Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kalpana, Surendranath"'
Autor:
Martin Andrs, Henriette Stoy, Barbora Boleslavska, Nagaraja Chappidi, Radhakrishnan Kanagaraj, Zuzana Nascakova, Shruti Menon, Satyajeet Rao, Anna Oravetzova, Jana Dobrovolna, Kalpana Surendranath, Massimo Lopes, Pavel Janscak
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Excessive oxidative stress is widely perceived as a key factor in cancer progression. Here, the authors reveal that oxidative stress induces transcription-dependent replication fork stalling that appears to be a major source of chromosomal rearrangem
Externí odkaz:
https://doaj.org/article/745c0a072ad8422ca874cba769fe660b
Autor:
Ahmed Sidali, Varsha Teotia, Nadeen Shaikh Solaiman, Nahida Bashir, Radhakrishnan Kanagaraj, John J. Murphy, Kalpana Surendranath
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 96, p 96 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Genome integrity must be tightly preserved to ensure cellular survival and to deter the genesis of disease. Endogenous and exogenous stressors that impose threats to genomic stability through DNA damage are counteracted by a tightly regulated DNA dam
Autor:
Anand Panchbhai, Munuse C Savash Ishanzadeh, Ahmed Sidali, Nadeen Solaiman, Smarana Pankanti, Radhakrishnan Kanagaraj, John J Murphy, Kalpana Surendranath
The cytokinesis block micronucleus assay is widely used for measuring/scoring/counting micronuclei, a marker of genome instability in cultured and primary cells. Though a gold standard method, this is a laborious and time-consuming process with perso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14b98b38c49f83641af0a1fa627cf67
https://doi.org/10.1101/2022.09.18.508405
https://doi.org/10.1101/2022.09.18.508405
Publikováno v:
Journal of inorganic biochemistry. 220
In recent years, fluorescent sensors have emerged as attractive imaging probes due to their distinct responses toward bio-relevant metal ions. However, the bioimaging application main barrier is the 'turn-off' response toward paramagnetic metal ions
In recent years, fluorescent sensors have emerged as attractive imaging probes due to their distinct responses toward bio-relevant metal ions. However, the bioimaging application main barrier is the ‘turn-off’ response toward paramagnetic metal i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660f6b4aaf9b7b546c2124b9742ae927
https://doi.org/10.1016/j.jinorgbio.2021.111466
https://doi.org/10.1016/j.jinorgbio.2021.111466
Autor:
Armando J. L. Pombeiro, Nadeen Shaikh Solaiman, Kalpana Surendranath, Anup Paul, Sellamuthu Anbu
Publikováno v:
Sensors and Actuators B: Chemical. 337:129785
Differential chemosensors have emerged as next-generation systems due to their simplicity and favourable responsive properties to produce different signals upon selective binding of various analytes simultaneously. Nevertheless, given their inadequat
Autor:
Ashima Bagaria, Suryanarayanarao Ramakumar, Anjali A. Karande, Udupi A. Ramagopal, Kalpana Surendranath
Publikováno v:
Journal of Biological Chemistry. 281:34465-34474
Abrin and agglutinin-I from the seeds of Abrus precatorius are type II ribosome-inactivating proteins that inhibit protein synthesis in eukaryotic cells. The two toxins share a high degree of sequence similarity; however, agglutinin-I is weaker in it
Publikováno v:
FEBS Letters. 579:1324-1331
Ribosome inactivating proteins (RIPs) are protein toxins that are of plant or microbial origin that inhibit protein synthesis by inactivating ribosomes. Recent studies suggest that RIPs are also capable of inducing cell death by apoptosis. Though man
Autor:
Zdenka Hasanova, Pavel Janscak, Kalpana Surendranath, Radhakrishnan Kanagaraj, Ian D. Hickson, Nagaraja Chappidi, Hana Sedlackova, Stefano Di Marco, Jana Langhoff, Veronika Altmannova, Stefano Ferrari, Lumir Krejci, Shruti Menon, Daniela Hühn, Victoria Marini, Rahul Bhowmick
Publikováno v:
Molecular Cell. 66:658-671.e8
The MUS81-EME1 endonuclease cleaves late replication intermediates at common fragile sites (CFSs) during early mitosis to trigger DNA-repair synthesis that ensures faithful chromosome segregation. Here, we show that these DNA transactions are promote
Autor:
Anjali A. Karande, Chelliah Jayabaskaran, Balabhadrapatruni V. S. K. Chakravarthi, Kalpana Surendranath, Prasanta Kumar Das
Publikováno v:
Journal of biosciences. 33(2)
A fungus was isolated from the stem cuttings of Taxus celebica, which produced paclitaxel in liquid-grown cultures. The fungus was identified as Fusarium solani based on colony characteristics, morphology of conidia and the 26S rDNA sequence. Paclita