Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kamal M. Al-Shami"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Angiogenesis is a vital process for the growth and dissemination of solid cancers. Numerous molecular pathways are known to drive angiogenic switch in cancer cells promoting the growth of new blood vessels and increased incidence of distant metastasi
Externí odkaz:
https://doaj.org/article/6711dc9428fc4665a9c6ce82200d3f51
Autor:
Ihab M. Abdallah, Kamal M. Al-Shami, Amer E. Alkhalifa, Nour F. Al-Ghraiybah, Claudia Guillaume, Amal Kaddoumi
Publikováno v:
Molecules, Vol 28, Iss 3, p 1249 (2023)
Alzheimer’s disease (AD) is characterized by several pathological hallmarks, including the deposition of amyloid-β (Aβ) plaques, neurofibrillary tangles, blood–brain barrier (BBB) dysfunction, and neuroinflammation. Growing evidence support the
Externí odkaz:
https://doaj.org/article/32acd4122fb8431eba918d80cb3d5ce1
Publikováno v:
Patient Preference and Adherence. 17:895-903
Kamal M Al-Shami,1,2,* Wesam S Ahmed,3,* Karem H Alzoubi1 1Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan; 2Faculty of Biosciences, University of Heidelberg, Heidelberg,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed665ccb591624464611f5458111b2cd
https://doi.org/10.2147/ppa.s402769
https://doi.org/10.2147/ppa.s402769
Autor:
Carina R. Maier, Oliver Hartmann, Cristian Prieto-Garcia, Kamal M. Al-Shami, Lisa Schlicker, Felix C. E. Vogel, Silke Haid, Kevin Klann, Viktoria Buck, Christian Münch, Werner Schmitz, Elias Einig, Bastian Krenz, Marco A. Calzado, Martin Eilers, Nikita Popov, Mathias T. Rosenfeldt, Markus E. Diefenbacher, Almut Schulze
Publikováno v:
Cell Death & Differentiation.
SREBP2 is a master regulator of the mevalonate pathway (MVP), a biosynthetic process that drives the synthesis of dolichol, heme A, ubiquinone and cholesterol and also provides substrates for protein prenylation. Here, we identify SREBP2 as a novel s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daa7350dfb4e409ead8c22bfc7313fb8
https://doi.org/10.1038/s41418-023-01173-6
https://doi.org/10.1038/s41418-023-01173-6
Autor:
Ihab M. Abdallah, Kamal M. Al-Shami, Euitaek Yang, Junwei Wang, Claudia Guillaume, Amal Kaddoumi
Publikováno v:
ACS chemical neuroscience. 13(7)
Alzheimer's disease (AD) is the most common form of dementia among several neurodegenerative disorders afflicting the elderly. AD is characterized by the deposition of extracellular amyloid-β (Aβ) plaques, disrupted blood-brain barrier (BBB), and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c48b94494981fd68e64cf7b9b71de7
https://pubmed.ncbi.nlm.nih.gov/35263086
https://pubmed.ncbi.nlm.nih.gov/35263086
Publikováno v:
PloS one. 17(6)
Jordan was the first Arab country to enact clinical research regulations. The country has a well-flourished pharmaceutical industry that leans heavily on clinical research (CR) for drug development and post-marketing surveillance. In this cross-secti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b1113dd7fffbde3fc031e90e8e4c64
https://pubmed.ncbi.nlm.nih.gov/35749422
https://pubmed.ncbi.nlm.nih.gov/35749422
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1231, p 1231 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences
Volume 22
Issue 3
In Alzheimer&rsquo
s disease (AD), several studies have reported blood-brain barrier (BBB) breakdown with compromised function. P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) are transport proteins localized at the BBB luminal
s disease (AD), several studies have reported blood-brain barrier (BBB) breakdown with compromised function. P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) are transport proteins localized at the BBB luminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bf7a0c373b206c49bec8b652041d98
https://doi.org/10.3390/ijms22031231
https://doi.org/10.3390/ijms22031231
Publikováno v:
Experimental and Molecular Pathology. 113:104364
Colorectal cancer (CRC) is the third most common carcinoma worldwide. Despite the progress in screening and treatment, CRC remains a leading cause of cancer-related mortality. Alterations to normal nucleic acid processing may drive neoplastic transfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1e7ab7579224eef8603311dbab256f
https://doi.org/10.1016/j.yexmp.2019.104364
https://doi.org/10.1016/j.yexmp.2019.104364
Publikováno v:
OncoTargets and therapy
Nehad M Ayoub, Kamal M Al-Shami, Mohammad A Alqudah, Nizar M Mhaidat Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan Abstract: MET is a receptor tyrosine kinase known for its pleiotropi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f493b05d417e553d18b10865c6139455
https://www.dovepress.com/crizotinib-a-met-inhibitor-inhibits-growth-migration-and-invasion-of-b-peer-reviewed-article-OTT
https://www.dovepress.com/crizotinib-a-met-inhibitor-inhibits-growth-migration-and-invasion-of-b-peer-reviewed-article-OTT
Publikováno v:
Cancer Research. 78:2937-2937
MET is a receptor tyrosine kinase known to be associated with cancer development and progression. Dysregulations of MET expression and/or signaling have been reported in breast cancer patients and determined to be associated with inferior outcomes re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c83d5b0766cde104eb5c5ea25ac2c984
https://doi.org/10.1158/1538-7445.am2018-2937
https://doi.org/10.1158/1538-7445.am2018-2937