Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kalpana Parvathaneni"'
Adoptive T cell immunotherapy for medullary thyroid carcinoma targeting GDNF family receptor alpha 4
Autor:
Vijay G. Bhoj, Lucy Li, Kalpana Parvathaneni, Zheng Zhang, Stephen Kacir, Dimitrios Arhontoulis, Kenneth Zhou, Bevin McGettigan-Croce, Selene Nunez-Cruz, Gayathri Gulendran, Alina C. Boesteanu, Laura Johnson, Michael D. Feldman, Enrico Radaelli, Keith Mansfield, MacLean Nasrallah, Rebecca S. Goydel, Haiyong Peng, Christoph Rader, Michael C. Milone, Don L. Siegel
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 387-398 (2021)
Metastatic medullary thyroid cancer (MTC) is a rare but often aggressive thyroid malignancy with a 5-year survival rate of less than 40% and few effective therapeutic options. Adoptive T cell immunotherapy using chimeric antigen receptor (CAR)-modifi
Externí odkaz:
https://doaj.org/article/21295495ac0b4d158ff8bf09829bb9f3
Autor:
Mireia Uribe-Herranz, Silvia Beghi, Marco Ruella, Kalpana Parvathaneni, Silvano Salaris, Nektarios Kostopoulos, Subin S. George, Stefano Pierini, Elisavet Krimitza, Francesca Costabile, Guido Ghilardi, Kimberly V. Amelsberg, Yong Gu Lee, Raymone Pajarillo, Caroline Markmann, Bevin McGettigan-Croce, Divyansh Agarwal, Noelle Frey, Simon F. Lacey, John Scholler, Khatuna Gabunia, Gary Wu, Elise Chong, David L. Porter, Carl H. June, Stephen J. Schuster, Vijay Bhoj, Andrea Facciabene
Publikováno v:
Molecular Therapy. 31:686-700
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f452ab38962928b51e549d95a9be6f55
https://doi.org/10.1016/j.ymthe.2023.01.012
https://doi.org/10.1016/j.ymthe.2023.01.012
Autor:
Andrea Facciabene, Mireia Uribe-Herranz, Silvia Beghi, Marco Ruella, Kalpana Parvathaneni, Guido Ghilrardi, Yung Gu Lee, Noelle Frey, John Scholler, Khatuna Gabunia, Research Specialist, Gary Wu, Elise Chong, David Porter, Carl June, Stephen Schuster, Vijay Bhoj
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48c41723db9655b41a9221d7b3daeed7
https://doi.org/10.1136/jitc-2022-sitc2022.0572
https://doi.org/10.1136/jitc-2022-sitc2022.0572
Autor:
Wei-Ting Hwang, Noelle V. Frey, Wenzhao Meng, Kalpana Parvathaneni, Ali Naji, Vijay Bhoj, Kyabeth Torres-Rodriguez
Publikováno v:
JAMA Oncol
This cohort study examines the ability of patients receiving chimeric antigen receptor T-cell treatments to mount T-cell immunity in response to messenger RNA vaccines for severe acute respiratory syndrome coronavirus 2 despite substantial B-cell dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70999645b0ff73a2258b0407ca505980
https://pubmed.ncbi.nlm.nih.gov/34792539
https://pubmed.ncbi.nlm.nih.gov/34792539
Autor:
Caroline Anna Markmann, Zheng Zheng, Ming Yu, Susan Rostami, Wei Wang, Trini Ochoa, Kalpana Parvathaneni, Xiaoming Xu, John Scholler, Qian Zhang, Avery Posey, David Allman, Michael Milone, Valder Arruda, Ben Samelson Jones, Ali Naji, Vijay Bhoj
Publikováno v:
The Journal of Immunology. 208:175.23-175.23
Pre-existing allo-antibodies (allo-Abs), that preclude transplant due to the risk of hyperacute rejection, lead to prolonged wait times and high mortality rates. Current desensitization approaches are ineffective as they do not adequately deplete all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c663a0ecbf71ce0d3b1635c3e5c424
https://doi.org/10.4049/jimmunol.208.supp.175.23
https://doi.org/10.4049/jimmunol.208.supp.175.23
Autor:
Katlyn Lederer, Emily Bettini, Kalpana Parvathaneni, Mark M. Painter, Divyansh Agarwal, Kendall A. Lundgreen, Madison Weirick, Kavitha Muralidharan, Diana Castaño, Rishi R. Goel, Xiaoming Xu, Elizabeth M. Drapeau, Sigrid Gouma, Jordan T. Ort, Moses Awofolaju, Allison R. Greenplate, Carole Le Coz, Neil Romberg, Jennifer Trofe-Clark, Gregory Malat, Lisa Jones, Mark Rosen, Daniela Weiskopf, Alessandro Sette, Behdad Besharatian, Mary Kaminiski, Scott E. Hensley, Paul Bates, E. John Wherry, Ali Naji, Vijay Bhoj, Michela Locci
