Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kaly A Mueller"'
Autor:
Tiziana Petrozziello, Amanda M Dios, Kaly A Mueller, Christine A Vaine, William T Hendriks, Kelly E Glajch, Alexandra N Mills, Kotchaphorn Mangkalaphiban, Ellen B Penney, Naoto Ito, Cara Fernandez-Cerado, Gierold Paul A Legarda, M Salvie Velasco-Andrada, Patrick J Acuña, Mark A Ang, Edwin L Muñoz, Cid Czarina E Diesta, Regina Macalintal-Canlas, Geraldine Acuña, Nutan Sharma, Laurie J Ozelius, D Cristopher Bragg, Ghazaleh Sadri-Vakili
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243655 (2020)
X-linked Dystonia-Parkinsonism (XDP) is a neurodegenerative disease linked to an insertion of a SINE-VNTR-Alu (SVA)-type retrotransposon within an intron of TAF1. This SVA insertion induces aberrant TAF1 splicing and partial intron retention, thereby
Externí odkaz:
https://doaj.org/article/589a61b80bba4eb7bc6d53099ba584bd
Autor:
Kelly E Glajch, Laura Ferraiuolo, Kaly A Mueller, Matthew J Stopford, Varsha Prabhkar, Achille Gravanis, Pamela J Shaw, Ghazaleh Sadri-Vakili
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164103 (2016)
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease caused by loss of motor neurons. ALS patients experience rapid deterioration in muscle function with an average lifespan of 3-5 years after diagnosis. Currently, the most effective th
Externí odkaz:
https://doaj.org/article/ba52bc4531a84a88a18f6278fedb2d1b
Autor:
James D. Berry, Kaly A. Mueller, Kelly E. Glajch, Alexandra N. Mills, Sheena Chew, Sali M.K. Farhan, Eric J. Granucci, Ghazaleh Sadri-Vakili, Tiziana Petrozziello, James Chan
Publikováno v:
Muscle & Nerve. 62:272-283
Background The exact mechanisms underlying neuroinflammation and how they contribute to amyotrophic lateral sclerosis (ALS) pathogenesis remain unclear. One possibility is the secretion of neurotoxic factors, such as lipocalin-2 (LCN2), that lead to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d6f39b6d15f38bc956da447278e0c2
https://doi.org/10.1002/mus.26911
https://doi.org/10.1002/mus.26911
Autor:
Eric J. Granucci, David R. Elmaleh, Merit Cudkowicz, Alexandra N. Mills, James D. Berry, Ghazaleh Sadri-Vakili, Danielle McGinty, Sabrina Paganoni, Hoang Le, Ana Griciuc, Amanda M. Dios, Rudolph E. Tanzi, João D. Pereira, Kaly A. Mueller
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Accumulating evidence suggests that neuroinflammatory processes are implicated in the initiation and progression of amyotrophic lateral sclerosis (ALS). Previous reports have demonstrated an increase in microgliosis and astrogliosis in the lumbar spi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32853a341c26a4ce7a12df14a49b3b95
http://link.springer.com/article/10.1038/s41598-019-53982-w
http://link.springer.com/article/10.1038/s41598-019-53982-w
Autor:
Kaly A. Mueller, Michael A. Schwarzschild, Rachit Bakshi, Eric J. Granucci, Yuehang Xu, Ghazaleh Sadri-Vakili, Sabrina Paganoni, Xiqun Chen
Publikováno v:
Molecular and Cellular Neuroscience. 92:12-16
Dominant mutations in an antioxidant enzyme superoxide dismutase-1 (SOD1) cause amyotrophic lateral sclerosis (ALS), an adult-onset neurodegenerative disease characterized by loss of motor neurons. Oxidative stress has also been linked to many of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7886e975c3cea29c817a7b3f5917f0b5
https://doi.org/10.1016/j.mcn.2018.06.002
https://doi.org/10.1016/j.mcn.2018.06.002
Autor:
Michael J. LaQuaglia, Marian DiFiglia, Remi A. Wilson, Kaly A. Mueller, Maria Iuliano, Khashayar Vakili, Adelaide Tousley, Kelly E. Glajch, Megan N. Huizenga, Eric J. Granucci, Kimberly B. Kegel-Gleason, Ghazaleh Sadri-Vakili, Elizabeth Weisman, Amanda M. Dios
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
The Hippo signaling pathway is involved in organ size regulation and tumor suppression. Although inhibition of Hippo leads to tumorigenesis, activation of Hippo may play a role in neurodegeneration. Specifically, activation of the upstream regulator,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef0b692a9aec14d4ee9aae2643e8fb7
https://doaj.org/article/cccd0dab16664adfba16dc950c90aec9
https://doaj.org/article/cccd0dab16664adfba16dc950c90aec9
Autor:
Kaly A. Mueller, Jonathan D. Glass, Paul Cernasov, Jacob M. Hooker, Alexandra N. Mills, Mohamad J. Alshikho, James D. Berry, Amanda M. Dios, Nicole R. Zürcher, Ghazaleh Sadri-Vakili, Tonya M. Gilbert, Eric J. Granucci, Suma Babu, Nazem Atassi
Publikováno v:
MusclenerveREFERENCES. 60(4)
Introduction There is an unmet need for mechanism-based biomarkers and effective disease modifying treatments in amyotrophic lateral sclerosis (ALS). Previous findings have provided evidence that histone deacetylases (HDAC) are altered in ALS, provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90352c95d32efaa8a37299a9d3f4a5aa
https://pubmed.ncbi.nlm.nih.gov/31241177
https://pubmed.ncbi.nlm.nih.gov/31241177
Autor:
Laurie J. Ozelius, Kelly E. Glajch, D. Cristopher Bragg, Geraldine Acuña, Edwin L. Muñoz, Regina Macalintal-Canlas, Christine A. Vaine, Naoto Ito, Nutan Sharma, Gierold Paul A. Legarda, Tiziana Petrozziello, Mark A. Ang, M. Salvie Velasco-Andrada, Ghazaleh Sadri-Vakili, Patrick J. Acuña, Cara Fernandez-Cerado, Alexandra N. Mills, Cid Czarina E. Diesta, William T. Hendriks, Kaly A. Mueller, Ellen B. Penney, Amanda M. Dios, Kotchaphorn Mangkalaphiban
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243655 (2020)
PLoS ONE
PLoS ONE
X-linked Dystonia-Parkinsonism (XDP) is a neurodegenerative disease linked to an insertion of a SINE-VNTR-Alu (SVA)-type retrotransposon within an intron of TAF1. This SVA insertion induces aberrant TAF1 splicing and partial intron retention, thereby
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08493bdf9097888220d01a44333daaa9
https://doi.org/10.1371/journal.pone.0243655
https://doi.org/10.1371/journal.pone.0243655
Autor:
Debra Ann Fadool, Pradeep G. Bhide, Megan N. Huizenga, Kaly A. Mueller, Deirdre M. McCarthy, Elisa N. Cannon, Genevieve A. Bell, Ghazaleh Sadri-Vakili
Publikováno v:
Developmental Neuroscience. 38:354-364
Prenatal cocaine exposure remains a major public health concern because of its adverse impact on cognitive function in children and adults. We report that prenatal cocaine exposure produces significant deficits in reversal learning, a key component o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::150e415c9ff5073272d21b9b0ee8b25c
https://doi.org/10.1159/000452739
https://doi.org/10.1159/000452739
Autor:
Rachit, Bakshi, Yuehang, Xu, Kaly A, Mueller, Xiqun, Chen, Eric, Granucci, Sabrina, Paganoni, Ghazaleh, Sadri-Vakili, Michael A, Schwarzschild
Publikováno v:
Molecular and cellular neurosciences. 92
Dominant mutations in an antioxidant enzyme superoxide dismutase-1 (SOD1) cause amyotrophic lateral sclerosis (ALS), an adult-onset neurodegenerative disease characterized by loss of motor neurons. Oxidative stress has also been linked to many of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c28a7d63b06ec29b3153cbe24c5a498
https://pubmed.ncbi.nlm.nih.gov/29928993
https://pubmed.ncbi.nlm.nih.gov/29928993