Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kamal Kant Kant Sahu"'
Autor:
Kamal Kant Kant Sahu, Yeonjung Jo, Beverly Chigarira, Jong Taek Kim, Nicolas Sayegh, Georges Gebrael, Nishita Tripathi, Shruti Adidam Kumar, Vinay Mathew Thomas, Haoran Li, Roberto Nussenzveig, Manish Kohli, Sumati Gupta, Benjamin L. Maughan, Neeraj Agarwal, Umang Swami
Publikováno v:
Journal of Clinical Oncology. 41:233-233
233 Background: In general, older pts are likely to have an advanced stage PCa, hence poor overall survival (PMID: 18660852). Owing to increased awareness and better diagnostics, the incidence of PCa has steadily increased amongst older adolescents a
Autor:
Jennifer Lloyd, Blake Nordblad, Kamal Kant Kant Sahu, Umang Swami, Tenzin Kunsang Phunrab, Julia Anne Batten, Lindsay Maxwell, Manish Kohli, Sumati Gupta, Benjamin L. Maughan, Neeraj Agarwal
Publikováno v:
Journal of Clinical Oncology. 41:105-105
105 Background: In clinical trials, treatment efficacy rates are based on participants who can tolerate treatment through study endpoints. Attrition from clinical trials can potentially lead to biased results (PMID: 30379822). Many oncology clinical
Autor:
Vinay Mathew Thomas, Beverly Chigarira, Georges Gebrael, Nicolas Sayegh, Nishita Tripathi, Yeonjung Jo, Roberto Nussenzveig, Kamal Kant Kant Sahu, Haoran Li, Clara Tandar, Divyam Goel, Taylor Ryan McFarland, James Brundage, Benjamin L. Maughan, Umang Swami, Neeraj Agarwal
Publikováno v:
Journal of Clinical Oncology. 41:231-231
231 Background: Increased Body Mass Index (BMI) has been linked to increased prostate cancer incidence, recurrence, and mortality (PMID: 35538398). Herein, we sought to investigate the underlying differences in gene expression profiles based on BMI i
Autor:
Haoran Li, Kamal Kant Kant Sahu, Georges Gebrael, Beverly Chigarira, Vinay Mathew Thomas, Yeonjung Jo, Shruti Adidam Kumar, Blake Nordblad, James Brundage, Nishita Tripathi, Nicolas Sayegh, Umang Swami, Neeraj Agarwal, Benjamin L. Maughan
Publikováno v:
Journal of Clinical Oncology. 41:726-726
726 Background: VTE is a common complication in pts with mRCC. Identifying pts with mRCC at the highest risk of developing VTE may provide the rationale for initiating prophylactic anticoagulation. Methods: In this IRB-approved retrospective study, p
Autor:
Vinay Mathew Thomas, Nicolas Sayegh, Beverly Chigarira, Georges Gebrael, Yeonjung Jo, Nishita Tripathi, Roberto Nussenzveig, Haoran Li, Kamal Kant Kant Sahu, Clara Tandar, Divyam Goel, Puja Iyer, Benjamin L. Maughan, Umang Swami, Neeraj Agarwal
Publikováno v:
Journal of Clinical Oncology. 41:234-234
234 Background: Pts with mCSPC receiving i-ADT and achieving a PSA nadir ≤0.2 ng/mL (PSA-L) demonstrate significantly better overall survival (OS) as compared to those with a PSA nadir > 0.2 ng/mL (PSA-H) (Chi AUA 2021, Saad ASCO 2022). We hypothes
Autor:
Kamal Kant Kant Sahu, Haoran Li, Vinay Mathew Thomas, Mallory Benson, Josiah Hawaks, Julian Brown, Kelli Thorne, Kathy Sherwin, Jackson Cheney, Kenneth M. Boucher, Sumati Gupta, Manish Kohli, Umang Swami, Neeraj Agarwal, Benjamin L. Maughan
Publikováno v:
Journal of Clinical Oncology. 41:364-364
364 Background: Prostate cancer (PCa) patients (pts) with DNA repair defects (aka “BRCAness”) generally have more aggressive disease and a worse overall prognosis compared to men without BRCAness (PMID: 33781305). Biochemical recurrence (BCR) dev
Autor:
Nishita Tripathi, Haoran Li, Beverly Chigarira, Shruti Adidam Kumar, Kim JongTaek, Nicolas Sayegh, Georges Gebrael, Yeonjung Jo, Kamal Kant Kant Sahu, Vinay Mathew Thomas, Roberto Nussenzveig, Divyam Goel, Clara Tandar, Nityam Rathi, Umang Swami, Neeraj Agarwal, Benjamin L. Maughan
Publikováno v:
Journal of Clinical Oncology. 41:244-244
244 Background: Pre-existing DM is associated with increased PCa specific and all-cause mortality in men with prostate cancer (PMID: 27652121). However, the underlying reasons are unclear. We hypothesized that transcriptomic profile of metastatic PCa
Autor:
Tori Seasor, Michael Balatico, Beverly Chigarira, Kamal Kant Kant Sahu, Jong Taek Kim, Anna P Matynia, Marc Barry, Daniel Joseph Albertson, Jon Mahlow, Umang Swami, Neeraj Agarwal, Deepika Sirohi
Publikováno v:
Journal of Clinical Oncology. 41:259-259
259 Background: Histological subtypes of Pca are generally associated with worse clinical outcomes. Here in, we hypothesize that histological subtypes of PCa, e.g., cribriform, and signet ring-like, may have distinct genomic characteristics that may
Autor:
Kamal Kant Kant Sahu, Nishita Tripathi, Beverly Chigarira, Nicolas Sayegh, Vinay Mathew Thomas, Haoran Li, Yeonjung Jo, Georges Gebrael, Puja Iyer, Roberto Nussenzveig, Neeraj Agarwal, Benjamin L. Maughan, Sumati Gupta, Umang Swami
Publikováno v:
Journal of Clinical Oncology. 41:561-561
561 Background: Understanding the influences of cigarette smoke exposure at the gene expression level may have clinical significance and therapeutic implications. Investigating variations in the gene expression patterns could provide insights into di
Autor:
Umang Swami, Caitlin Faust, Samuel Leonhart, Benjamin Haaland, Kristen Jones, Haoran Li, Kamal Kant Kant Sahu, Vinay Mathew Thomas, Tenzin Kunsang Phunrab, Julia Batten, Lindsay Maxwell, Jennifer Lloyd, Manish Kohli, Sumati Gupta, Kelli Thorne, Benjamin L. Maughan, Neeraj Agarwal
Publikováno v:
Journal of Clinical Oncology. 41:TPS294-TPS294
TPS294 Background: EV, an antibody-drug conjugate (ADC), consists of a fully human antibody directed against the extracellular domain of Nectin-4 (N4), which is conjugated to a microtubule-disrupting agent, monomethyl auristatin E (MMAE), by a protea