Publikováno v:
Cell
medRxiv
medRxiv
Vaccine-mediated immunity often relies on the generation of protective antibodies and memory B cells, which commonly stem from germinal center (GC) reactions. An in-depth comparison of the GC responses elicited by SARS-CoV-2 mRNA vaccines in healthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8187f68a5022162d9568ba89d7235921
https://doi.org/10.1016/j.cell.2022.01.027
https://doi.org/10.1016/j.cell.2022.01.027
Adoptive T cell immunotherapy for medullary thyroid carcinoma targeting GDNF family receptor alpha 4
Autor:
Selene Nunez-Cruz, Michael Feldman, Kenneth Zhou, Christoph Rader, Haiyong Peng, Stephen Kacir, Keith Mansfield, Alina C. Boesteanu, Zheng Zhang, Enrico Radaelli, MacLean Nasrallah, Bevin McGettigan-Croce, Rebecca S. Goydel, Vijay Bhoj, Don L. Siegel, Michael C. Milone, Kalpana Parvathaneni, Gayathri Gulendran, Dimitrios Arhontoulis, Lucy Z. Li, Laura A. Johnson
Publikováno v:
Molecular Therapy Oncolytics
Molecular Therapy: Oncolytics, Vol 20, Iss, Pp 387-398 (2021)
Molecular Therapy: Oncolytics, Vol 20, Iss, Pp 387-398 (2021)
Metastatic medullary thyroid cancer (MTC) is a rare but often aggressive thyroid malignancy with a 5-year survival rate of less than 40% and few effective therapeutic options. Adoptive T cell immunotherapy using chimeric antigen receptor (CAR)-modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136615ee16ed55eb834ffa1e9b74f952
https://pubmed.ncbi.nlm.nih.gov/33614919
https://pubmed.ncbi.nlm.nih.gov/33614919
Autor:
Kalpana Parvathaneni, David W. Scott
Publikováno v:
Blood Advances. 2:2332-2340
Hemophilia A is an X-linked bleeding disorder caused by mutations in the factor VIII (FVIII) gene (F8). Treatment with recombinant or plasma-derived FVIII replacement therapy is standard therapy. A major problem in treating hemophilia A patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34a44c4b4ae3f8aab4432a923be657c
https://doi.org/10.1182/bloodadvances.2018018556
https://doi.org/10.1182/bloodadvances.2018018556
Autor:
Wenzhao Meng, Daniela Weiskopf, Michael R. Betts, Xiaoming Xu, James J. Knox, Kyabeth Toress-Rodriguez, Noelle V. Frey, Wei-Ting Hwang, Alfred L. Garfall, Ali Naji, Eline Luning-Prak, Vijay Bhoj, Carl H. June, Kalpana Parvathaneni, David L. Porter
Publikováno v:
Blood. 138:1757-1757
Abstract Background: The two FDA approved mRNA-based SARS-CoV2 vaccines have shown >90% efficacy at preventing COVID and eliciting protective immunity in nearly all healthy individuals. However, the extent of vaccine induced antibody and T cell immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abbf333debfcd453471507e027afe9b7
https://doi.org/10.1182/blood-2021-153730
https://doi.org/10.1182/blood-2021-153730
Autor:
Khatuna Gabunia, Stephen J. Schuster, Noelle V. Frey, David L. Porter, Nektarios Kostopoulos, Simon F. Lacey, Carl H. June, Andrea Facciabene, Raymone Pajarillo, Mireia Uribe-Herranz, Vijay Bhoj, Guido Ghilardi, Kalpana Parvathaneni, Elise A. Chong, John Scholler, Marco Ruella, Silvia Beghi, Yong Gu Gu Lee, Kimberly Amelsberg
Publikováno v:
Blood. 138:163-163
Background: Chimeric Antigen Receptor (CAR) T cell immunotherapy has revolutionized the treatment of B-cell malignancies. However, a significant subset of these patients either fails to respond or eventually relapses. Moreover, in solid cancers, CAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6205adfbf74d3ccd67a3ac6fa649709
https://doi.org/10.1182/blood-2021-151093
https://doi.org/10.1182/blood-2021-151093