Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Kalluri Subba Rao"'
Publikováno v:
Mechanisms of Ageing and Development. 133:203-213
Topoisomerase IIβ (TopoIIβ), an enzyme involved in DNA rearrangements, is predominantly present in brain and its levels are shown to decrease with age. This study characterizes the function of TopoIIβ in regulating BER (base excision repair) activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27bf2e2f7906f804883ec787a2ddcc57
https://doi.org/10.1016/j.mad.2012.03.010
https://doi.org/10.1016/j.mad.2012.03.010
Publikováno v:
Neurochemical research. 41(1-2)
It is well established now that dietary calorie restriction (CR) leads to extension of life span in many species, although the exact mechanism of this effect is still eluding. In the present study, we examined the effect of 40 % CR imposed during a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bcd3e9221461fa3972c7970fefdffa
https://pubmed.ncbi.nlm.nih.gov/26801173
https://pubmed.ncbi.nlm.nih.gov/26801173
Autor:
Kalluri Subba Rao
Publikováno v:
Proceedings of Indian National Science Academy, Vol 56, Iss 1B (2015)
DNA -Repair in Developing and Aging Brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::2267dd01e08ad9cc9e9bc079d07d3105
https://insa.nic.in/writereaddata/UpLoadedFiles/PINSA/Vol56B_1990_1_Art17.pdf
https://insa.nic.in/writereaddata/UpLoadedFiles/PINSA/Vol56B_1990_1_Art17.pdf
Autor:
Kalluri Subba Rao
Publikováno v:
Proceedings of Indian National Science Academy, Vol 69, Iss 2B (2015)
DNA-Repair and Brain Aging: The Importance of Base Excision Repair and DNA Polymerase ?
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::2403db5ea02479d8765d82baf571cd6a
https://insa.nic.in/writereaddata/UpLoadedFiles/PINSA/Vol69B_2003_2_Art02.pdf
https://insa.nic.in/writereaddata/UpLoadedFiles/PINSA/Vol69B_2003_2_Art02.pdf
Publikováno v:
Annals of the New York Academy of Sciences. 928:113-120
A close relationship between the DNA repair potential of various organisms and their rate of aging has been long suspected. We have been looking into the steps of the DNA repair process in isolated neurons from rats of different ages. Unscheduled DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67732a35cda458228ad67f1c31c52723
https://doi.org/10.1111/j.1749-6632.2001.tb05641.x
https://doi.org/10.1111/j.1749-6632.2001.tb05641.x
Publikováno v:
Neurochemical Research. 29:761-770
A three-step reaction strategy has been developed to examine the mechanism of extension of a mismatched primer in an oligoduplex substrate by rat neuronal extracts and DNA polymerase beta. The results revealed that in the case of duplexes with a mism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9b3d98a2b34da191d1ef072d3d3020
https://doi.org/10.1023/b:nere.0000018848.58358.95
https://doi.org/10.1023/b:nere.0000018848.58358.95
Autor:
Kalluri Subba Rao
Publikováno v:
Molecular and Cellular Biochemistry. 253:313-318
It is now well established, in many species, that dietary calorie restriction confers beneficial effects like slowing down many age dependent processes and extending the lifespan. There are indications that this phenomenon may be applicable even in n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::463c7a918be28bd15dbc6c8999864a0f
https://doi.org/10.1023/a:1026084420943
https://doi.org/10.1023/a:1026084420943
Publikováno v:
International Journal of Developmental Neuroscience. 20:491-496
The relative proportions of DNA-polymerases alpha, beta, delta and epsilon (pols alpha, beta, delta and epsilon ) activities in isolated neuronal and astroglial cell fractions from developing, adult and aging rat brain cerebral cortex, were examined.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7987bdc5bde2d4542736c7f21ebe4bf3
https://doi.org/10.1016/s0736-5748(02)00079-5
https://doi.org/10.1016/s0736-5748(02)00079-5
Publikováno v:
Molecular Brain Research. 85:251-259
Synthetic staggered oligodeoxynucleotide duplexes are formed by annealing a 5'-32P-labeled 14-mer with four different 21-mers. These duplexes have either a correct or mismatched base pair at 3'-end of the primer. With these model template primers the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5cbed4ff19da6aaf61c9720cae2f4b0
https://doi.org/10.1016/s0169-328x(00)00266-7
https://doi.org/10.1016/s0169-328x(00)00266-7
Publikováno v:
Mechanisms of Ageing and Development. 104:133-148
Clinically healthy subjects of the Indian population were divided into three age groups: young, 8–14 years; adult, 20–35 years; old, ≥55 years and were further classified based on body mass index (BMI) as normal BMI (NBMI) ≥20 and low BMI (LB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4dfc9095e23c06ae40500519b2b215d
https://doi.org/10.1016/s0047-6374(98)00062-1
https://doi.org/10.1016/s0047-6374(98)00062-1