therapeutic adjuvant assuming that it is fully safe with different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b8de1d145989346acefb27a3944fa5e
https://doi.org/10.1039/9781788015936-00293
https://doi.org/10.1039/9781788015936-00293
Autor:
Hemantkumar D. Ingawale, Kamala K. Vasu, Dhaivat H. Pandya, Milee Agarwal, Jayesh A. Sharma, Sneha R. Sagar
Publikováno v:
Current Bioactive Compounds. 14:254-263
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5c7fa25b3585a4e5c5ab58955e2b37a
https://doi.org/10.2174/1573407213666170329131557
https://doi.org/10.2174/1573407213666170329131557
Autor:
Sonja Kachler, Jitendra C. Kaila, Amit N. Pandya, Dhaivat H. Pandya, Kamala K. Vasu, Veronica Salmaso, Hitesh B. Jalani, Stefano Moro, Karl-Norbert Klotz, Arshi B. Baraiya
Publikováno v:
MedChemComm. 9:676-684
A small-molecule combinatorial library of 24 compounds with 2-aminoimidazole and 2-aminoimidazolyl-thiazole derivatives was synthesized using a 2-chloro trityl resin. The generated compound library was tested against all the human adenosine receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05714c6d8973bce319adb9d8b82905f0
https://doi.org/10.1039/c7md00643h
https://doi.org/10.1039/c7md00643h
Autor:
Milee Agarwal, Chander Singh Digwal, Amit N. Pandya, Dhaivat H. Pandya, Sneha Patel, Kamala K. Vasu, Jayesh A. Sharma
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:5463-5466
A series of new imidazo[1,2-a]pyridine linked with thiazole/thiophene motif through a keto spacer were synthesized and tested for their cytotoxic potential against three human cancer cell lines including A549, HeLa and U87-MG using MTT assay. Compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bfafdb910eecdaaadc3ee84c7d6a95
https://doi.org/10.1016/j.bmcl.2017.10.060
https://doi.org/10.1016/j.bmcl.2017.10.060
Autor:
Triveni R. Pardhi, Kamala K. Vasu
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 36:177-194
PTEN, a tumor suppressor protein, gets deactivated by casein kinase 2 (CK2) and glycogen synthase kinase 3β (GSK3β), which are the major causes of PI3K/AKT-driven tumors. To surmount this problem, the multi-target inhibitor strategy may be of great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae8bd3e634f37ef536e867146367c1f
https://doi.org/10.1080/07391102.2016.1270856
https://doi.org/10.1080/07391102.2016.1270856
Autor:
Rajesh D. Das, Kamala K. Vasu, Nirupa B. Panchal, Sneha R. Sagar, V. Sudarsanam, Manish Nivsarkar, Devendra Singh
Publikováno v:
Bioorganic & Medicinal Chemistry. 36:116091
Alzheimer's disease (AD) is a neurodegenerative disease majorly affecting old age populations. Various factors that affect the progression of the disease include, amyloid plaque formation, neurofibrillary tangles, inflammation, oxidative stress, etc.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a455f2ce9dc691ab34bb51dcb7425ca
https://doi.org/10.1016/j.bmc.2021.116091
https://doi.org/10.1016/j.bmc.2021.116091
Casein kinase 2 (CK2) and glycogen synthase kinase-3beta (GSK3β) are responsible for the phosphorylation of a tumor suppressor protein (PTEN) in a cooperative manner which causes its deactivation. Thus, it is essential to inhibit both kinases simult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2630ede2f8a6210ccd67d28b34f547eb
https://europepmc.org/articles/PMC6148497/
https://europepmc.org/articles/PMC6148497/
Autor:
Manish Nivsarkar, Sneha R. Sagar, Dhaivat H. Pandya, Nirupa B. Panchal, Devendra Singh, V. Sudarsanam, Rajesh D. Das, Kamala K. Vasu
Publikováno v:
ACS chemical neuroscience. 9(7)
Alzheimer's disease (AD) is associated with multiple neuropathological events including β-site amyloid precursor protein cleaving enzyme-1 (BACE-1) inhibition and neuronal inflammation, ensuing degeneracy, and death to neuronal cells. Targeting such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512f8c8fffc7d104ac12f7d52ab94bdb
https://pubmed.ncbi.nlm.nih.gov/29697965
https://pubmed.ncbi.nlm.nih.gov/29697965
Autor:
Jessica K. Agarwal, Sneha R. Sagar, Kamala K. Vasu, Manish Nivsarkar, Dhaivat H. Pandya, Ranjeet Prasad Dash
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:4428-4433
We report the design, synthesis, biological activity and docking studies of series of novel pyrazolo[3,4-d]pyrimidinones as DPP-IV inhibitors in diabetes. Molecules were synthesized and evaluated for their DPP-IV inhibition activity. Compounds 5e, 5k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67794bfcfa0b4793633bd12bef67cf12
https://doi.org/10.1016/j.bmcl.2015.09.015
https://doi.org/10.1016/j.bmcl.2015.09.015