Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kalynn Van Voorhies"'
Autor:
Graydon B. Gereau, Diana Zhou, Kalynn Van Voorhies, Ryan E. Tyler, Jeffrey Campbell, Jackson G. Murray, Ali Alvarez-Pamir, Luke A. Wykoff, Michel A. Companion, Michael R. Jackson, Steven H. Olson, Lawrence S. Barak, Lauren M. Slosky, Ryan P. Vetreno, Joyce Besheer, Zoe A. McElligott
Publikováno v:
Addiction Neuroscience, Vol 13, Iss , Pp 100185- (2024)
Alcohol use disorders (AUDs) impose an enormous societal and financial burden, and world-wide, alcohol misuse is the 7th leading cause of premature death [1]. Despite this, there are currently only 3 FDA approved pharmacological approaches for the tr
Externí odkaz:
https://doaj.org/article/d94961354bbf425ea2efeab23e05c46e
Autor:
Laura C. Ornelas, Giorgia Boero, Kalynn Van Voorhies, Todd K. O'Buckley, Joyce Besheer, A. Leslie Morrow
Publikováno v:
Alcohol: Clinical and Experimental Research. 47:459-469
Each year, more than 140,000 deaths occur due to excessive alcohol use. Alcohol affects multiple circuits in the brain, mainly disrupting the delicate balance between inhibitory γ-aminobutyric acid (GABA) transmission and excitatory glutamate signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af3bf68ae2068729235ec17ab840fb9
https://doi.org/10.1111/acer.15008
https://doi.org/10.1111/acer.15008
Autor:
Elaine A. Gay, Dongliang Guan, Kalynn Van Voorhies, Vineetha Vasukuttan, Kelly M. Mathews, Joyce Besheer, Chunyang Jin
Publikováno v:
J Med Chem
The neuropeptide relaxin-3/RXFP3 system is involved in many important physiological processes such as stress responses, appetite control, and motivation for reward. To date, pharmacological studies of RXFP3 have been limited to peptide ligands. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34bc46e1e337845db6f9a86d0b113122
https://europepmc.org/articles/PMC9255433/
https://europepmc.org/articles/PMC9255433/
Autor:
Dennis F. Lovelock, Wen Liu, Sarah E. Langston, Jiaqi Liu, Kalynn Van Voorhies, Kaitlin A. Giffin, Ryan P. Vetreno, Fulton T. Crews, Joyce Besheer
Publikováno v:
Addiction biology. 27(3)
There is growing evidence that immune signalling may be involved in both the causes and consequences of alcohol abuse. Toll-like receptor (TLR) expression is increased by alcohol consumption and is implicated in AUD, and specifically TLR7 may play an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba56da03c8371be5cf33cb20a57d213
https://pubmed.ncbi.nlm.nih.gov/35470561
https://pubmed.ncbi.nlm.nih.gov/35470561
Autor:
Ryan E. Tyler, Maya N. Bluitt, Kalynn Van Voorhies, Laura C. Ornelas, Benjamin Z.S. Weinberg, Joyce Besheer
Post-traumatic stress disorder (PTSD) confers enhanced vulnerability to develop comorbid alcohol use disorder (AUD). Exposure to the scent of a predator, such as the fox odor TMT, has been used to model a traumatic stressor with relevance to PTSD sym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc6e914979ea4aac42b93b7edf2e66c
https://doi.org/10.1101/2022.02.16.480725
https://doi.org/10.1101/2022.02.16.480725
Autor:
Dennis F. Lovelock, Patrick A. Randall, Kalynn Van Voorhies, Ryan P. Vetreno, Fulton T. Crews, J. Besheer
Publikováno v:
Pharmacol Biochem Behav
Toll-like receptor (TLR) signaling may play an important role in the neuroimmune system’s involvement in the development and maintenance of alcohol use disorder. In the present study we administered TLR3 agonist poly(I:C) in male and female Long-Ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd66b968c0593cb597430cb214fbbb2
https://doi.org/10.1101/2021.10.26.465779
https://doi.org/10.1101/2021.10.26.465779
Autor:
Dennis F. Lovelock, Wen Liu, Sarah E. Langston, Jiaqi Liu, Kalynn Van Voorhies, Kaitlin A. Giffin, Ryan P. Vetreno, Fulton T. Crews, Joyce Besheer
BackgroundThere is growing evidence that immune signaling may be involved in both the causes and consequences of alcohol abuse. Toll-like receptor (TLR) expression is increased by alcohol consumption and is implicated in AUD, and specifically TLR7 ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1acc7150d35ba8b2f5d9fddc8c4ff5c0
https://doi.org/10.1101/2021.10.25.465772
https://doi.org/10.1101/2021.10.25.465772
RTICBM-74 is a Brain-Penetrant CB1 Receptor Allosteric Modulator that Reduces Alcohol Intake in Rats
The endocannabinoid system is implicated in the neuronal mechanisms of alcohol use disorder (AUD), with the cannabinoid receptor subtype 1 (CB1) representing a promising target for AUD therapeutic interventions. We have previously shown negative allo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d64110f5dce5bc62e9a9a7df629a5c6
https://doi.org/10.1101/2021.09.13.460113
https://doi.org/10.1101/2021.09.13.460113
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 380(3)
The endocannabinoid system is implicated in the neuronal mechanisms of alcohol use disorder (AUD), with the cannabinoid receptor subtype 1 (CB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b173fcb6c7901b1e0e8d4c380513f97a
https://pubmed.ncbi.nlm.nih.gov/34930820
https://pubmed.ncbi.nlm.nih.gov/34930820
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Experiencing intrusive distressing memories of a traumatic event(s) is a prominent symptom profile for post-traumatic stress disorder (PTSD). Understanding the neurobiological mechanisms associated with this symptom profile can be invaluab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa9ecf6a38ca5d32258dfbef01769a5
https://pubmed.ncbi.nlm.nih.gov/34390359
https://pubmed.ncbi.nlm.nih.gov/34390359