Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Kalpna Gupta"'
Autor:
Raghda T. Fouda, Hemanth M. Cherukury, Stacy B. Kiven, Natalie R. Garcia, Donovan A. Argueta, Graham J. Velasco, Kalpna Gupta, John D. Roberts
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
Externí odkaz:
https://doaj.org/article/04ef274fadd54fae957d85b78999f5e8
Autor:
Srideshikan Sargur Madabushi, Raghda Fouda, Hemendra Ghimire, Amr M. H. Abdelhamid, Ji Eun Lim, Paresh Vishwasrao, Stacy Kiven, Jamison Brooks, Darren Zuro, Joseph Rosenthal, Chandan Guha, Kalpna Gupta, Susanta K. Hui
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Sickle cell disease (SCD) is a serious global health problem, and currently, the only curative option is hematopoietic stem cell transplant (HCT). However, myeloablative total body irradiation (TBI)-based HCT is associated with high mortality/morbidi
Externí odkaz:
https://doaj.org/article/444c997c7da94b8dabe367640dc32352
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Treatment of severe chronic and acute pain in sickle cell disease (SCD) remains challenging due to the interdependence of pain and psychosocial modulation. We examined whether modulation of the descending pain pathway through an enriched die
Externí odkaz:
https://doaj.org/article/84f83814df994f77bfca2cd9aef03d4b
Autor:
Iryna A. Khasabova, Jacob Gable, Malcolm Johns, Sergey G. Khasabov, Alexander E. Kalyuzhny, Mikhail Y. Golovko, Svetlana A. Golovko, Stacy Kiven, Kalpna Gupta, Virginia S. Seybold, Donald A. Simone
Publikováno v:
Haematologica, Vol 108, Iss 3 (2022)
Sickle cell disease (SCD) is the most common inherited disease. Pain is a key morbidity of SCD and opioids are the main treatment but their side effects emphasize the need for new analgesic approaches. Humanized transgenic mouse models have been inst
Externí odkaz:
https://doaj.org/article/d52cf4b8931e4d4a97173e7e6f955e02
Autor:
Ann T. Farrell, Julie Panepinto, C. Patrick Carroll, Deepika S. Darbari, Ankit A. Desai, Allison A. King, Robert J. Adams, Tabitha D. Barber, Amanda M. Brandow, Michael R. DeBaun, Manus J. Donahue, Kalpna Gupta, Jane S. Hankins, Michelle Kameka, Fenella J. Kirkham, Harvey Luksenburg, Shirley Miller, Patricia Ann Oneal, David C. Rees, Rosanna Setse, Vivien A. Sheehan, John Strouse, Cheryl L. Stucky, Ellen M. Werner, John C. Wood, William T. Zempsky
Publikováno v:
Blood Advances, Vol 3, Iss 23, Pp 3982-4001 (2019)
Abstract: To address the global burden of sickle cell disease (SCD) and the need for novel therapies, the American Society of Hematology partnered with the US Food and Drug Administration to engage the work of 7 panels of clinicians, investigators, a
Externí odkaz:
https://doaj.org/article/94dcc43affc1405aa07a25c3738bac96
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1113 (2022)
Hemophilia is the most common X-linked bleeding diathesis caused by the genetic deficiency of coagulation factors VIII or IX. Despite treatment advances and improvements in clinical management to prevent bleeding, management of acute and chronic pain
Externí odkaz:
https://doaj.org/article/bf1cd24edca946bf9dd80c45074f5f6a
Autor:
Hassan Brim, James Taylor, Muneer Abbas, Kimberly Vilmenay, Mohammad Daremipouran, Sudhir Varma, Edward Lee, Betty Pace, Waogwende L Song-Naba, Kalpna Gupta, Sergei Nekhai, Patricia O'Neil, Hassan Ashktorab
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255956 (2021)
BackgroundSickle Cell Disease (SCD) is an inherited blood disorder that leads to hemolytic anemia, pain, organ damage and early mortality. It is characterized by polymerized deoxygenated hemoglobin, rigid sickle red blood cells and vaso-occlusive cri
Externí odkaz:
https://doaj.org/article/40c7f40e87fa4603ada768901c87aca0
Autor:
Gislaine Vieira-Damiani, Amanda Roberta de Almeida, Marilene Neves Silva, Bruno Groseli Lania, Tânia Cristina Benetti Soares, Marina Rovani Drummond, Karina A. Lins, Marna Ericson, Kalpna Gupta, Paulo Eduardo Neves Ferreira Velho
Publikováno v:
Revista do Instituto de Medicina Tropical de São Paulo, Vol 62 (2020)
ABSTRACT Bartonella spp. are re-emerging and neglected bacterial pathogens. The natural reservoirs for several species of this genus are domestic animals such as cats and dogs, the most common pets in the USA and Brazil. Some cat studies suggest that
Externí odkaz:
https://doaj.org/article/799b3b4f19334a01a98e8e4e32e181fa
Autor:
Stacy Kiven, Ying Wang, Anupam Aich, Donovan A. Argueta, Jianxun Lei, Varun Sagi, Madhushan Tennakoon, Saad J. Bedros, Nils Lambrecht, Kalpna Gupta
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Sickle cell disease (SCD) is a hemoglobinopathy affecting multiple organs and featuring acute and chronic pain. Purkinje cell damage and hyperalgesia have been demonstrated in transgenic sickle mice. Purkinje cells are associated with movement and ne
Externí odkaz:
https://doaj.org/article/83937e3586d4447abc4a71a565beb1c0
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Cannabidiol (CBD), the major non-psychoactive constituent of Cannabis sativa L., has gained traction as a potential treatment for intractable chronic pain in many conditions. Clinical evidence suggests that CBD provides therapeutic benefit in certain
Externí odkaz:
https://doaj.org/article/b629ae5bc0104c1abeffe3e34e5d6e86