Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Kalishwaralal Kalimuthu"'
Autor:
Melinda Grace Rossan Mathews, Ravichandran Subramaniam, Saravanakumar Venkatachalam, Johnson Retnaraj Samuel Selvan Christyraj, Beryl Vedha Yesudhason, Kalishwaralal Kalimuthu, Manikandan Mohan, Jackson Durairaj Selvan Christyraj
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Fetal bovine serum (FBS) plays a pivotal role in animal cell culture. Due to ethical and scientific issues, searching for an alternative, comprising the three R’s (Refinement, Reduction and Replacement) gained global attention. In this con
Externí odkaz:
https://doaj.org/article/7bdd6ef24e0246f7aa3007440bff7300
Autor:
Chenicheri Kizhakkeveettil Keerthana, Tennyson Prakash Rayginia, Sadiq Chembothumparambil Shifana, Nikhil Ponnoor Anto, Kalishwaralal Kalimuthu, Noah Isakov, Ruby John Anto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Adenosine monophosphate-activated protein kinase (AMPK) is a key metabolic sensor that is pivotal for the maintenance of cellular energy homeostasis. AMPK contributes to diverse metabolic and physiological effects besides its fundamental role in gluc
Externí odkaz:
https://doaj.org/article/44429affa2ec4348b2695610f2def804
Autor:
Lekshmi R. Nath, Mundanattu Swetha, Vinod Vijayakurup, Arun Kumar Thangarasu, Nair Hariprasad Haritha, Anwar Shabna, Sreekumar U. Aiswarya, Tennyson P. Rayginia, C. K. Keerthana, Kalishwaralal Kalimuthu, Sankar Sundaram, Ravi Shankar Lankalapalli, Sreekumar Pillai, Rheal Towner, Noah Isakov, Ruby John Anto
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/1bfc53b0810545caae9783c41132c2c9
Autor:
Lekshmi R. Nath, Mundanattu Swetha, Vinod Vijayakurup, Arun Kumar Thangarasu, Nair Hariprasad Haritha, Anwar Shabna, Sreekumar U. Aiswarya, Tennyson P. Rayginia, C. K. Keerthana, Kalishwaralal Kalimuthu, Sankar Sundaram, Ravi Shankar Lankalapalli, Sreekumar Pillai, Rheal Towner, Noah Isakov, Ruby John Anto
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Our previous study has demonstrated that Uttroside B (Utt-B), a saponin isolated from the leaves of Solanum nigrum Linn induces apoptosis in hepatic cancer cells and exhibits a remarkable growth inhibition of Hepatocellular Carcinoma (HCC). Our innov
Externí odkaz:
https://doaj.org/article/27412c60fb1542d8b30f7778ed53e63b
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-7 (2019)
Abstract Extracellular vesicles (EVs) are membrane-bound phospholipid vesicles actively secreted by all cells. As they carry specific markers expressed by their parental cells, EVs are utilized to identify specific cells via liquid biopsy. To facilit
Externí odkaz:
https://doaj.org/article/3e6496c60b1047fcb9c77567ae3e19bf
Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma
Autor:
Mundanattu Swetha, Chenicheri K. Keerthana, Tennyson P. Rayginia, Lekshmi R. Nath, Nair Hariprasad Haritha, Anwar Shabna, Kalishwaralal Kalimuthu, Arun K. Thangarasu, Sreekumar U. Aiswarya, Somaraj Jannet, Sreekumar Pillai, Kuzhuvelil B. Harikumar, Sankar Sundaram, Nikhil Ponnoor Anto, Dee H. Wu, Ravi S. Lankalapalli, Rheal Towner, Noah Isakov, Sathyaseelan S. Deepa, Ruby John Anto
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 636 (2022)
We previously reported the remarkable potency of uttroside B (Utt-B), saponin-isolated and characterized in our lab from Solanum nigrum Linn, against HCC. Recently, the U.S. FDA approved Utt-B as an ‘orphan drug’ against HCC. The current study va
Externí odkaz:
https://doaj.org/article/b186c71c587e4df097a4a4b437a83fd0
Autor:
Kalishwaralal Kalimuthu, Bat-Chen Lubin, Andrii Bazylevich, Gary Gellerman, Ofer Shpilberg, Galia Luboshits, Michael A. Firer
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Peptide-drug-conjugates (PDCs) are being developed as an effective strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges to their successful application is the relatively low stability of
Externí odkaz:
https://doaj.org/article/769e9a94a2704d54834923808d687bc0
Autor:
Eom SooHyun, Youn Hyung-seop, Pandian SureshBabu, Sriram Muthuirulappan, Kalishwaralal Kalimuthu, BarathManiKanth Selvaraj, Gurunathan Sangiliyandi
Publikováno v:
Journal of Nanobiotechnology, Vol 8, Iss 1, p 16 (2010)
Abstract Background Oxidative stress is imperative for its morbidity towards diabetic complications, where abnormal metabolic milieu as a result of hyperglycemia, leads to the onset of several complications. A biological antioxidant capable of inhibi
Externí odkaz:
https://doaj.org/article/0332bf5a652c4a6996d103851e1112ed
Autor:
Park Jongsun, Eom Soo, Venkataraman Deepak, Kalishwaralal Kalimuthu, Sheikpranbabu Sardarpasha, Gurunathan Sangiliyandi
Publikováno v:
Journal of Nanobiotechnology, Vol 7, Iss 1, p 8 (2009)
Abstract The aim of this study is to determine the effects of silver nanoparticles (Ag-NP) on vascular endothelial growth factor (VEGF)-and interleukin-1 beta (IL-1β)-induced vascular permeability, and to detect the underlying signaling mechanisms i
Externí odkaz:
https://doaj.org/article/28a9f2f2968742d4a23a5b63fe681599
Autor:
Rathore, Anuranjan Singh, Gupta, Krishna Kant, Govindaraj, Senthil Kumar, Ajmani, Abhishek, Arivalagan, Jaison, Anto, Ruby John, Kalishwaralal, Kalimuthu, Chandran, Sam Aldrin
Publikováno v:
Journal of Biomolecular Structure & Dynamics; 2024, Vol. 42 Issue 19, p10439-10451, 13p