Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kamakshi P Devalraju"'
Autor:
Deepak Tripathi, Elwyn Welch, Satyanarayana Swamy Cheekatla, Rajesh Kumar Radhakrishnan, Sambasivan Venkatasubramanian, Padmaja Paidipally, Abhinav Van, Buka Samten, Kamakshi P Devalraju, Venkata Sanjeev Kumar Neela, Vijaya Lakshmi Valluri, Carol Mason, Steve Nelson, Ramakrishna Vankayalapati
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007174 (2018)
In the current study, we used a mouse model and human blood samples to determine the effects of chronic alcohol consumption on immune responses during Mycobacterium tuberculosis (Mtb) infection. Alcohol increased the mortality of young mice but not o
Externí odkaz:
https://doaj.org/article/a165f4be7a73421798514df756d6ec4f
Autor:
Deepak Tripathi, Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Tanmoy Mukherjee, Padmaja Paidipally, Rajesh Kumar Radhakrishnan, Igor Dozmorov, Abhinav Vankayalapati, Mohammad Soheb Ansari, Varalakshmi Mallidi, Anvesh Kumar Bogam, Karan P. Singh, Buka Samten, Vijaya Lakshmi Valluri, Ramakrishna Vankayalapati
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
To determine the mechanisms that mediate resistance to Mycobacterium tuberculosis (M. tuberculosis) infection in household contacts (HHCs) of patients with tuberculosis (TB), we followed 452 latent TB infection–negative (LTBI–) HHCs for 2 years.
Externí odkaz:
https://doaj.org/article/dfdfd08ec87441319bfc8a3e0a6fb791
Autor:
Kamakshi Prudhula Devalraju, Deepak Tripathi, Venkata Sanjeev Kumar Neela, Padmaja Paidipally, Rajesh Kumar Radhakrishnan, Karan P. Singh, Mohammad Soheb Ansari, Martin Jaeger, Romana T. Netea-Maier, Mihai G. Netea, Sunmi Park, Sheue-yann Cheng, Vijaya Lakshmi Valluri, Ramakrishna Vankayalapati
Publikováno v:
JCI Insight, Vol 6, Iss 13 (2021)
In the current study, we followed 839 household contacts (HHCs) of tuberculosis (TB) patients for 2 years and identified the factors that enhanced the development of TB. Fourteen of the 17 HHCs who progressed to TB were in the 15- to 30-year-old age
Externí odkaz:
https://doaj.org/article/3d702333e28b4a3ca020d609b6281e30
Autor:
Deepak Tripathi, Rajesh Kumar Radhakrishnan, Ramya Sivangala Thandi, Padmaja Paidipally, Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Madeline Kay McAllister, Buka Samten, Vijaya Lakshmi Valluri, Ramakrishna Vankayalapati
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009578 (2021)
[This corrects the article DOI: 10.1371/journal.ppat.1008140.].
Externí odkaz:
https://doaj.org/article/5bfe595fc3af4efcaa9740bad18880da
Autor:
Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Siva Sai Krovvidi, Ramakrishna Vankayalapati, Vijaya Lakshmi Valluri
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257185 (2021)
PurposeTuberculosis (TB) is the leading cause of infectious disease related mortality, and only 10% of the infected individuals develop active disease. The likelihood of progression of latent tuberculosis infection (LTBI) to active TB disease is high
Externí odkaz:
https://doaj.org/article/d4f5d40d28274cb9a9e2d9cf2e3a48b5
Autor:
Deepak Tripathi, Rajesh Kumar Radhakrishnan, Ramya Sivangala Thandi, Padmaja Paidipally, Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Madeline Kay McAllister, Buka Samten, Vijaya Lakshmi Valluri, Ramakrishna Vankayalapati
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008140 (2019)
Previously, we found that pathological immune responses enhance the mortality rate of Mycobacterium tuberculosis (Mtb)-infected mice with type 2 diabetes mellitus (T2DM). In the current study, we evaluated the role of the cytokine IL-22 (known to pla
Externí odkaz:
https://doaj.org/article/f93ba82150a045c2beb975e533bc75d2
Autor:
Philip Raj Abraham, Kamakshi Prudhula Devalraju, Vishwanath Jha, Vijaya Lakshmi Valluri, Sangita Mukhopadhyay
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207787 (2018)
Latent tuberculosis infection (LTBI) is a clinically distinct category of Mycobacterium tuberculosis (Mtb) infection that needs to be diagnosed at the initial stage. We have reported earlier that one of the Mtb proline-proline-glutamic acid (PPE) pro
Externí odkaz:
https://doaj.org/article/57bfa9dd549d4654962cb00c436f4fbd
Autor:
Deepak Tripathi, Elwyn Welch, Satyanarayana Swamy Cheekatla, Rajesh Kumar Radhakrishnan, Sambasivan Venkatasubramanian, Padmaja Paidipally, Abhinav Van, Amy R. Tvinnereim, Buka Samten, Kamakshi P. Devalraju, Venkata Sanjeev Kumar Neela, Vijaya Lakshmi Valluri, Carol Mason, Steve Nelson, Ramakrishna Vankayalapati
Publikováno v:
The Journal of Immunology. 200:114.14-114.14
In the current study, we determined the effects of chronic alcohol consumption on the mortality of young and old mice and immune responses during Mycobacterium tuberculosis (Mtb) infection. Eighty percent of Mtb H37Rv infected alcohol-fed young mice
Autor:
Anuradha, Bandaru, Kamakshi P, Devalraju, Padmaja, Paidipally, Rohan, Dhiman, Sambasivan, Venkatasubramanian, Peter F, Barnes, Ramakrishna, Vankayalapati, Vijayalakshmi, Valluri
Publikováno v:
European journal of immunology. 44(7)
We studied the factors that regulate IL-23 receptor expression and IL-17 production in human tuberculosis infection. Mycobacterium tuberculosis (M. tb)-stimulated CD4(+) T cells from tuberculosis patients secreted less IL-17 than did CD4(+) T cells f
Autor:
Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Sharadambal Sunder Ramaseri, Arunabala Chaudhury, Abhinav Van, Siva Sai Krovvidi, Ramakrishna Vankayalapati, Vijaya Lakshmi Valluri
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background IL-17 and IL-22 cytokines play an important role in protective immune responses against Mycobacterium tuberculosis (Mtb) infection. Information on the production of these cytokines and the factors that regulate their production in
Externí odkaz:
https://doaj.org/article/d7a757c4a01941bdbb3f3265743173ab