Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Kalle, Saksela"'
Autor:
Anna R. Mäkelä, Hasan Uğurlu, Liina Hannula, Ravi Kant, Petja Salminen, Riku Fagerlund, Sanna Mäki, Anu Haveri, Tomas Strandin, Lauri Kareinen, Jussi Hepojoki, Suvi Kuivanen, Lev Levanov, Arja Pasternack, Rauno A. Naves, Olli Ritvos, Pamela Österlund, Tarja Sironen, Olli Vapalahti, Anja Kipar, Juha T. Huiskonen, Ilona Rissanen, Kalle Saksela
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Here the authors describe a small antibody-like protein that can prevent infection by diverse SARS-CoV-2 variants in cell culture and in mice that were intranasally treated with this inhibitor before or shortly after being exposed to the virus.
Externí odkaz:
https://doaj.org/article/326654b56d2c4bd89b56074f0855fd2f
Autor:
Aino Sormunen, Emma Koivulehto, Kari Alitalo, Kalle Saksela, Nihay Laham-Karam, Seppo Ylä-Herttuala
Publikováno v:
Methods and Protocols, Vol 6, Iss 2, p 43 (2023)
Traditional Western blotting is one of the most used analytical techniques in biological research. However, it can be time-consuming and suffer from a lack of reproducibility. Consequently, devices with different degrees of automation have been devel
Externí odkaz:
https://doaj.org/article/f68c0468b3ae4e0494232fc24e499330
Autor:
Senem Merve Fred, Suvi Kuivanen, Hasan Ugurlu, Plinio Cabrera Casarotto, Lev Levanov, Kalle Saksela, Olli Vapalahti, Eero Castrén
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Repurposing of currently available drugs is a valuable strategy to tackle the consequences of COVID-19. Recently, several studies have investigated the effect of psychoactive drugs on SARS-CoV-2 in cell culture models as well as in clinical practice.
Externí odkaz:
https://doaj.org/article/0cd2d56649b04388869f8e290921e48b
Autor:
Zhe Zhao, Riku Fagerlund, Helena Tossavainen, Kristina Hopfensperger, Rishikesh Lotke, Smitha Srinivasachar Badarinarayan, Frank Kirchhoff, Perttu Permi, Kei Sato, Daniel Sauter, Kalle Saksela
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1009728 (2021)
The accessory protein Nef of human and simian immunodeficiency viruses (HIV and SIV) is an important pathogenicity factor known to interact with cellular protein kinases and other signaling proteins. A canonical SH3 domain binding motif in Nef is req
Externí odkaz:
https://doaj.org/article/1318f37ecbe84d2aabcfcf4234f5b6b8
Autor:
Juuso Rusanen, Lauri Kareinen, Leonora Szirovicza, Hasan Uğurlu, Lev Levanov, Anu Jääskeläinen, Maarit Ahava, Satu Kurkela, Kalle Saksela, Klaus Hedman, Olli Vapalahti, Jussi Hepojoki
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
PCR is currently the gold standard for the diagnosis of many acute infections. While PCR and its variants are highly sensitive and specific, the time from sampling to results is measured in hours at best.
Externí odkaz:
https://doaj.org/article/7af21c093fd846b4a1d880d3b2fd06eb
Autor:
Mikael Knip, Anna Parviainen, Maaret Turtinen, Anna But, Taina Härkönen, Jussi Hepojoki, Tarja Sironen, Rommel Iheozor-Ejiofor, Hasan Uğurlu, Kalle Saksela, Johanna Lempainen, Jorma Ilonen, Olli Vapalahti
Publikováno v:
The Lancet Diabetes & Endocrinology. 11:251-260
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d647c8d4c1f5b1116e2ad985b7565167
https://doi.org/10.1016/s2213-8587(23)00041-4
https://doi.org/10.1016/s2213-8587(23)00041-4
Autor:
Ravi Kant, Lauri Kareinen, Teemu Smura, Tobias L. Freitag, Sawan Kumar Jha, Kari Alitalo, Seppo Meri, Tarja Sironen, Kalle Saksela, Tomas Strandin, Anja Kipar, Olli Vapalahti
Publikováno v:
Viruses, Vol 13, Iss 11, p 2263 (2021)
Small animal models are of crucial importance for assessing COVID-19 countermeasures. Common laboratory mice would be well-suited for this purpose but are not susceptible to infection with wild-type SARS-CoV-2. However, the development of mouse-adapt
Externí odkaz:
https://doaj.org/article/9db092c8cdc34f92a0a8969eeb34ef38
Autor:
Annamari Ranki, Tapio Visakorpi, Pärt Peterson, Kalle Saksela, Jadwiga Roszkiewicz, Annemarie Poustka, Inge Krebs, Harri Sihto, Nina Nupponen, Hanna Nevala, Maria Pesonen, Vesna Blazevic, Ying Zhou, Soili Kytölä, Boguslaw Nedoszytko, Marketta Kähkönen, Sanna Syrjä, Ritva Karhu, Suvi Päivinen, Sonja Hahtola, Leena Karenko
Supplementary Figures S8 & S9 from Primary Cutaneous T-Cell Lymphomas Show a Deletion or Translocation Affecting NAV3, the Human UNC-53 Homologue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4183da8dd944d133f150a0dae1da04ab
https://doi.org/10.1158/0008-5472.22363527
https://doi.org/10.1158/0008-5472.22363527
Autor:
Annamari Ranki, Tapio Visakorpi, Pärt Peterson, Kalle Saksela, Jadwiga Roszkiewicz, Annemarie Poustka, Inge Krebs, Harri Sihto, Nina Nupponen, Hanna Nevala, Maria Pesonen, Vesna Blazevic, Ying Zhou, Soili Kytölä, Boguslaw Nedoszytko, Marketta Kähkönen, Sanna Syrjä, Ritva Karhu, Suvi Päivinen, Sonja Hahtola, Leena Karenko
Tables S2 & S3, Legends, and Supplementary Methods from Primary Cutaneous T-Cell Lymphomas Show a Deletion or Translocation Affecting NAV3, the Human UNC-53 Homologue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603e9d1aec376c61bc73a7eaa2eead97
https://doi.org/10.1158/0008-5472.22363524.v1
https://doi.org/10.1158/0008-5472.22363524.v1
Autor:
Annamari Ranki, Tapio Visakorpi, Pärt Peterson, Kalle Saksela, Jadwiga Roszkiewicz, Annemarie Poustka, Inge Krebs, Harri Sihto, Nina Nupponen, Hanna Nevala, Maria Pesonen, Vesna Blazevic, Ying Zhou, Soili Kytölä, Boguslaw Nedoszytko, Marketta Kähkönen, Sanna Syrjä, Ritva Karhu, Suvi Päivinen, Sonja Hahtola, Leena Karenko
Supplementary Figure S7 from Primary Cutaneous T-Cell Lymphomas Show a Deletion or Translocation Affecting NAV3, the Human UNC-53 Homologue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176d42a9ccec76984f2f113c1a9440ca
https://doi.org/10.1158/0008-5472.22363530.v1
https://doi.org/10.1158/0008-5472.22363530.v1