Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kalyan Pande"'
Autor:
Scott A. Hollingsworth, Cameron L. Noland, Karin Vroom, Anasuya Saha, Miranda Sam, Qinshan Gao, Haihong Zhou, David U. Grandy, Sujata Singh, Zhiyun Wen, Christopher Warren, Xiaohong Shirley Ma, Daniel Malashock, Jennifer Galli, Gwenny Go, Michael Eddins, Todd Mayhood, Karthik Sathiyamoorthy, Arthur Fridman, Fahimeh Raoufi, Yacob Gomez-Llorente, Andrea Patridge, Yinyan Tang, Shi-Juan Chen, Marc Bailly, Chengjie Ji, Laura J. Kingsley, Alan C. Cheng, Bernhard H. Geierstanger, Daniel M. Gorman, Lan Zhang, Kalyan Pande
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Coronaviruses have been the causative agent of three epidemics and pandemics in the past two decades, including the ongoing COVID-19 pandemic. A broadly-neutralizing coronavirus therapeutic is desirable not only to prevent and treat COVID-19
Externí odkaz:
https://doaj.org/article/a9d7ab42a9cb4a6cb05bac47eef92301
Autor:
Kalyan Pande, Scott A. Hollingsworth, Miranda Sam, Qinshan Gao, Sujata Singh, Anasuya Saha, Karin Vroom, Xiaohong Shirley Ma, Tres Brazell, Dan Gorman, Shi-Juan Chen, Fahimeh Raoufi, Marc Bailly, David Grandy, Karthik Sathiyamoorthy, Lan Zhang, Rob Thompson, Alan C. Cheng, Laurence Fayadat-Dilman, Bernhard H. Geierstanger, Laura J. Kingsley
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The SARS-CoV-2 pandemic and particularly the emerging variants have deepened the need for widely available therapeutic options. We have demonstrated that hexamer-enhancing mutations in the Fc region of anti-SARS-CoV IgG antibodies lead to a noticeabl
Externí odkaz:
https://doaj.org/article/145d782d89b84e8a8997fe9cccda8169
Publikováno v:
Journal of Minimal Access Surgery, Vol 19, Iss 4, Pp 466-472 (2023)
Background: Minimally invasive surgery in rectal cancer has gained prominence owing to its various advantages in surgical outcomes. Due to rapid adoption of robotics in rectal surgery, we intended to assess the pace in which surgeons gain proficiency
Externí odkaz:
https://doaj.org/article/922e11ef79614971a527bd6a101cc80a
Publikováno v:
Journal of Minimal Access Surgery, Vol 19, Iss 3, Pp 384-389 (2023)
Background: The application of robotic staplers in surgeries has increased in recent years. Robotic platform enhances ability of the surgeon to directly control and manoeuvre staplers to achieve required angulation and sealing within the confines of
Externí odkaz:
https://doaj.org/article/14fdef163ae74549b37d79780295ce12
Publikováno v:
Nature genetics
Among ~5,000,000 fungal species,1 Candida albicans is exceptional in its lifelong association with humans, either within the gastrointestinal microbiome or as an invasive pathogen.2 Opportunistic infections are generally ascribed to defective host im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10179a5724bb1b6febce7db904a24da
http://europepmc.org/articles/PMC3758371
http://europepmc.org/articles/PMC3758371
Autor:
Drake LaFace, Nico van Rooijen, Elena Brin, James E. Talmadge, Matthew J. Delano, Todd Machemer, Van Tsai, Manjiri Sathe, Terrill K. McClanahan, Kalyan Pande, Lyle L. Moldawer, Joseph H. Phillips, Roanna Ueda
Publikováno v:
Molecular Therapy, 17(3), 508-515. Nature Publishing Group
Pande, K, Ueda, R, Machemer, T, Sathe, M, Tsai, V, Brin, E, Delano, M J, van Rooijen, N, McClanahan, T K, Talmadge, J E, Moldawer, L L, Phillips, J R & Laface, D M 2009, ' Cancer-induced Expansion and Activation of CD11b(+)Gr-1(+) Cells Predispose Mice to Adenoviral-triggered Anaphylactoid-type Reactions ', Molecular Therapy, vol. 17, no. 3, pp. 508-515 . https://doi.org/10.1038/mt.2008.280
Pande, K, Ueda, R, Machemer, T, Sathe, M, Tsai, V, Brin, E, Delano, M J, van Rooijen, N, McClanahan, T K, Talmadge, J E, Moldawer, L L, Phillips, J R & Laface, D M 2009, ' Cancer-induced Expansion and Activation of CD11b(+)Gr-1(+) Cells Predispose Mice to Adenoviral-triggered Anaphylactoid-type Reactions ', Molecular Therapy, vol. 17, no. 3, pp. 508-515 . https://doi.org/10.1038/mt.2008.280
Intravascular delivery (1.5 x 10(9) particles and higher) of recombinant adenovirus (rAd) induces myeloid cell mediated, self-limiting hemodynamic responses in normal mice. However, we observed anaphylactoid-type reactions and exacerbated hemodynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b5cbc77495bbf68c49787c05462abb
https://doi.org/10.1038/mt.2008.280
https://doi.org/10.1038/mt.2008.280
Autor:
Philip O. Scumpia, Lyle L. Moldawer, Robert D. Winfield, Matthew J. Delano, Kalyan Pande, Drake LaFace
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 32:651-655
Cachexia accompanies many chronic inflammatory diseases, including cancer. Lean tissue wasting is only one component of the cancer cachexia response, which also includes anemia, anorexia, a hepatic acute phase protein response, and increased suscepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324327fc3c56d23b0afe3c09c36cb71d
https://doi.org/10.1177/0148607108325075
https://doi.org/10.1177/0148607108325075
Publikováno v:
Proceedings of the National Academy of Sciences. 102:17858-17863
The aryl hydrocarbon receptor (AHR) plays a role in three areas of biology that include the adaptive metabolism of xenobiotics, the toxic responses associated with exposure to 2,3,7,8-tetrachlorodibenzo- p -dioxin (dioxin), and vascular remodeling of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6824b307f9ef32212a28fcf150103a4d
https://doi.org/10.1073/pnas.0504757102
https://doi.org/10.1073/pnas.0504757102
Autor:
Gina M. Zastrow, Kalyan Pande, Stevan B. Jovanovich, Sharron G. Penn, Russell S. Thomas, Mark H. Lewis, Tianhua Hu, Christopher A. Bradfield, David R. Rank, Kevin R. Hayes
Publikováno v:
Environmental Health Perspectives
Traditional models of toxicity have relied on dissecting chemical action into pharmacokinetic and pharmacodynamic processes. However, the integration of genomic information with toxicology will enhance our basic understanding of these processes and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635be343845f4df57d414a107e4e32cc
https://doi.org/10.1289/ehp.02110s6919
https://doi.org/10.1289/ehp.02110s6919
Publikováno v:
Cancer Immunology Research. 5:B49-B49
In order to model pharmacokinetics and pharmacodynamics of pegylated IFNalpha, we utilized hydrodynamic delivery technology using minicircle DNA vectors encoding universal IFNalpha as a rapid and cost-effective method to obtain sustained levels of se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d35d30f67c51d07ba9f24652cc865961
https://doi.org/10.1158/2326-6074.tumimm16-b49
https://doi.org/10.1158/2326-6074.tumimm16-b49