Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Kalpana Raja"'
Autor:
Robert J. Millikin, Kalpana Raja, John Steill, Cannon Lock, Xuancheng Tu, Ian Ross, Lam C. Tsoi, Finn Kuusisto, Zijian Ni, Miron Livny, Brian Bockelman, James Thomson, Ron Stewart
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background The PubMed archive contains more than 34 million articles; consequently, it is becoming increasingly difficult for a biomedical researcher to keep up-to-date with different knowledge domains. Computationally efficient and interpre
Externí odkaz:
https://doaj.org/article/d8781b15ff3f482f95868b84ad1c6b1a
Autor:
Balu Bhasuran, Sharanya Manoharan, Oviya Ramalakshmi Iyyappan, Gurusamy Murugesan, Archana Prabahar, Kalpana Raja
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1535 (2024)
microRNA (miRNA)–messenger RNA (mRNA or gene) interactions are pivotal in various biological processes, including the regulation of gene expression, cellular differentiation, proliferation, apoptosis, and development, as well as the maintenance of
Externí odkaz:
https://doaj.org/article/29197c08ec304e2a855e642e7c885378
Autor:
Huishi Toh, Chentao Yang, Giulio Formenti, Kalpana Raja, Lily Yan, Alan Tracey, William Chow, Kerstin Howe, Lucie A. Bergeron, Guojie Zhang, Bettina Haase, Jacquelyn Mountcastle, Olivier Fedrigo, John Fogg, Bogdan Kirilenko, Chetan Munegowda, Michael Hiller, Aashish Jain, Daisuke Kihara, Arang Rhie, Adam M. Phillippy, Scott A. Swanson, Peng Jiang, Dennis O. Clegg, Erich D. Jarvis, James A. Thomson, Ron Stewart, Mark J. P. Chaisson, Yury V. Bukhman
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-21 (2022)
Abstract Background The Nile rat (Avicanthis niloticus) is an important animal model because of its robust diurnal rhythm, a cone-rich retina, and a propensity to develop diet-induced diabetes without chemical or genetic modifications. A closer simil
Externí odkaz:
https://doaj.org/article/9c728bac3c2c453abb352401d7a81103
Autor:
Archana Prabahar, Kalpana Raja
Publikováno v:
Diagnostics, Vol 12, Iss 8, p 1914 (2022)
Multiple sclerosis (MS), a chronic autoimmune disorder, affects the central nervous system of many young adults. More than half of MS patients develop cognition problems. Although several genomic and transcriptomic studies are currently reported in M
Externí odkaz:
https://doaj.org/article/12b2b56b0e5340abaf7da19857f72155
Autor:
Matthew T. Patrick, Philip E. Stuart, Kalpana Raja, Johann E. Gudjonsson, Trilokraj Tejasvi, Jingjing Yang, Vinod Chandran, Sayantan Das, Kristina Callis-Duffin, Eva Ellinghaus, Charlotta Enerbäck, Tõnu Esko, Andre Franke, Hyun M. Kang, Gerald G. Krueger, Henry W. Lim, Proton Rahman, Cheryl F. Rosen, Stephan Weidinger, Michael Weichenthal, Xiaoquan Wen, John J. Voorhees, Gonçalo R. Abecasis, Dafna D. Gladman, Rajan P. Nair, James T. Elder, Lam C. Tsoi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Approximately 30% of psoriasis patients develop psoriatic arthritis (PsA) and early diagnosis is crucial for the management of PsA. Here, Patrick et al. develop a computational pipeline involving statistical and machine-learning methods that can asse
Externí odkaz:
https://doaj.org/article/f67954f1b8fa41a1be488a5ddddc158b
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Adverse drug reactions (ADRs) pose critical public health issues, affecting over 6% of hospitalized patients. While knowledge of potential drug-drug interactions (DDI) is necessary to prevent ADR, the rapid pace of drug discovery makes it ch
Externí odkaz:
https://doaj.org/article/4ba7224201d24ca9b7d08693a91a8245
Autor:
Matthew T. Patrick, Philip E. Stuart, Kalpana Raja, Sunyi Chi, Zhi He, John J. Voorhees, Trilokraj Tejasvi, Johann E. Gudjonsson, J. Michelle Kahlenberg, Vinod Chandran, Proton Rahman, Dafna D. Gladman, Rajan P. Nair, James T. Elder, Lam C. Tsoi
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
We recently conducted a large association analysis to compare the genetic profiles between patients with psoriatic arthritis (PsA) and cutaneous-only psoriasis (PsC). Despite including over 7,000 genotyped patients, only the MHC achieved genome-wide
Externí odkaz:
https://doaj.org/article/80b4cbc08a6c4994af9ada4abecb3beb
Publikováno v:
International Journal of Genomics, Vol 2017 (2017)
In the past decade, the volume of “omics” data generated by the different high-throughput technologies has expanded exponentially. The managing, storing, and analyzing of this big data have been a great challenge for the researchers, especially w
Externí odkaz:
https://doaj.org/article/2d472c9bc1b7403a9669982a89811d57
Publikováno v:
Journal of Emergencies, Trauma and Shock, Vol 6, Iss 4, Pp 307-308 (2013)
Externí odkaz:
https://doaj.org/article/1d0a81a596684d3d81e201778517b02c
Publikováno v:
In Journal of Biomedical Informatics April 2015 54:121-131