Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kallivalappil T. Santhosh"'
Autor:
Scott Dyck, Hardeep Kataria, Arsalan Alizadeh, Kallivalappil T. Santhosh, Bradley Lang, Jerry Silver, Soheila Karimi-Abdolrezaee
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-26 (2018)
Abstract Background Traumatic spinal cord injury (SCI) results in upregulation of chondroitin sulfate proteoglycans (CSPGs) by reactive glia that impedes repair and regeneration in the spinal cord. Degradation of CSPGs is known to be beneficial in pr
Externí odkaz:
https://doaj.org/article/f229e37bd17e4dbd8efbc1308c6622a5
Autor:
Arsalan Alizadeh, Kallivalappil T. Santhosh, Hardeep Kataria, Abdelilah S. Gounni, Soheila Karimi-Abdolrezaee
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-21 (2018)
Abstract Background Spinal cord injury (SCI) triggers a robust neuroinflammatory response that governs secondary injury mechanisms with both degenerative and pro-regenerative effects. Identifying new immunomodulatory therapies to promote the supporti
Externí odkaz:
https://doaj.org/article/33fc3077f2a34fd180271bd9c9d76622
Autor:
Soheila Karimi-Abdolrezaee, Arsalan Alizadeh, Hardeep Kataria, Scott M. Dyck, Kallivalappil T. Santhosh, Ghazaleh M. Shahriary, Dung H. Nguyen
Publikováno v:
Glia. 65:1152-1175
Spinal cord injury (SCI) results in glial activation and neuroinflammation, which play pivotal roles in the secondary injury mechanisms with both pro- and antiregeneration effects. Presently, little is known about the endogenous molecular mechanisms
Autor:
Arsalan Alizadeh, Hardeep Kataria, Jerry Silver, Soheila Karimi-Abdolrezaee, Scott M. Dyck, Bradley T. Lang, Kallivalappil T. Santhosh
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-26 (2018)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Traumatic spinal cord injury (SCI) results in upregulation of chondroitin sulfate proteoglycans (CSPGs) by reactive glia that impedes repair and regeneration in the spinal cord. Degradation of CSPGs is known to be beneficial in promoting e
Autor:
Abdelilah S. Gounni, Hardeep Kataria, Soheila Karimi-Abdolrezaee, Arsalan Alizadeh, Kallivalappil T. Santhosh
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-21 (2018)
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-21 (2018)
Background Spinal cord injury (SCI) triggers a robust neuroinflammatory response that governs secondary injury mechanisms with both degenerative and pro-regenerative effects. Identifying new immunomodulatory therapies to promote the supportive aspect
Autor:
Scott M. Dyck, Soheila Karimi-Abdolrezaee, Evan H. Proulx, Arsalan Alizadeh, Chia-Lun Wu, Kallivalappil T. Santhosh
Publikováno v:
Stem Cells. 33:2550-2563
Multipotent adult neural precursor cells (NPCs) have tremendous intrinsic potential to repair the damaged spinal cord. However, evidence shows that the regenerative capabilities of endogenous and transplanted NPCs are limited in the microenvironment
Autor:
Hardeep Kataria, Soheila Karimi-Abdolrezaee, Ghazaleh M. Shahriary, Ryan Nathan Henrie, James A. Thliveris, Arsalan Alizadeh, Shekoofeh Saboktakin Rizi, Kallivalappil T. Santhosh
Publikováno v:
Glia. 66(3)
Oligodendroglial cell death and demyelination are hallmarks of neurotrauma and multiple sclerosis that cause axonal damage and functional impairments. Remyelination remains a challenge as the ability of endogenous precursor cells for oligodendrocyte