Výsledky vyhledávání - "Kalvin J. Gregory"

Akademický článek

Vitamin D binding protein-macrophage activating factor directly inhibits proliferation, migration, and uPAR expression of prostate cancer cells.

Autor: Kalvin J Gregory, Bing Zhao, Diane R Bielenberg, Sami Dridi, Jason Wu, Weihua Jiang, Bin Huang, Steven Pirie-Shepherd, Michael Fannon

Publikováno v: PLoS ONE, Vol 5, Iss 10, p e13428 (2010)

Vitamin D binding protein-macrophage activating factor (DBP-maf) is a potent inhibitor of tumor growth. Its activity, however, has been attributed to indirect mechanisms such as boosting the immune response by activating macrophages and inhibiting th

Externí odkaz: https://doaj.org/article/ca82440e47d146e885c818cf76de5cfa

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Real-time bioluminescent assay for inhibitors of RNA and DNA polymerases and other ATP-dependent enzymes

Autor: Valeri Golovlev, Kalvin J. Gregory, Nelson G. Chen, Ye Sun

Publikováno v: Analytical Biochemistry. 408:226-234

Viral polymerases are important targets for drug development. However, current methods used to identify and characterize inhibitors of polymerases are time-consuming, use radiolabeled reagents, and are cost-inefficient. Here we present a bioluminesce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed280ed93e540eda55dea9a7c8bc30a
https://doi.org/10.1016/j.ab.2010.08.016

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Gastroduodenal Crohn's Disease Is Associated With NOD2/CARD15Gene Polymorphisms, Particularly L1007PHomozygosity

Autor: Razvan Arsenescu, Lisbeth Selby, Willem J.S. de Villiers, Kalvin J. Gregory, Trevor A. Winter, Munira Nasser, Houssam E. Mardini

Publikováno v: Digestive Diseases and Sciences. 50:2316-2322

Limited data exist on the specific association between gastroduodenal Crohn's disease (GDCD) and NOD2/CARD15 gene polymorphisms. The aim of this study was to assess the association between NOD2 polymorphisms and GDCD, and to assess the specific assoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2138a52ef12c9f3936c9ce17afe9a58f
https://doi.org/10.1007/s10620-005-3054-2

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Use of a Biomimetic Peptide in the Design of a Competitive Binding Assay for Biotin and Biotin Analogues

Autor: Kalvin J. Gregory, Leonidas G. Bachas

Publikováno v: Analytical Biochemistry. 289:82-88

A competitive binding assay for biotin, biocytin, and desthiobiotin utilizing a genetically engineered enzyme-ligand conjugate is described herein. This assay is unique in that the enzyme-ligand conjugate consists of the streptavidin binding peptide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5968d554236b152d58529eda45580d67
https://doi.org/10.1006/abio.2000.4907

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Rapid and direct microRNA quantification by an enzymatic luminescence assay

Autor: Nelson G. Chen, Ye Sun, Val Golovlev, Kalvin J. Gregory

A quantitative bioluminescence assay for rapid and sensitive microRNA (miRNA) expression analysis was developed. The assay uses miRNA directly as a primer for binding to a circular single-stranded DNA template, followed by rolling circle amplificatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bcfb582ab09bba20164e182ba5ae2c
https://europepmc.org/articles/PMC3428512/

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Transient model of thermal deactivation of enzymes

Autor: Val Golovlev, Kalvin J. Gregory, Ye Sun, Nelson G. Chen

Publikováno v: Biochimica et biophysica acta. 1814(10)

The kinetics of enzyme deactivation provide useful insights on processes that determine the level of biological function of any enzyme. Photinus pyralis (firefly) luciferase is a convenient enzyme system for studying mechanisms and kinetics of enzyme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b342e1aa3e5037aa0d3c494d3f880fec
https://pubmed.ncbi.nlm.nih.gov/21749935

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Vitamin D binding protein-macrophage activating factor directly inhibits proliferation, migration, and uPAR expression of prostate cancer cells

Autor: Sami Dridi, Jason Wu, Weihua Jiang, Steven Pirie-Shepherd, Michael Fannon, Kalvin J. Gregory, Bin Huang, Diane R. Bielenberg, Bing Zhao

Publikováno v: PLoS ONE
PLoS ONE, Vol 5, Iss 10, p e13428 (2010)

Background: Vitamin D binding protein-macrophage activating factor (DBP-maf) is a potent inhibitor of tumor growth. Its activity, however, has been attributed to indirect mechanisms such as boosting the immune response by activating macrophages and i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f6b5fab018e4937e8c6afb3d690ae2
https://pubmed.ncbi.nlm.nih.gov/20976141

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Efficiency and specificity of microRNA-primed nucleotide analog incorporation by various DNA polymerases

Autor: Kalvin J. Gregory, Ye Sun, Val Golovlev

MicroRNAs (miRNAs) as endogenous regulators of gene expression have spurred a surge of interest for their quantification and expression analysis. High-sensitivity and high-specificity miRNA detection techniques, such as real-time polymerase chain rea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a9b6dffe4780b34712e58438a4455f
https://europepmc.org/articles/PMC3402025/

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