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pro vyhledávání: '"Kalliopi Skamaki"'
Autor:
Daniel Cannon, Bojana Popovic, D. Gareth Rees, Ralph Minter, Andrew Buchanan, Kalliopi Skamaki, Stéphane Emond, John Andrews, Florian Hollfelder, Matthieu Chodorge
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences
We report a systematic combinatorial exploration of affinity enhancement of antibodies by insertions and deletions (InDels). Transposon-based introduction of InDels via the method TRIAD (transposition-based random insertion and deletion mutagenesis)
Autor:
Bojana Popovic, Matthieu Chodorge, John Andrews, Kalliopi Skamaki, Stéphane Emond, Florian Hollfelder, Ralph Minter, Daniel Cannon, D. Gareth Rees, Andrew Buchanan
We report the first systematic combinatorial exploration of affinity enhancement of antibodies by insertions and deletions (InDels). Transposon-based introduction of InDels via the method TRIAD was used to generate large libraries with random in-fram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89427c3e68fe19a5e3e54d9fc032bf0
https://doi.org/10.1101/2020.04.26.062786
https://doi.org/10.1101/2020.04.26.062786