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pro vyhledávání: '"Kamal G. Shah"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The simplest point-of-care assays are usually paper and plastic devices that detect proteins or nucleic acids at low cost and minimal user steps, albeit with poor limits of detection. Digital assays improve limits of detection and analyte qu
Externí odkaz:
https://doaj.org/article/86e407578da248b6b215f73fe52c0d93
Autor:
Kamal G. Shah, Mike Roller, Sujatha Kumar, Steven Bennett, Erin Heiniger, Katriel Looney, Joshua Buser, Joshua D. Bishop, Paul Yager
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Recent advances in electronics and microfluidics have enabled several research groups to develop fully integrated, sample-to-result isothermal nucleic acid amplification test (NAAT) platforms for the point of care. However, high component counts and
Externí odkaz:
https://doaj.org/article/cfb0273103444ab6a28f45f387d4e9a5
Autor:
Ian T. Hull, Enos C. Kline, Gaurav K. Gulati, Jack Henry Kotnik, Nuttada Panpradist, Kamal G. Shah, Qin Wang, Lisa Frenkel, James Lai, Joanne Stekler, Barry R. Lutz
Publikováno v:
Anal Chem
Point-of-care diagnostics often use isothermal nucleic acid amplification for qualitative detection of pathogens in low-resource healthcare settings, but lack sufficient precision for quantitative applications such as HIV viral load monitoring. Altho
Autor:
Kamal G Shah, Dylan Guelig, Steven Diesburg, Joshua Buser, Robert Burton, Paul LaBarre, Rebecca Richards-Kortum, Bernhard Weigl
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139449 (2015)
Previous chemical heater designs for isothermal nucleic acid amplification have been based on solid-liquid phase transition, but using this approach, developers have identified design challenges en route to developing a low-cost, disposable device. H
Externí odkaz:
https://doaj.org/article/781819bcef80477daef5a376add66b43
Publikováno v:
Methods in enzymology. 589
The design of appropriate diagnostic assays for the point of care requires development of suitable biosensors, detection methods, and diagnostic platforms for sensitive, quantitative detection of biological analytes. Protein targets in particular are