Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Kallol, Dutta"'
Autor:
Silvia Pozzi, Philippe Codron, Geneviève Soucy, Laurence Renaud, Pierre Junior Cordeau, Kallol Dutta, Christine Bareil, Jean-Pierre Julien
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), 2 incurable neurodegenerative disorders, share the same pathological hallmark named TDP43 (TAR DNA binding protein 43) proteinopathy. This event is characterized by a c
Externí odkaz:
https://doaj.org/article/391ef4200f894d238d6e9a4e2922fd24
Autor:
Anirban Basu, Kallol Dutta
Publikováno v:
F1000Research, Vol 6 (2017)
Japanese encephalitis is a flaviviral disease that is endemic to the South, Southeast Asia, and Asia Oceania regions. Given that about 60% of the world’s population (about 7.4 billion) resides in this region (about 4.4 billion), this disease poses
Externí odkaz:
https://doaj.org/article/37ea34c39a654e81ab48ee8a6e7948a6
Autor:
Arshed Nazmi, Sriparna Mukherjee, Kiran Kundu, Kallol Dutta, Anita Mahadevan, Susarla Krishna Shankar, Anirban Basu
Publikováno v:
Neurobiology of Disease, Vol 69, Iss , Pp 235-247 (2014)
Toll-like receptor 7 (TLR7) known to recognize guanidine-rich ssRNA has been shown to mount vital host defense mechanism against many viruses including flaviviruses. Signal transduction through TLR7 has been shown to produce type-1 interferon and pro
Externí odkaz:
https://doaj.org/article/1a89d8dcb5f24398a00b30fef650081c
Publikováno v:
The Journal of Neuroscience
J Neurosci
J Neurosci
To investigate the role of neuronal NF-κB activity in pathogenesis of amyotrophic lateral sclerosis (ALS), we generated transgenic mice with neuron-specific expression of a super-repressor form of the NF-κB inhibitor (IκBα-SR), which were then cr
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140248 (2015)
TAR DNA-binding protein 43 (TDP-43) is a major component in aggregates of ubiquitinated proteins in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Here we report that lipopolysaccharide (LPS)-induced inflammation ca
Externí odkaz:
https://doaj.org/article/0c468c49924f49bc8178637f5497cf65
Autor:
Jean-Pierre Julien, Silvia Pozzi, Christine Bareil, Philippe Codron, Pierre Cordeau, Kallol Dutta, Laurence Renaud, Geneviève Soucy
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
JCI Insight
JCI Insight
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), 2 incurable neurodegenerative disorders, share the same pathological hallmark named TDP43 (TAR DNA binding protein 43) proteinopathy. This event is characterized by a c
Publikováno v:
Experimental Neurology. 309:193-204
Withania somnifera (WS; commonly known as Ashwagandha or Indian ginseng) is a medicinal plant whose extracts have been in use for centuries in various regions of the world as a rejuvenator. There is now a growing body of evidence documenting neuropro
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17225 (2011)
Japanese encephalitis virus (JEV) induces neuroinflammation with typical features of viral encephalitis, including inflammatory cell infiltration, activation of microglia, and neuronal degeneration. The detrimental effects of inflammation on neurogen
Externí odkaz:
https://doaj.org/article/0e986c457d5543b196882797ee09df9a
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21761 (2011)
Neuroinflammation associated with Japanese encephalitis (JE) is mainly due to the activation of glial cells with subsequent release of proinflammatory mediators from them. The recognition of viral RNA, in part, by the pattern recognition receptor ret
Externí odkaz:
https://doaj.org/article/cc43aa3687db481684eb26868f0d6be9
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e9984 (2010)
BACKGROUND: Benzo[a]pyrene (B[a]P) belongs to a class of polycyclic aromatic hydrocarbons that serve as micropollutants in the environment. B[a]P has been reported as a probable carcinogen in humans. Exposure to B[a]P can take place by ingestion of c
Externí odkaz:
https://doaj.org/article/41ad01ce50ee400fbb954bd858ed4fca