Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kalinga Pavan T. Silva"'
Autor:
Kalinga Pavan T. Silva, Anupama Khare
Publikováno v:
npj Antimicrobials and Resistance, Vol 2, Iss 1, Pp 1-10 (2024)
Abstract Apart from horizontal gene transfer and sequence-altering mutational events, antibiotic resistance can emerge due to the formation of tandem repeats of genomic regions. This phenomenon, also known as gene amplification, has been implicated i
Externí odkaz:
https://doaj.org/article/fe8c84412f1d407db6de8378e52523d9
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Antibiotics that have multiple cellular targets theoretically reduce the frequency of resistance evolution, but adaptive trajectories and resistance mechanisms against such antibiotics are understudied. Here we investigate these in methicill
Externí odkaz:
https://doaj.org/article/950b6bc9c2374e618df83bd5a10d9a1a
Autor:
Prithiviraj Chellamuthu, Kyle Naughton, Sahand Pirbadian, Kalinga Pavan T. Silva, Marko S. Chavez, Mohamed Y. El-Naggar, James Boedicker
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Bacteria naturally alter the redox state of many compounds and perform atom-by-atom nanomaterial synthesis to create many inorganic materials. Recent advancements in synthetic biology have spurred interest in using biological systems to manufacture n
Externí odkaz:
https://doaj.org/article/501a46a35dec461fb19fa41762608b88
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 6, p e1007166 (2019)
Signal crosstalk within biological communication networks is common, and such crosstalk can have unexpected consequences for decision making in heterogeneous communities of cells. Here we examined crosstalk within a bacterial community composed of fi
Externí odkaz:
https://doaj.org/article/0d995320eca241579b99e839842a0d25
The rise of antimicrobial resistance has motivated the development of antibiotics that have multiple cellular targets, to theoretically reduce the frequency of resistance evolution, but adaptive trajectories and genetic determinants of resistance aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45d94f54308eb792dcf718b0307daded
https://doi.org/10.1101/2022.11.30.518202
https://doi.org/10.1101/2022.11.30.518202
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 10, p e1005809 (2017)
In multispecies microbial communities, the exchange of signals such as acyl-homoserine lactones (AHL) enables communication within and between species of Gram-negative bacteria. This process, commonly known as quorum sensing, aids in the regulation o
Externí odkaz:
https://doaj.org/article/74f2b1c74ae4428dbe544e1436130062
Autor:
Mohamed Y. El-Naggar, Marko S. Chavez, Kalinga Pavan T. Silva, Frances Tran, James Q. Boedicker, Prithiviraj Chellamuthu
Publikováno v:
Microbial Biotechnology
Summary Microbes naturally build nanoscale structures, including structures assembled from inorganic materials. Here, we combine the natural capabilities of microbes with engineered genetic control circuits to demonstrate the ability to control biolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd0de6649831a59b4125cb54c78e4ab
https://doi.org/10.1111/1751-7915.13320
https://doi.org/10.1111/1751-7915.13320
Publikováno v:
Biophysical Journal. 112:1037-1044
Diverse microbial communities coordinate group behaviors through signal exchange, such as the exchange of acyl-homoserine lactones (AHLs) by Gram-negative bacteria. Cellular communication is prone to interference by neighboring microbes. One mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb205b0ff60ce969a616e64056bd3a67
https://doi.org/10.1016/j.bpj.2017.01.010
https://doi.org/10.1016/j.bpj.2017.01.010
Publikováno v:
Physical Review E. 99
Bacteria communicate with each other to coordinate macroscale behaviors including pathogenesis, biofilm formation, and antibiotic production. Empirical evidence suggests that bacteria are capable of communicating at length scales far exceeding the si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cba871a005c7533af3035782a8f587b
https://doi.org/10.1103/physreve.99.042409
https://doi.org/10.1103/physreve.99.042409
Publikováno v:
Physical biology. 16(3)
Cell-cell interaction networks have been examined in many high diversity microbial communities using macroscale approaches. Microscale studies of multispecies communities are lacking and it remains unclear how macroscale trends scale down to small gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9db49744ce97347b7096ef53307c60
https://pubmed.ncbi.nlm.nih.gov/30665208
https://pubmed.ncbi.nlm.nih.gov/30665208