Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Kalle T Rytkönen"'
Autor:
Kalle T Rytkönen
Publikováno v:
eLife, Vol 7 (2018)
The biology of sponges provides clues about how early animals may have dealt with low levels of oxygen.
Externí odkaz:
https://doaj.org/article/8e4d9ff4fdfb4a459962a4cc6b2386ca
Autor:
Tommi Välikangas, Sini Junttila, Kalle T. Rytkönen, Anu Kukkonen-Macchi, Tomi Suomi, Laura L. Elo
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading across the world despite vast global vaccination efforts. Consequently, many studies have looked for potential human host
Externí odkaz:
https://doaj.org/article/367976d8dab74a4e87e379a4df86ddcc
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2588-2596 (2021)
Single-cell omics technologies are currently solving biological and medical problems that earlier have remained elusive, such as discovery of new cell types, cellular differentiation trajectories and communication networks across cells and tissues. C
Externí odkaz:
https://doaj.org/article/d9d532e9c56141948879afa6b1d99640
Publikováno v:
Biology Open, Vol 11, Iss 4 (2022)
Clustering of cells based on gene expression is one of the major steps in single-cell RNA-sequencing (scRNA-seq) data analysis. One key challenge in cluster analysis is the unknown number of clusters and, for this issue, there is still no comprehensi
Externí odkaz:
https://doaj.org/article/e1ea61a2e7da43dcbe435faa46ee01af
Autor:
Kalle T, Rytkönen
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.)References.
Menstrual cycle is a major determinant in female reproductive health. In a recent report, Mao et al. (2022) associated deficient glycolysis with heavy menstrual bleeding. This commentary summarizes these recent findings and the importance of glycolys
Autor:
Matti Poutanen, Xinghong Ma, Antti Perheentupa, Mehrad Mahmoudian, Günter P. Wagner, Kalle T. Rytkönen, Taija Heinosalo, Laura L. Elo
Publikováno v:
Reproduction. 160:39-51
Human reproductive success depends on a properly decidualized uterine endometrium that allows implantation and the formation of the placenta. At the core of the decidualization process are endometrial stromal fibroblasts (ESF) that differentiate to d
Autor:
Poutanen, Taija Heinosalo, Kalle T. Rytkönen, Niina Saarinen, Päivi Järvensivu, Pauliina Damdimopoulou, Leena Strauss, Satu Orasniemi, Petricia Horshauge, Michael Gabriel, Pasi Koskimies, Claes Ohlsson, Pauliina Kronqvist, Matti
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4815
Hydroxysteroid (17beta) dehydrogenase type 1 (HSD17B1) is an enzyme that converts estrone to estradiol, while adenomyosis is an estrogen-dependent disease with poorly understood pathophysiology. In the present study, we show that mice universally ove
Autor:
Taija, Heinosalo, Kalle T, Rytkönen, Niina, Saarinen, Päivi, Järvensivu, Pauliina, Damdimopoulou, Leena, Strauss, Satu, Orasniemi, Petricia, Horshauge, Michael, Gabriel, Pasi, Koskimies, Claes, Ohlsson, Pauliina, Kronqvist, Matti, Poutanen
Publikováno v:
International journal of molecular sciences. 23(9)
Hydroxysteroid (17beta) dehydrogenase type 1 (HSD17B1) is an enzyme that converts estrone to estradiol, while adenomyosis is an estrogen-dependent disease with poorly understood pathophysiology. In the present study, we show that mice universally ove
Autor:
Kalle T Rytkönen, Nigatu Adossa, Mehrad Mahmoudian, Tapio Lönnberg, Matti Poutanen, Laura L Elo
Publikováno v:
Reproduction (Cambridge, England). 164(5)
In brief Preeclampsia is a common serious disorder that can occur during pregnancy. This study uses integrative analysis of preeclampsia transcriptomes and single-cell transcriptomes to predict cell type-specific contributions to preeclampsia. Abstra
Autor:
Kalle T, Rytkönen, Thomas, Faux, Mehrad, Mahmoudian, Taija, Heinosalo, Mauris C, Nnamani, Antti, Perheentupa, Matti, Poutanen, Laura L, Elo, Günter P, Wagner
Publikováno v:
iScience. 25(5)
Trimethylation of histone H3 at lysine 4 (H3K4me3) is a marker of active promoters. Broad H3K4me3 promoter domains have been associated with cell type identity, but H3K4me3 dynamics upon cellular stress have not been well characterized. We assessed t