Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Kalpana Subedi"'
Autor:
Jie Wang, Indra Adrianto, Kalpana Subedi, Tingting Liu, Xiaojun Wu, Qijun Yi, Ian Loveless, Congcong Yin, Indrani Datta, Derek B. Sant’Angelo, Mitchell Kronenberg, Li Zhou, Qing-Sheng Mi
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-20 (2023)
Abstract Unlike conventional αβT cells, invariant natural killer T (iNKT) cells complete their terminal differentiation to functional iNKT1/2/17 cells in the thymus. However, underlying molecular programs that guide iNKT subset differentiation rema
Externí odkaz:
https://doaj.org/article/a8b94dfc61f84bf081361ad310518709
Autor:
Yotam Blech-Hermoni, Kalpana Subedi, Maya Silver, Leah Jensen, Stephen Coscia, Malcolm M. Kates, Yongmei Zhao, Castle Raley, Nancy Edwards, Bao Tran, Abhik Ray-Chaudhary, Pankaj Pathak, Ami Mankodi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract LIM domain-binding 3 (LDB3) is a member of the Enigma family of PDZ–LIM proteins. LDB3 has been reported as a striated muscle-specific Z-band alternatively spliced protein that plays an important role in mechanosensory actin cytoskeleton r
Externí odkaz:
https://doaj.org/article/9ee1bd97c6bb4527b3bc5e52e9a5cd0c
Autor:
Yi Yao, Kalpana Subedi, Tingting Liu, Namir Khalasawi, Carla Diana Pretto-Kernahan, Jesse William Wotring, Jie Wang, Congcong Yin, Aimin Jiang, Chunmei Fu, Peter Dimitrion, Jia Li, Jesse Veenstra, Qijun Yi, Kathy McKinnon, John Ernest McKinnon, Jonathan Zachary Sexton, Li Zhou, Qing-Sheng Mi
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-17 (2022)
Abstract Infection of human peripheral blood cells by SARS-CoV-2 has been debated because immune cells lack mRNA expression of both angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease type 2 (TMPRSS2). Herein we demonstrate that
Externí odkaz:
https://doaj.org/article/758f19306de54882a8f4a491d19b558b
Autor:
Jie Wang, Ian Loveless, Indra Adrianto, Tingting Liu, Kalpana Subedi, Xiaojun Wu, Md Moazzem Hossain, Eric Sebzda, Li Zhou, Qing-Sheng Mi
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-15 (2022)
Abstract Invariant natural killer T cell (iNKT) subsets are differentially distributed in various immune organs. However, it remains unclear whether iNKT cells exhibit phenotypical and functional differences in different peripheral organs and how thy
Externí odkaz:
https://doaj.org/article/809129ced6bd4a24a162722af3871383
Autor:
Pankaj Pathak, Yotam Blech-Hermoni, Kalpana Subedi, Jessica Mpamugo, Charissa Obeng-Nyarko, Rachel Ohman, Ilda Molloy, Malcolm Kates, Jessica Hale, Stacey Stauffer, Shyam K. Sharan, Ami Mankodi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Pathak et al. identify LDB3, a striated muscle PDZ-LIM protein, as a signaling adaptor in a major mechanosensor assembly through interactions with filamin C, HSPA8, and PKCα. When LDB3 is mutated, PKCα and TSC2-mTOR mediated homeostasis is impaired
Externí odkaz:
https://doaj.org/article/d4e302a88eb748a8be9622e9386d26e5
Autor:
Kalpana Subedi, Daniel Wall
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Myxobacteria exhibit a variety of complex social behaviors that all depend on coordinated movement of cells on solid surfaces. The cooperative nature of cell movements is known as social (S)-motility. This system is powered by cycles of type IV pili
Externí odkaz:
https://doaj.org/article/04b91c9eb3ae4775b4eb76aff27e79cc
Autor:
Yanying Liu, Kalpana Subedi, Aravind Baride, Svetlana Romanova, Eduardo Callegari, Christa C. Huber, Xuejun Wang, Hongmin Wang
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background Protein aggregates can be found in peripheral organs, such as the heart, kidney, and pancreas, but little is known about the impact of peripherally misfolded proteins on neuroinflammation and brain functional recovery following is
Externí odkaz:
https://doaj.org/article/adae44c44d014cad9a2f68bd4ac346e6
Autor:
Rajesh Balagam, Pengbo Cao, Govind P. Sah, Zhaoyang Zhang, Kalpana Subedi, Daniel Wall, Oleg A. Igoshin
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT A wide range of biological systems, from microbial swarms to bird flocks, display emergent behaviors driven by coordinated movement of individuals. To this end, individual organisms interact by recognizing their kin and adjusting their motil
Externí odkaz:
https://doaj.org/article/ca43289edc394db7b13d8a6f226fe59c
Autor:
Kalpana Subedi, Hongmin Wang
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 1, Pp 20-24 (2020)
Ischemic stroke is a global epidemic condition due to an inadequate supply of blood and oxygen to a specific area of brain either by arterial blockage or by narrowing of blood vessels. Despite having advancement in the use of thrombolytic and clot re
Externí odkaz:
https://doaj.org/article/90faf1200e8446b883344569174e9392
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that develop in the thymus through three maturation stages to acquire effector function and differentiate into MAIT1 (T-bet+) and MAIT17 (RORγt+) subsets. Upon activation, MAIT cell
Externí odkaz:
https://doaj.org/article/f40203452afb425082094d1d102ed418