Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kamal Albarazanji"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Meal ingestion elicits a variety of neuronal, physiological and hormonal responses that differ in healthy, obese or diabetic individuals. The mixed meal tolerance test (MMTT) is a well-established method to evaluate pancreatic β-cell reserv
Externí odkaz:
https://doaj.org/article/c7194540df2a40858f81ef72ab541830
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Meal ingestion elicits a variety of neuronal, physiological and hormonal responses that differ in healthy, obese or diabetic individuals. The mixed meal tolerance test (MMTT) is a well-established method to evaluate pancreatic β-cell reserve and glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fee7208f4019cd0a8235b25bd02e3a
https://doaj.org/article/c7194540df2a40858f81ef72ab541830
https://doaj.org/article/c7194540df2a40858f81ef72ab541830
Autor:
Xuqing Zhang, James Lenhard, Richard Alexander, Weimei Sun, Maxwell D. Cummings, Bin Zhu, Kamal Albarazanji, Mina Wang, James C. Lanter, Jiejun Wu, James N. Leonard, Yue-Mei Zhang
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 375:510-521
Inhibition of the serine protease enteropeptidase (EP) opens a new avenue to the discovery of chemotherapeutics for the treatment of metabolic diseases. Camostat has been used clinically for treating chronic pancreatitis in Japan; however, the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a701c9c6c9e4ab493881188b5765359
https://doi.org/10.1124/jpet.120.000219
https://doi.org/10.1124/jpet.120.000219
Autor:
James N. Leonard, Weimei Sun, Mina Wang, Kamal Albarazanji, James Lenhard, James C. Lanter, Mark J. Macielag, Maxwell D. Cummings, Xuqing Zhang, Bin Zhu, Brahma Ghosh
Publikováno v:
Bioorganicmedicinal chemistry letters. 40
A novel series of guanidinebenzoate enteropeptidase and trypsin dual inhibitors has been discovered and SAR studies were conducted. Optimization was focused on improving properties for gut restriction, including increased aqueous solubility, lower ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9008f50fd7165b9bd4c40cc0d890923
https://pubmed.ncbi.nlm.nih.gov/33713780
https://pubmed.ncbi.nlm.nih.gov/33713780
Autor:
James Lenhard, Wensheng Lang, Pamela J. Hornby, Cassandre R. Cavanaugh, Kamal Albarazanji, Bhanu Singh, James C. Lanter, Matthew Jennis
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Trypsin is the major serine protease responsible for intestinal protein digestion. An inhibitor, camostat (CS), reduced weight gain, hyperglycemia, and dyslipidemia in obese rats; however, the mechanisms for these are largely unknown. We reasoned tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d32cbe90120cf248811b267bd0e6a7b
https://pubmed.ncbi.nlm.nih.gov/30920846
https://pubmed.ncbi.nlm.nih.gov/30920846
Autor:
Cassandre R. Cavanaugh, Matthew Jennis, James Lenhard, James C. Lanter, Kamal Albarazanji, Pamela J. Hornby, Shobha Seetharam
Publikováno v:
Gastroenterology. 154:S-218
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6099cac0b5cab19d3836fe9e99b8e5f
https://doi.org/10.1016/s0016-5085(18)31119-3
https://doi.org/10.1016/s0016-5085(18)31119-3