Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Kalitin, A. A."'
Publikováno v:
Research Results in Pharmacology 10(1): 1-6 (2024)
Introduction: Kappa-opioid receptor (KOR) signaling in the basolateral amygdala (BLA) underlies KOR agonist-induced aversion. In this study, we aimed to understand the individual and combined effects of KOR agonist U-50488 and p38 MAPK inhibitor SB20
Externí odkaz:
http://arxiv.org/abs/2402.05815
Publikováno v:
Фармация и фармакология (Пятигорск), Vol 11, Iss 5, Pp 432-442 (2024)
The study is focused to the investigation of a new kappa-opioid agonist RU-1205, which exhibits an analgesic effect without causing dysphoric or aversive actions. It is assumed that this effects may be due to its functional selectivity, or the presen
Externí odkaz:
https://doaj.org/article/d06f1fbe025a4b1aa1d03fdfb303f328
Publikováno v:
Research Results in Pharmacology, Vol 10, Iss 1, Pp 1-6 (2024)
Introduction: Kappa-opioid receptor (KOR) signaling in the basolateral amygdala (BLA) underlies KOR agonist-induced aversion. In this study, we aimed to understand the individual and combined effects of KOR agonist U-50488 and p38 MAPK inhibitor SB20
Externí odkaz:
https://doaj.org/article/90db203c0ad74a9595d5b309381a7552
Autor:
Glukhov, Ernest, Kalitin, Dmytro, Stepanenko, Darya, Zhu, Yimin, Nguyen, Thu, Jones, George, Patsahan, Taras, Simmerling, Carlos, Mitchell, Julie C., Vajda, Sandor, Dill, Ken A., Padhorny, Dzmitry, Kozakov, Dima
Publikováno v:
In Biophysical Journal 3 September 2024 123(17):2902-2909
Publikováno v:
Research Results in Pharmacology, Vol 9, Iss 4, Pp 21-29 (2023)
Introduction: Among the various receptor systems in the brain, the opioid receptors have been the subject of extensive research due to their integral role in pain modulation, reward processing, and emotional regulation. The kappa-opioid receptor (KOR
Externí odkaz:
https://doaj.org/article/c29d14f3fe5c4793ba02339d70e8e507
Autor:
Kalitin, Konstantin Y., Nevzorov, Alexey A., Babkov, Denis A., Spasov, Alexander A., Mukha, Olga Y.
Drug-target interaction (DTI) prediction has become a foundational task in drug repositioning, polypharmacology, drug discovery, as well as drug resistance and side-effect prediction. DTI identification using machine learning is gaining popularity in
Externí odkaz:
http://arxiv.org/abs/2009.12984
Akademický článek
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Publikováno v:
Фармация и фармакология (Пятигорск), Vol 11, Iss 1, Pp 4-18 (2023)
The development of new drugs to combat neuroinflammation is highly relevant as it opens up possibilities for the treatment of a wide range of diseases, including Alzheimer’s disease, Parkinson’s disease, epilepsy, schizophrenia, depression, and o
Externí odkaz:
https://doaj.org/article/b023f0e928034b23b79503d1648c74e3
Publikováno v:
Кубанский научный медицинский вестник, Vol 29, Iss 5, Pp 108-122 (2022)
Background. Schizophrenia is a socially signifi cant disease that takes a variety of forms. The form of the course determines prescribing antipsychotic drugs with a different range of clinical effects. The study of the pharmacological activity of neu
Externí odkaz:
https://doaj.org/article/900132e0c276436f9c93950ee2249d2d
Publikováno v:
Research Results in Pharmacology. 2023, Vol. 9 Issue 4, p21-29. 9p.