Oxyphylla A exerts antiparkinsonian effects by ameliorating 6-OHDA-induced mitochondrial dysfunction and dyskinesia in vitro and in vivo.

Autor: Shao M; School of Bioengineering, Zhuhai Campus of Zunyi Medical University, Zhuhai, China., Zhao C; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macau, China., Pan Z; School of Bioengineering, Zhuhai Campus of Zunyi Medical University, Zhuhai, China., Yang X; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macau, China; Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China., Gao C; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macau, China., Kam GH; Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China., Zhou H; School of Bioengineering, Zhuhai Campus of Zunyi Medical University, Zhuhai, China. Electronic address: zhf@zmu.edu.cn., Lee SM; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macau, China; Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China; Research Centre for Chinese Medicine Innovation, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China; State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China; Research Institute for Smart Ageing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China; Research Institute for Future Food, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China; PolyU-BGI Joint Research Centre for Genomics and Synthetic Biology in Global Deep Ocean Resource, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China. Electronic address: simon-my.lee@polyu.edu.hk.

Publikováno v: Chemico-biological interactions [Chem Biol Interact] 2024 Nov 01; Vol. 403, pp. 111224. Date of Electronic Publication: 2024 Sep 03.