Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kalidip Choudhury"'
Autor:
Aaron B. Kantor, Sebastian J. Osterfeld, Shan X. Wang, Heng Yu, Danfeng Yao, Toshiro Saito, M. Luis Carbonell, Kalidip Choudhury
The ability to characterize the binding kinetics of drug-target interactions in a biologically relevant matrix, such as serum or plasma, remains a fundamental challenge in drug discovery. We apply a novel label-based giant magnetoresistance (GMR) bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59cdbff0e8be5968d5ba222b7712b06e
https://doi.org/10.1101/2021.08.29.458058
https://doi.org/10.1101/2021.08.29.458058
Autor:
Kalidip Choudhury, Fabio Cominelli, Sushma Shivaswamy, Paola Menghini, Alexander Rodriguez-Palacios, Charles A. Dinarello, Natalia Aladyshkina, Daniele Corridoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f06ab0a7edb97c261b60a753a558e2
https://doi.org/10.1016/s0016-5085(17)30648-0
https://doi.org/10.1016/s0016-5085(17)30648-0
Autor:
Heng Yu, Kalidip Choudhury, Sebastian J. Osterfeld, Takashi Nakasawa, Chihiro Manri, Masayoshi Momiyama, Toshiro Saito
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 198:114015
We demonstrated that effects of serum matrix on molecular interactions between drugs and target proteins can be investigated in real time using magnetic bio-sensing techniques. A giant magneto-resistive (GMR) sensor was used on which target proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61007b66ec682f18f6ae6ad1bf566675
https://doi.org/10.1016/j.jpba.2021.114015
https://doi.org/10.1016/j.jpba.2021.114015
Publikováno v:
Immunology Today. 20:161-165
Human diseases frequently occur in discrete, genetically susceptible groups rather than being distributed randomly in the population. As discussed at a recent symposium**The symposium ‘MHC-based Therapeutics in Immunological Disorders' was part of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c89e3c719a03d3c1b1c4f36cbc30b7b9
https://doi.org/10.1016/s0167-5699(98)01390-5
https://doi.org/10.1016/s0167-5699(98)01390-5
Autor:
A. Hickman, M. F. Dunn, Munirathiram Sundaramoorthy, E. Woehl, Thomas L. Poulos, Kalidip Choudhury, T. Yonetani
Publikováno v:
Journal of Biological Chemistry. 269:20239-20249
The role of the proximal histidine ligand in peroxidase function was studied by replacing the His side chain in cytochrome c peroxidase with Gln, Glu, or Cys. In addition, a double mutant was prepared where His-175 is converted to Gln and the site of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a639f410e0105041196ad2fe51a5ff04
https://doi.org/10.1016/s0021-9258(17)31982-8
https://doi.org/10.1016/s0021-9258(17)31982-8
Publikováno v:
Journal of Biological Chemistry. 267:25656-25659
Using site-directed mutagenesis, a double mutant in yeast cytochrome c peroxidase (CCP) has been constructed where the proximal ligand, His175, has been converted to glutamine and the neighboring Trp191 has been converted to phenylalanine. The refine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f933a7a4a57951fef90154ea122bda55
https://doi.org/10.1016/s0021-9258(18)35655-2
https://doi.org/10.1016/s0021-9258(18)35655-2
Publikováno v:
Journal of the American Chemical Society. 113:7755-7757
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f56dbd4c3bf50d3038177051f21b93a6
https://doi.org/10.1021/ja00020a044
https://doi.org/10.1021/ja00020a044
Autor:
Oscar Willemsen, Mario P. Marzocchi, Thomas L. Poulos, Kalidip Choudhury, Francesca Neri, Giulietta Smulevich
Publikováno v:
Spectroscopy of Biological Molecules ISBN: 9789401041669
Peroxidases are heme containing enzymes which catalyze the reduction of hydrogen peroxide by different substrates. Peroxidases are characterized by the presence of a polar proximal hydrogen-bond between the Nδ atom of the His fifth ligand and the O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::984a1c6a53d2a44f279a7f2cd6ff2be1
https://doi.org/10.1007/978-94-011-0371-8_57
https://doi.org/10.1007/978-94-011-0371-8_57