Zobrazeno 1 - 10
of 603
pro vyhledávání: '"Kam W Leong"'
Publikováno v:
Journal of Tissue Engineering, Vol 12 (2021)
The COVID-19 pandemic has aggravated a preexisting epidemic: the opioid crisis. Much literature has shown that the circumstances imposed by COVID-19, such as social distancing regulations, medical and financial instability, and increased mental healt
Externí odkaz:
https://doaj.org/article/c1fd96722c6640abb47438a140e3f7e2
Publikováno v:
Journal of Tissue Engineering, Vol 11 (2020)
To reduce excessive scarring in wound healing, electrospun nanofibrous meshes, composed of haloarchaea-produced biodegradable elastomer poly(3-hydroxybutyrate- co -3-hydroxyvalerate) (PHBV), are fabricated for use as a wound dressing. Three PHBV poly
Externí odkaz:
https://doaj.org/article/bd27e6bf7564416a989bd0bf85e6efa3
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 2, Pp n/a-n/a (2016)
Abstract Engineered bacteria have great potential for medical and environmental applications. Fulfilling this potential requires controllability over engineered behaviors and scalability of the engineered systems. Here, we present a platform technolo
Externí odkaz:
https://doaj.org/article/94dcb7f194d245b88b9d8fccb639192d
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114698 (2014)
Mesenchymal stem/stromal cells respond to physical cues present in their microenvironment such as substrate elasticity, geometry, or topography with respect to morphology, proliferation, and differentiation. Although studies have demonstrated the rol
Externí odkaz:
https://doaj.org/article/d62175a867bf481f9dff6848d22c7221
Autor:
Hye Sung Kim, Yang Xiao, Xuejing Chen, Siyu He, Jongwon Im, Moshe J. Willner, Michael O. Finlayson, Cong Xu, Huixiang Zhu, Se Joon Choi, Eugene V. Mosharov, Hae‐Won Kim, Bin Xu, Kam W. Leong
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Understanding the impact of long‐term opioid exposure on the embryonic brain is critical due to the surging number of pregnant mothers with opioid dependency. However, this has been limited by human brain inaccessibility and cross‐specie
Externí odkaz:
https://doaj.org/article/b46900ca4b6748a09f94984845285e8f
Autor:
Elena Alexander, Kam W. Leong
Publikováno v:
Frontiers in Nanotechnology, Vol 6 (2024)
The application of laser-synthesized nanodiamonds (LNDs) is of great interest to biomedical researchers and drug developers because this emerging method of synthesis yields nanodiamonds of consistent size (
Externí odkaz:
https://doaj.org/article/6433295fe98644f4bb5d4455ad392a33
Autor:
Nicolas Christoforou, Brian Liau, Syandan Chakraborty, Malathi Chellapan, Nenad Bursac, Kam W Leong
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65963 (2013)
The mammalian heart has little capacity to regenerate, and following injury the myocardium is replaced by non-contractile scar tissue. Consequently, increased wall stress and workload on the remaining myocardium leads to chamber dilation, dysfunction
Externí odkaz:
https://doaj.org/article/704e201be9124dbfb98e823f9e59501e
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75548 (2013)
A large percentage of the population may be expected to experience painful symptoms or disability associated with intervertebral disc (IVD) degeneration - a condition characterized by diminished integrity of tissue components. Great interest exists i
Externí odkaz:
https://doaj.org/article/fe406fb71a8a42dabc8ca9afebf7c97b
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64342 (2013)
Viral vectors remain the most efficient and popular in deriving induced pluripotent stem cells (iPSCs). For translation, it is important to silence or remove the reprogramming factors after induction of pluripotency. In this study, we design an excis
Externí odkaz:
https://doaj.org/article/fa6a782ca870493b81d10b48967a0b15
Autor:
Nicolas Christoforou, Malathi Chellappan, Andrew F Adler, Robert D Kirkton, Tianyi Wu, Russell C Addis, Nenad Bursac, Kam W Leong
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63577 (2013)
Transient overexpression of defined combinations of master regulator genes can effectively induce cellular reprogramming: the acquisition of an alternative predicted phenotype from a differentiated cell lineage. This can be of particular importance i
Externí odkaz:
https://doaj.org/article/36961434f43a4058af0d11d6d51700d2