Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kalina Timcheva"'
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102528- (2023)
Summary: Here, we present a detailed protocol to study the role of a human nuclear m6A RNA reader, YTHDC1, on chromatin-associated RNA targets. We describe steps for RNA extraction coupled to subnuclear fractionation to identify and study RNA-based r
Externí odkaz:
https://doaj.org/article/c358a0253d974a3a954b25066e49339a
Autor:
Elien Heylen, Paulien Verstraete, Linde Van Aerschot, Shauni L. Geeraerts, Tom Venken, Kalina Timcheva, David Nittner, Jelle Verbeeck, Jonathan Royaert, Marion Gijbels, Anne Uyttebroeck, Heidi Segers, Diether Lambrechts, Jan Cools, Kim De Keersmaecker, Kim R. Kampen
Publikováno v:
British Journal of Cancer, 128, 1862-1878. Nature Publishing Group
Background One-third of cancers activate endogenous synthesis of serine/glycine, and can become addicted to this pathway to sustain proliferation and survival. Mechanisms driving this metabolic rewiring remain largely unknown. Methods NKX2–1 overex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b561d055b5ae618b1b53b77cf1c7c9
https://cris.maastrichtuniversity.nl/en/publications/e59dc2d5-6ba2-43f7-aff4-42706658a52b
https://cris.maastrichtuniversity.nl/en/publications/e59dc2d5-6ba2-43f7-aff4-42706658a52b
Publikováno v:
Genes
Genes, 2022, 13 (4), pp.597. ⟨10.3390/genes13040597⟩
Genes, 2022, 13 (4), pp.597. ⟨10.3390/genes13040597⟩
In eukaryotes, the heat shock response is orchestrated by a transcription factor named Heat Shock Factor 1 (HSF1). HSF1 is mostly characterized for its role in activating the expression of a repertoire of protein-coding genes, including the heat shoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2733c74bef3324e9dab5695f96e456b9
https://hal.science/hal-03755523/document
https://hal.science/hal-03755523/document
Autor:
Kalina Timcheva, Solenne Dufour, Leila Touat-Todeschini, Callum Burnard, Marie-Christine Carpentier, Florent Chuffart, Rémy Merret, Marion Helsmoortel, Sabrina Ferré, Aude Grézy, Yohann Couté, Sophie Rousseaux, Saadi Khochbin, Claire Vourc’h, Cécile Bousquet-Antonelli, Rosemary Kiernan, Daphné Seigneurin-Berny, André Verdel
Publikováno v:
Cell Reports
Cell Reports, 2022, 41 (11), pp.111784. ⟨10.1016/j.celrep.2022.111784⟩
Cell Reports, 2022, 41 (11), pp.111784. ⟨10.1016/j.celrep.2022.111784⟩
Heat stress (HS) induces a cellular response leading to profound changes in gene expression. Here, we show that human YTHDC1, a reader of N