Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kalpit Vora"'
Autor:
James Z. Deng, Zhifeng Chen, James Small, Yue Yuan, Kara Cox, Aimin Tang, Jeanette Roman, Liming Guan, Katrina Feller, Frances Ansbro, Kalpit Vora
Publikováno v:
Vaccines, Vol 12, Iss 5, p 469 (2024)
Multivalent pneumococcal vaccines have been developed successfully to combat invasive pneumococcal diseases (IPD) and reduce the associated healthcare burden. These vaccines employ pneumococcal capsular polysaccharides (PnPs), either conjugated or un
Externí odkaz:
https://doaj.org/article/198321ec85a749f19749c45e0baa8fb7
Autor:
Weifeng Xu, Brian Maas, Brad Roadcap, Aparna Swarup, Thomas Steinmetz, Linlin Luo, Marina Ichetovkin, Sandra Wood, Faye Vazvaei-Smith, Andrew Wen-Tseng Lee, Kalpit Vora, Roy Helmy
Publikováno v:
The AAPS Journal. 24
Historically, a neutralization antibody (NAb) assay is considered critical in immunogenicity assessment of biologic therapeutics, even with low anti-drug antibody (ADA) positive rates. In 2019, FDA new guidelines issued on immunogenicity testing ackn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b6c79bf73c34268b58a355f043f6cb
https://doi.org/10.1208/s12248-022-00753-7
https://doi.org/10.1208/s12248-022-00753-7
Autor:
Zhifeng Chen, Cox, Kara, Aimin Tang, Roman, Jeanette, Fink, Malorie, Kaufhold, Robin, Liming Guan, Xie, Andy, Boddicker, Melissa, Mcguinness, Debra, Xiao, Xiao, Hualin Li, Skinner, Julie, Verch, Thorsten, Retzlaff, Mary, Kalpit Vora
Figure S1. FACS sorting for single plasmablast cells. Freshly harvested peripheral blood mononuclear cells were stained with antibodies for flow cytometric detection of plasmablast cells. Plasmablasts were gated as shown, defined as lymphocytes/singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c2c790f0d8ac04d24a3671e6a38ff8
Autor:
Zhifeng Chen, Cox, Kara, Aimin Tang, Roman, Jeanette, Fink, Malorie, Kaufhold, Robin, Liming Guan, Xie, Andy, Boddicker, Melissa, Mcguinness, Debra, Xiao, Xiao, Hualin Li, Skinner, Julie, Verch, Thorsten, Retzlaff, Mary, Kalpit Vora
Figure S2. Crystal structure and model of two antibody Fabs with VH3/JH4 gernline usage bound to polysaccharides epitopes. Crystal structure of mAb 023.102 bound to RGP (PDB: 4HIJ) [32], shown in cartoon (A) and surface view (B). The model of mAb 1A6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14cf1f9d4f6917742bfbf3c79a9f0eff
Publikováno v:
Journal of Clinical Microbiology. 51:2970-2976
Pathogenic bacteria produce several virulence factors that help them establish infection in permissive hosts. Bacterial toxins are a major class of virulence factors and hence are attractive therapeutic targets for vaccine development. Here, we descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f75fb2e233c90fb5736108ae96abc0
https://doi.org/10.1128/jcm.01161-13
https://doi.org/10.1128/jcm.01161-13
Autor:
Christopher D. Benjamin, Sarah A. Bixler, Kalpit Vora, Jürg Tschopp, Jeffrey Thompson, Christine Ambrose, Catherine Hession, Martin L. Scott, Jeffrey L. Browning, Irene Sizing, Kathy Strauch, Mohammad Zafari, Pascal Schneider, Fang Qian, Teresa G. Cachero, Colleen Mullen
Publikováno v:
Science. 293:2108-2111
B cell homeostasis has been shown to critically depend on BAFF, the B cell activation factor from the tumor necrosis factor (TNF) family. Although BAFF is already known to bind two receptors, BCMA and TACI, we have identified a third receptor for BAF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3f49fedd3f751eedb5fd6d3b5f79ec
https://doi.org/10.1126/science.1061965
https://doi.org/10.1126/science.1061965
Publikováno v:
The Journal of Immunology. 194:72.20-72.20
Herpes Zoster (HZ) is a debilitating disease caused by reactivation of latent varicella-zoster virus (VZV). ZOSTAVAX is approved for the prevention of HZ and its complications in individuals 50 years and older in many countries around the world. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bc9435f3369556cfb920cccda629e60
https://doi.org/10.4049/jimmunol.194.supp.72.20
https://doi.org/10.4049/jimmunol.194.supp.72.20
Autor:
Kara Cox, Aimin Tang, Zhifeng Chen, Melanie Horton, Steven Meschino, Hao Yan, Xin-Min Wang, Sheri Dubey, Daniel DiStefano, Kalpit Vora
Publikováno v:
The Journal of Immunology. 194:212.15-212.15
Monitoring antigen-specific memory B cells and the antibodies they encode is important for understanding the specificity, breadth and duration of immune response to an infection or vaccination. The antibodies isolated could further help design vaccin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e57fcd3159a4b2ab7eac73a58b4c0d
https://doi.org/10.4049/jimmunol.194.supp.212.15
https://doi.org/10.4049/jimmunol.194.supp.212.15
Publikováno v:
The Journal of Immunology. 192:141.38-141.38
Zostavax© is a safe and effective vaccine against Herpes Zoster. The precise immune correlate of protection and the corresponding VZV antigens responsible for protective immunity are not currently defined. A few key pieces of data suggest that cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b410ec7aaa823e7ad7c400115092683
https://doi.org/10.4049/jimmunol.192.supp.141.38
https://doi.org/10.4049/jimmunol.192.supp.141.38