Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kalpana, Lal"'
Autor:
Robert E. Sinden, Richard D. Oakes, Sanya J. Sanderson, Kalpana Lal, Jonathan M. Wastling, John R. Yates, Dominic Kurian, Lawrence G. Hunt, Judith Helena Prieto, Fiona M. Tomley, Elizabeth Bromley
We report the proteomes of four life-cycle stages of the Apicomplexan parasite Eimeria tenella. A total of 1868 proteins were identified, with 630, 699, 845 and 1532 found in early oocysts (unsporulated), late oocysts (sporulated), sporozoites and se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aef221df980ebb503a2a927e0cff7b0
https://ora.ox.ac.uk/objects/uuid:c71b667b-b875-4a2c-957b-931cab38c4a2
https://ora.ox.ac.uk/objects/uuid:c71b667b-b875-4a2c-957b-931cab38c4a2
Autor:
Fiona M. Tomley, Elizabeth Bromley, Sanya J. Sanderson, Jonathan M. Wastling, Judith Helena Prieto, John R. Yates, Kalpana Lal, Robert E. Sinden
Secretion of microneme proteins is essential to Plasmodium invasion but the molecular composition of these secretory organelles remains poorly defined. Here, we describe the first Plasmodium microneme proteome. Purification of micronemes by subcellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c2baaa7d8e3c7f0a076d0033d6af4e
https://ora.ox.ac.uk/objects/uuid:9c87a2cf-587b-47e9-b744-f09b2ac25868
https://ora.ox.ac.uk/objects/uuid:9c87a2cf-587b-47e9-b744-f09b2ac25868
Autor:
D Raine, Arthur M. Talman, Kalpana Lal, Michael J.E. Sternberg, Fiona M. Tomley, Rebecca Limenitakis Stanway, John R. Yates, Robert E. Sinden, Mark N. Wass, Andrew M. Blagborough, Judith Helena Prieto
Publikováno v:
Parasitology; Vol 139
Parasitology
Wass, M N; Limenitakis Stanway, Rebecca; Blagborough, A M; Lal, K; Prieto, J H; Raine, D; Sternberg, M J E; Talman, A M; Tomley, F; Yates, J; Sinden, R E (2012). Proteomic analysis of Plasmodium in the mosquito: progress and pitfalls. Parasitology, 139(9), pp. 1131-1145. Cambridge University Press 10.1017/S0031182012000133
Parasitology
Wass, M N; Limenitakis Stanway, Rebecca; Blagborough, A M; Lal, K; Prieto, J H; Raine, D; Sternberg, M J E; Talman, A M; Tomley, F; Yates, J; Sinden, R E (2012). Proteomic analysis of Plasmodium in the mosquito: progress and pitfalls. Parasitology, 139(9), pp. 1131-1145. Cambridge University Press 10.1017/S0031182012000133
SUMMARYHere we discuss proteomic analyses of whole cell preparations of the mosquito stages of malaria parasite development (i.e. gametocytes, microgamete, ookinete, oocyst and sporozoite) of Plasmodium berghei. We also include critiques of the prote
Autor:
Fontje Kaligis, D. Timothy J. Littlewood, Suzanne T. Williams, Kalpana Lal, David G. Reid, Jacqueline Mackenzie-Dodds
Publikováno v:
Journal of Biogeography. 33:990-1006
Aim This study aimed to test monophyly and geographical boundaries in five marine intertidal snail species from the central Indo-West Pacific. We tested the prediction that phylogenetic breaks between the Indian and Pacific Ocean basins should be mor
Autor:
Yasufumi Imanaka, Paula H B Bolton-Maggs, Edward G. D. Tuddenham, John H. McVey, Geoffrey Kemball-Cook, Kalpana Lal
Publikováno v:
Thrombosis and Haemostasis. 93:1082-1088
SummaryPCR-SSCP and DNA sequence analysis of a factor XI (FXI) deficient patient (FXI:C 39 U/dL; FXI:Ag 27 U/dL) identified a C to T transition in exon 12 of the FXI gene (F11 c.1521C>T) that predicts the substitution of Thr475 by Ile (FXIT475I) with
Autor:
Robert P. Hirt, Mark C. Field, TM Embley, B Healy, Graham H. Coombs, Kalpana Lal, J Pinxteren, Jim Warwicker
Publikováno v:
Molecular and Biochemical Parasitology. 129:179-189
We have cloned a single copy gene from the human parasite Trichomonas vaginalis that encodes a putative protein of 402 amino acids with approximately 35% sequence identity to known alpha subunits of heterotrimeric G-proteins. It contains the characte
Autor:
Colin J. Davidson, Edward G. D. Tuddenham, John H. McVey, Philip Snell, Robert P. Hirt, Kalpana Lal, Greg Elgar
Publikováno v:
Thrombosis and Haemostasis. 89:420-428
SummaryIn mammalian blood coagulation 5 proteases, factor VII (FVII), factor IX (FIX), factor X (FX), protein C (PC) and prothrombin act with two cofactors factor V and factor VIII to control the generation of fibrin. Biochemical evidence and molecul
Autor:
Andrew M, Blagborough, Michael J, Delves, Chandra, Ramakrishnan, Kalpana, Lal, Geoffrey, Butcher, Robert E, Sinden
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 923
Here we describe a series of methods that can be used to assess the activities of "vaccines," drugs, and genetically modified vectors, for their abilities to inhibit transmission of Plasmodium from its vertebrate to its mosquito hosts. The selection
Autor:
Kalpana Lal, Kenneth W. Baker, Andrew M. Blagborough, Robert E. Sinden, Chandra Ramakrishnan, Michael J. Delves, Geoffrey Butcher
Publikováno v:
Methods in Molecular Biology ISBN: 9781627030250
We provide a series of protocols that have been used for the cyclic transmission of rodent malaria parasites in the laboratory. This is now possible both in vivo and in vitro. We focus on the least "resource intensive" and generic methods that we fin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc3f7350e9fdb5267b041653d5b6826
https://doi.org/10.1007/978-1-62703-026-7_5
https://doi.org/10.1007/978-1-62703-026-7_5
Autor:
Robert E. Sinden, Jonathan M. Wastling, Kalpana Lal, Elizabeth Bromley, Michael J. Delves, Fiona M. Tomley
Publikováno v:
International journal for parasitology. 39(7)
Successful development of Plasmodium sexual stages is essential for parasite survival, but the genes involved are poorly understood. We 'knocked out' the male development gene-1 (mdv-1) locus in Plasmodium berghei and found it to be important in fema